Uvavanyo lweAldolase

Umxholo

• Yintoni ialdolase?
• Kutheni le nto uvavanyo lwe-aldolase luyalelwe?
• Ulawulwa njani uvavanyo lwealdolase?
• Buphi ubungozi bovavanyo lwe-aldolase?
• Ulungiselela njani uvavanyo lwe-aldolase?
• Zithetha ntoni iziphumo zovavanyo?
• Amanqanaba aphezulu okanye angaqhelekanga e-aldolase
• Amanqanaba e-aldolase asezantsi

Yintoni ialdolase?

Umzimba wakho uguqula uhlobo lweswekile ekuthiwa yiglucose ibe ngamandla. Le nkqubo ifuna amanyathelo aliqela ahlukeneyo. Elinye icandelo elibalulekileyo kwinkqubo y-enzyme eyaziwa ngokuba yi-aldolase.

I-Aldolase inokufumaneka kuwo wonke umzimba, kodwa ukugxila kuphezulu kwimisipha yesibindi kunye nesibindi.

Nangona kungekho kulungelelaniswa ngokuthe ngqo, amanqanaba aphezulu e-aldolase egazini angenzeka ukuba kukho umonakalo kwimisipha yakho okanye kwisibindi.

Kutheni le nto uvavanyo lwe-aldolase luyalelwe?

Uvavanyo lwe-aldolase lulinganisa inani le-aldolase egazini lakho. Ukunyuka kwamanqanaba ale enzyme kunokubonisa ingxaki enkulu yezempilo.

I-aldolase ephakanyisiweyo ihlala iluphawu lokonakala kwemisipha okanye kwesibindi. Umzekelo, ukonakala kwezihlunu kwintliziyo kukhupha i-aldolase ngobuninzi. Umonakalo wesibindi, njenge-hepatitis okanye i-cirrhosis, nayo inyusa amanqanaba e-aldolase.

Kwixesha elidlulileyo, uvavanyo lwe-aldolase lwalusetyenziselwa ukujonga ukonakala kwesibindi okanye kwemisipha. Namhlanje, oogqirha basebenzisa iimvavanyo ezithile zegazi, kubandakanya:

• creatine kinase (CK)
• i-alanine aminotransferase (ALT)
• i-aspartate aminotransferase (AST)

Uvavanyo lwe-aldolase alusasetyenziswa rhoqo. Nangona kunjalo, inoku-odolwa ukuba une-muscular dystrophy.

Ingasetyenziselwa ukuvavanya ukuphazamiseka kwemfuza okunqabileyo kwezihlunu zamathambo, ezinje nge-dermatomyositis kunye ne-polymyositis (PM).

Ulawulwa njani uvavanyo lwealdolase?

Uvavanyo lwe-aldolase luvavanyo lwegazi, ke kuya kufuneka unike isampulu yegazi. Isampulu ihlala ithathwa ligcisa.

Ukuthatha le sampulu, bafaka inaliti kumthambo wengalo okanye yesandla sakho baqokelele igazi elikwityhubhu. Isampulu ke ithunyelwa kwilebhu yohlalutyo kunye neziphumo ezichazwe kugqirha wakho, oya kuthi aziphonononge kunye nawe.

Buphi ubungozi bovavanyo lwe-aldolase?

Unokufumana ukungonwabi okuthile, njengentlungu kwindawo yovavanyo, xa kuthathwa isampulu yegazi. Kunokubakho nentlungu emfutshane okanye ebuhlungu kwisiza emva kovavanyo.

Ngokubanzi, umngcipheko wovavanyo lwegazi awuncinci. Iingozi ezinokubakho zibandakanya:

• ubunzima bokufumana isampulu, okukhokelela kwiinti ezininzi zeenaliti
• ukopha kakhulu kwindawo yenaliti
• ukuwa isiqaqa ngenxa yokulahleka kwegazi
• Ukuqokelelwa kwegazi phantsi kolusu, okwaziwa njengehematoma
• usulelo apho ulusu lwaphuke ngenaliti

Ulungiselela njani uvavanyo lwe-aldolase?

Ugqirha wakho uza kukuxelela indlela yokulungiselela uvavanyo. Ngokwesiqhelo, ngekhe utye okanye usele nantoni na kwiiyure ezi-6 ukuya kwezi-12 phambi kovavanyo. Fumana iingcebiso ezingakumbi ngokuzila ukutya ngaphambi kovavanyo lwegazi.

Kubalulekile ukuba uqaphele ukuba umthambo unokuchaphazela iziphumo zovavanyo lwe-aldolase. Yazisa ugqirha wakho malunga nenkqubo yakho yesiqhelo yokuzilolonga. Unokuxelelwa ukuba unciphise umthambo kangangeentsuku ezininzi phambi kovavanyo, njengoko umthambo unokubangela ukuba ube neziphumo eziphezulu zexeshana ze-aldolase.

Ugqirha wakho unokucela ukuba uyeke ukuthatha amayeza anokutshintsha iziphumo zovavanyo. Qiniseka ukuba uxelela ugqirha wakho ngawo onke amayeza owathathayo. Oku kubandakanya zombini amayeza amayeza kunye ne-over-the-counter (OTC).

Zithetha ntoni iziphumo zovavanyo?

Uluhlu oluthile lovavanyo olungaqhelekanga lungahluka kancinci kwilabhoratri, kwaye kukho umahluko omncinci phakathi kwamanqanaba aqhelekileyo kumadoda nabasetyhini.

Ngokubanzi, iziphumo eziqhelekileyo zinokuvela kwiiyunithi ze-1.0 ukuya kwi-7.5 ilitha nganye (U / L) yabantu abaneminyaka eli-17 ubudala nangaphezulu. Iziphumo eziqhelekileyo zabantu ukuya kuthi ga kwi-16 iminyaka ubudala zinokufikelela kwi-14.5 U / L.

Amanqanaba aphezulu okanye angaqhelekanga e-aldolase

Amanqanaba aphezulu okanye angaqhelekanga anokubangelwa yimeko yezempilo, kubandakanya:

• ukonakala kwezihlunu
• dermatomyositis
• hepatitis wentsholongwane
• Umhlaza wesibindi, ipancreas, okanye iprostate
• Izihlunu zemisipha
• ukuhlaselwa yintliziyo
• polymyositis
• Ileukemia
• ukutyumka

Ukuvavanywa kwe-Aldolase yeemeko ezibangela amanqanaba aphezulu e-aldolase (hyperaldolasemia) ayithethi ngqo. Iimeko okanye izifo ezibangela ukunciphisa izihlunu kunokubangela i-hyperaldolasemia. Ekuqaleni, ukutshatyalaliswa kwemisipha kubangela amanqanaba aphezulu e-aldolase. Nangona kunjalo, amanqanaba e-aldolase eneneni ayancipha njengoko isixa semisipha emzimbeni sincipha.

Yazisa ugqirha wakho ukuba ngaba usandula ukubandakanyeka kwimisebenzi enzima, enokubangela ukuba ube neziphumo eziphezulu okwexeshana okanye ezilahlekisayo.

Amanqanaba e-aldolase asezantsi

Ngaphantsi kwe-2.0 ukuya kwi-3.0 U / L ithathwa njengenqanaba eliphantsi le-aldolase. Amanqanaba asezantsi e-aldolase anokubonwa kubantu abane:

• ukunganyamezelani kwe-fructose
• isifo sokumosha izihlunu
• Ukuhamba kade kwemisipha