Uvavanyo lwe-T3

I-Triiodothyronine (T3) yidlala lengqula. Idlala indima ebalulekileyo kulawulo lomzimba lwe-metabolism (iinkqubo ezininzi ezilawula inqanaba lomsebenzi kwiiseli nakwizicubu).

Uvavanyo olwenziwa elebhu lunokwenziwa ukulinganisa isixa se-T3 egazini lakho.

Isampulu yegazi iyafuneka.

Umboneleli wakho wokhathalelo lwempilo uya kukuxelela ukuba ngaba ufuna ukuyeka ukuthatha nawaphi na amayeza phambi kovavanyo olunokuchaphazela iziphumo zakho zovavanyo. SUKUYEKE ukuthatha nawaphi na amayeza ngaphandle kokuqala uthethe nomboneleli wakho.

Iziyobisi ezinokunyusa imilinganiselo ye-T3 zibandakanya:

• Iipilisi zokulawula inzala
• Clofibrate
• Estrogens
• Imethadone
• Amayeza athile e-herbal

Iziyobisi ezinokunciphisa imilinganiselo ye-T3 zibandakanya:

• Amiodarone
• I-Anabolic steroids
• Androgens
• Iziyobisi Antithyroid (umzekelo, propylthiouracil kunye methimazole)
• ILithium
• IPhenytoin
• Ipropranolol

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Olu vavanyo lwenziwa ukujonga umsebenzi we-thyroid. Umsebenzi we-thyroid uxhomekeke kwisenzo se-T3 kunye namanye amahomoni, kubandakanya i-hormone evuselela i-thyroid (TSH) kunye ne-T4.

Ngamanye amaxesha kunokuba luncedo ukulinganisa zombini i-T3 kunye ne-T4 xa kuvavanywa ukusebenza kwe-thyroid.

Uvavanyo olupheleleyo lwe-T3 lulinganisa i-T3 encanyathiselwe kwiiproteni kunye nokudada simahla egazini.

Uvavanyo lwe-T3 yasimahla lilinganisa i-T3 edadayo simahla egazini. Uvavanyo lwe-T3 yasimahla aluchanekanga kwaphela kunolo lwe-T3 iyonke.

Umboneleli wakho unokulucebisa olu vavanyo ukuba uneempawu zesifo se-thyroid, kubandakanya:

• I-pituitary gland ayivelisi ixabiso eliqhelekileyo lezinye okanye zonke i-hormone (hypopituitarism)
• Ukugqithisa kwe-thyroid gland (hyperthyroidism)
• Ukungasebenzi kwe-thyroid gland (hypothyroidism)
• Ukuthatha amayeza e-hypothyroidism

Uluhlu lwamaxabiso aqhelekileyo zezi:

• Iyonke i-T3-60 ukuya kwi-180 yee-nanograms ngedesilitha nganye (ng / dL), okanye i-0.9 ukuya kwi-2.8 i-nanomoles ilitha nganye (nmol / L)
• Iifoto zasimahla eziyi-T3 - 130 ukuya kuma-450 ngedesilitha nganye (ipg / dL), okanye i-2.0 ukuya kwi-7.0 yeepikomo ngeyure nganye (pmol / L)

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho malunga nentsingiselo yeziphumo zakho zovavanyo.

Amaxabiso esiqhelo aqwalaselwe ubudala kubantu abangaphantsi kweminyaka engama-20. Jonga kumboneleli wakho malunga neziphumo zakho ezithile.

Inqanaba eliphezulu kuneliqhelekileyo le-T3 inokuba luphawu loku:

• I-thyroid gland engaphezulu (umzekelo, isifo se-Graves)
• I-T3 thyrotoxicosis (inqabile)
• Ityhefu
• Ukuthatha amayeza e-thyroid okanye izongezo ezithile (eziqhelekileyo)
• Isifo sesibindi

Inqanaba eliphezulu le-T3 linokwenzeka ekukhulelweni (ngakumbi ukugula kwasekuseni ekupheleni kwekota yokuqala) okanye ngokusetyenziswa kweepilisi zolawulo lokuzalwa okanye i-estrogen.

Inqanaba elisezantsi kuneliqhelekileyo linokubangelwa:

• Ixesha elinzima elifutshane okanye ezinye izifo zexesha elide
• I-Thyroiditis (ukudumba okanye ukudumba kwe-thyroid gland - isifo sikaHashimoto lolona hlobo luqhelekileyo)
• Indlala
• Ukungasebenzi kwe-thyroid gland

Ukusilela kweSelenium kubangela ukwehla kokuguqulwa kwe-T4 ukuya kwi-T3, kodwa akucaci ukuba oku kukhokelela kumanqanaba asezantsi e-T3 ebantwini.

Kukho umngcipheko omncinci ochaphazelekayo ekuthatheni igazi lakho: imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye kwaye ukusuka kwelinye icala lomzimba ukuya kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Triiodothyronine; T3 radioimmunoassay; Ityhefu goiter enobuhlungu - T3; Idlala lengqula - T3; Thyrotoxicosis - T3; Isifo samangcwaba - T3

• Uvavanyo lwegazi

UGuber HA, uFarag AF. Uvavanyo lomsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 24.

UKim G, uNandi-Munshi D, uDiblasi CC. Ukuphazamiseka kwedlala lengqula. Ku: Gleason CA, Juul SE, ii-eds. Izifo zika-Avery Zomntwana osandul 'ukuzalwa. Ngomhla we-10. IPhiladelphia, PA: Elsevier; Ngo-2018: isahluko 98.

USalvatore D, uCohen R, uKopp PA, uLarsen PR. I-thyroid pathophysiology kunye novavanyo lokuqonda isifo. Ku: UMelmed S, uAuchus RJ, uGoldfine AB, uKoenig RJ, uRosen CJ, ii-eds. Incwadi ebhaliweyo kaWilliam ye-Endocrinology. Umhla we-14. IPhiladelphia, PA: Elsevier; 2020: isahl 11.

I-Weiss RE, Refetoff S. Umsebenzi wovavanyo lwe-thyroid. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 78.