Umbhali: Marcus Baldwin
Umhla Wokudalwa: 16 Isilimela 2021
Hlaziya Umhla: 16 Eyenkanga 2024
Anonim
Subcutaneous delivery of sumatriptan in the treatment of migraine - Video abstract: 19171
Ividiyo: Subcutaneous delivery of sumatriptan in the treatment of migraine - Video abstract: 19171

Umxholo

I-Sumatriptan isetyenziselwa ukunyanga iimpawu zentloko ye-migraine (ebukhali, ebuhlungu yintloko ngamanye amaxesha ehamba nesicaphucaphu okanye ubuntununtunu kwisandi nokukhanya). ISumatriptan ikudidi lwamayeza abizwa ngokuba yi-serotonin receptor agonists. Isebenza ngokunciphisa imithambo yegazi entloko, imise imiqondiso yeentlungu ekubeni ithunyelwe kwingqondo, kwaye kuthintele ukukhutshwa kwezinto ezithile zendalo ezibangela iintlungu, isicaphucaphu, kunye nezinye iimpawu ze-migraine. I-Sumatriptan ayikuthinteli ukuhlaselwa kwe-migraine okanye ukunciphisa inani leentloko onazo.

Sumatriptan uza elucwecweni ukuthatha ngomlomo. Ngokuqhelekileyo ithathwa kwisibonakaliso sokuqala se-migraine intloko.Ukuba iimpawu zakho ziphucula emva kokuba uthathe i-sumatriptan kodwa ubuye emva kweeyure ezingama-2 okanye ngaphezulu, ungathatha ithebhulethi yesibini. Nangona kunjalo, ukuba iimpawu zakho aziphuculanga emva kokuba uthathe i-sumitriptan, sukuthatha ithebhulethi yesibini ungakhange ubize ugqirha wakho. Ugqirha wakho uya kukuxelela elona nani liphezulu leetafile onokuthi uzithathe kwisithuba seeyure ezingama-24. Landela umkhombandlela kwileyibhile yakho kagqirha, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze naliphi na icandelo ongaliqondi. Thatha i-sumatriptan ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.


Ungathabatha idosi yakho yokuqala yesumatriptan kwiofisi kagqirha okanye kwelinye iziko lonyango apho unokujongwa khona xa usabela kakubi.

Fowunela ugqirha wakho ukuba iintloko zakho azibangcono okanye zenzeke rhoqo emva kokuthatha i-sumatriptan.

Ukuba uthatha i-sumatriptan rhoqo okanye ixesha elide kunexesha elicetyiswayo, iintloko zakho zinokuba mandundu okanye zinokwenzeka rhoqo. Akufanele uthathe i-sumatriptan okanye nayiphi na iyeza lonyango lwentloko ngaphezulu kweentsuku ezili-10 ngenyanga. Biza ugqirha wakho ukuba ufuna ukuthatha i-sumatriptan ukunyanga ngaphezulu kweentloko ezine kwinyanga e-1.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

La mayeza ngamanye amaxesha amiselweyo kwezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-sumatriptan,

  • xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-sumatriptan, nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze sumatriptan. Buza usokhemesti wakho uluhlu lwezithako.
  • ungathathi i-sumatriptan ukuba uthathe amayeza alandelayo kwiiyure ezingama-24 ezidlulileyo: ezinye i-serotonin receptor agonists ezinje nge-almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt) , okanye zolmitriptan (Zomig); okanye amayeza ohlobo lwe-ergot anje nge-bromocriptine (Parlodel), cabergoline, dihydroergotamine (DHE 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Cafergot, Ergomar, Wigraine), methylergonovine (Methergine) ), nangegolide (iPermax).
  • musa ukuthatha i-sumatriptan ukuba uthatha i-monoamine oxidase A (MAO-A) inhibitor enjenge-isocarboxazid (Marplan), phenelzine (Nardil), okanye tranylcypromine (Parnate) okanye ukuba uthathe elinye lala mayeza kwezi veki zimbini zidlulileyo.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: acetaminophen (Tylenol); i-antidepressants efana ne-amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), kunye nepritriprine Utywala); i-aspirin kunye nezinye iyeza ezichasayo (i-NSAIDs) ezinje nge-ibuprofen (Advil, Motrin) kunye ne-naproxen (Aleve, Naprosyn); i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo njenge-citalopram (i-Celexa), i-escitalopram (i-Lexapro), i-fluoxetine (i-Prozac, i-Sarafem, kwi-Symbyax), i-fluvoxamine, i-paroxetine (i-Paxil), kunye ne-sertraline (i-Zoloft); kunye nokukhetha i-serotonin / norepinephrine reuptake inhibitors (SNRIs) enje nge-desvenlafaxine (Pristiq), duloxetine (Cymbalta), sibutramine (Meridia), kunye ne-venlafaxine (Effexor). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akujonge ngononophelo kwiziphumo ebezingalindelekanga.
  • uxelele ugqirha wakho ukuba une okanye isifo sentliziyo wakha; isifo sentliziyo; i-angina (iintlungu zesifuba); ukubetha kwentliziyo okungaqhelekanga; ukubetha okanye 'ukubetha okuncinci'; okanye iingxaki zokuhamba ezifana nemithambo yevaricose, amahlwili egazi emilenzeni, isifo sikaRaynaud (iingxaki zokuhamba kwegazi ukuya eminweni, iinzwane, iindlebe, kunye nempumlo), okanye isifo sesisu (isifo segazi kunye nentlungu esiswini ebangelwa kukuhla kwegazi kuye amathumbu). Ugqirha wakho unokukuxelela ukuba ungathathi i-sumatriptan.
  • xelela ugqirha wakho ukuba uyatshaya okanye utyebile; ukuba ukhe wakha waba noxinzelelo oluphezulu lwegazi, icholesterol ephezulu, isifo seswekile, ukuxhuzula, okanye isibindi okanye isifo sezintso; ukuba baye batyhubela exesheni (utshintsho lobomi); okanye ukuba kukho naliphi na ilungu losapho elinaso okanye esakha sanesifo sentliziyo okanye ukubetha.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ucwangcisa ukuba neentlobano zesini ngelixa usebenzisa la mayeza, thetha nogqirha wakho malunga neendlela ezisebenzayo zolawulo lokuzalwa. Ukuba ukhulelwa ngelixa uthatha i-sumatriptan, biza ugqirha wakho.
  • kufuneka wazi ukuba lo iyeza ukuze ube yokozela okanye Uyagula. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


ISumatriptan inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • ukugungxula
  • imvakalelo yokuncwina
  • ukuziva ushushu okanye uyabanda
  • ukozela
  • ukudinwa
  • ubuthathaka
  • isiyezi
  • isisu esimoshakele
  • urhudo
  • isicaphucaphu
  • izihlunu zemithambo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

  • intlungu, ukuqina, uxinzelelo, okanye ubunzima esifubeni, emqaleni, entanyeni, kunye / okanye emhlathini
  • intetho ecothayo okanye enzima
  • ukudinwa
  • Ukuqhekeka ngumbilo obandayo
  • ukuqhawukelwa ngumphefumlo
  • ubuthathaka okanye ukuba ndindisholo kwengalo okanye umlenze
  • ngesiquphe okanye ngokuqaqanjelwa sisisu
  • ngokukhawuleza, ukubetha, okanye ukubetha kwentliziyo okungaqhelekanga
  • Urhudo olunegazi
  • ukugabha
  • ngesiquphe okanye ngokuqaqanjelwa sisisu
  • ukunciphisa umzimba ngesiquphe
  • isiyezi okanye umbala oluhlaza neminwe neenzwane
  • ubunzima bokuphefumla okanye ukugwinya
  • ububomvu, ukudumba, okanye ukurhawuzelela kwamehlo, kobuso, kwemilebe okanye komqala
  • irhashalala
  • urhwebo
  • utshintsho kumbono
  • ukuxhuzula

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).


Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Beka it bushushu, kude ubushushu obugqithisileyo kunye ukufuma (hayi kwindlu yangasese).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help.Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho. Uxinzelelo lwegazi kufuneka luhlolwe rhoqo.

Kuya kufuneka ugcine idayari yentloko ngokubhala phantsi xa unentloko kwaye xa uthatha i-sumatriptan.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • Imitrex® Amacwecwe
  • Treximet® (Iqulethe iNaproxen, iSumatriptan)
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