Zonisamide

Umxholo

• Ngaphambi kokuba uthathe i-zonisamide,
• I-Zonisamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, tsalela ugqirha ngokukhawuleza:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Zonisamide isetyenziselwa ukudibanisa namanye amayeza ukunyanga iintlobo ezithile zokubanjwa. UZonisamide ukwiklasi yamayeza abizwa ngokuba zii-anticonvulsants. Isebenza ngokunciphisa izinto ezingaqhelekanga zombane kwingqondo.

UZonisamide uza njengephilisi emayithathwe ngomlomo. Ihlala ithathwa kanye okanye kabini ngemini kunye okanye ngaphandle kokutya. Ukukunceda ukhumbule ukuthatha i-zonisamide, yithathe malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-zonisamide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya zonke iifomsile; ungahluleli, ungahlaleli, okanye uzityumze.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-zonisamide kwaye ngokuthe ngcembe andise idosi yakho, hayi rhoqo rhoqo kube kanye kwiiveki ezi-2.

I-Zonisamide inokunceda ukulawula imeko yakho kodwa ayizukuyinyanga. Ingathatha iiveki ezi-2 okanye ngaphezulu ngaphambi kokuba uve isibonelelo se-zonisamide. Qhubeka nokuthatha i-zonisamide nokuba uziva uphilile. Sukuyeka ukuthatha i-zonisamide ngaphandle kokuthetha nogqirha wakho, nokuba ngaba uneziphumo ebezingalindelekanga ezinje ngotshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwimood. Ukuba ngequbuliso uyeka ukuthatha i-zonisamide, ukubanjwa kwakho kunokuba mandundu. Ugqirha wakho uya kunciphisa umthamo wakho ngokuthe ngcembe.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango kunye ne-zonisamide kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-zonisamide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-zonisamide, i-diuretics ('iipilisi zamanzi'), amayeza omlomo weswekile, iziyobisi zesulfa, okanye nawaphi na amanye amayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: amiodarone (Cordarone, Pacerone); ii-antifungals ezinje nge-itraconazole (Sporanox) kunye ne ketoconazole (Nizoral); iicarbonic anhydrase inhibitors ezinje ngeacetazolamide (Diamox) kunye ne methazolamide; i-clarithromycin (i-Biaxin, kwi-Prevpac); I-diltiazem (iCardizem, iDilacor, iTiazac); i-erythromycin (i-EES, i-E-Mycin, i-Erythrocin); i-fluvoxamine (iLuvox); I-HIV protease inhibitors efana ne-indinavir (Crixivan), nelfinavir (Viracept), kunye ne-ritonavir (Norvir, eKaletra); amayeza okuba nesifo sesisu, isifo sokuhamba, isifo sikaParkinson, izilonda, okanye iingxaki zomchamo; amanye amayeza okubanjwa kubandakanya i-carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin, Phenytek), kunye ne-valproic acid (Depakene, Depakote); nefazodone (Serzone); izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iipatches, iiringi kunye nenaliti); ipioglitazone (Actos, eActoplus, kwiDuactact); irifabutin (Mycobutin); irifampin (Rifadin, Rimactane); i-troleandomycin (TAO) (ayifumaneki e-US); Kunye neverapamil (Calan, Covera, Isoptin, Verelan). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba ulandela ukutya kwe-ketogenic (ukutya okunamafutha aphezulu, ukutya okuneecarbohydrate ezisetyenziselwa ukulawula ukuxhuzula) okanye ukuba uneengxaki zokuphefumla, isibindi sezintso, okanye isifo semiphunga. Xelela ugqirha wakho ukuba urhudo ngoku, okanye ukuba uvela urhudo nanini na ngexesha lonyango lwakho.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Kuya kufuneka usebenzise ulawulo lokuzalwa ukukhusela ukukhulelwa ngexesha lonyango lwakho. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngelixa uthatha i-zonisamide, tsalela ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa. Ukuba uncancisa ngexesha lonyango lwakho, umntwana wakho unokufumana i-zonisamide kubisi lwebele. Jonga umntwana wakho ngokusondeleyo ukulala okungaqhelekanga okanye ukufumana ubunzima obuthathaka.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-zonisamide.
• Kuya kufuneka uyazi ukuba i-zonisamide inokukwenza wozele. Sukuqhuba imoto, sebenzisa oomatshini, okanye wenze imisebenzi eyingozi de ube uyazi indlela elikuchaphazela ngayo eli yeza.
• Kuya kufuneka uyazi ukuba i-zonisamide inokunciphisa ukubila komzimba kwaye yenze kube nzima ukuba umzimba wakho uphole xa kushushu kakhulu. Oku kwenzeka rhoqo kwimozulu efudumeleyo nakubantwana abathatha i-zonisamide. (Abantwana akufuneki bathathe i-zonisamide, kodwa kwezinye iimeko, inokumiselwa ngugqirha.) Kuya kufuneka uphephe ukubonakaliswa bubushushu kwaye ubize ugqirha ngoko nangoko ukuba unefiva kunye / okanye awubilo njengesiqhelo.
• Kuya kufuneka uyazi ukuba impilo yakho yengqondo inokutshintsha ngeendlela ezingalindelekanga kwaye ungazibulala (ucinga ngokuzenzakalisa okanye ukuzibulala okanye ukucwangcisa okanye ukuzama ukwenza njalo) ngelixa uthatha i-zonisamide kunyango lwesifo sokuwa, ukugula ngengqondo, okanye ezinye iimeko. Inani elincinci labantu abadala kunye nabantwana abaneminyaka emi-5 ubudala nangaphezulu (malunga ne-1 kubantu abangama-500) abathathe ii-anticonvulsants ezifana ne-zonisamide ukunyanga iimeko ezahlukeneyo ngexesha lezifundo zeklinikhi bazibulala ngexesha lonyango lwabo. Abanye baba bantu bakhulise iingcinga zokuzibulala kunye nokuziphatha kwiveki e-1 emva kokuba beqalisile ukuthatha amayeza. Kukho umngcipheko wokuba unokufumana utshintsho kwimpilo yakho yengqondo ukuba uthatha amayeza e-anticonvulsants anje nge-zonisamide, kodwa kusenokubakho umngcipheko wokuba uya kufumana utshintsho kwimpilo yakho yengqondo ukuba imeko yakho ayinyangwa. Wena kunye nogqirha wakho niya kuthatha isigqibo sokuba ngaba ingozi yokuthatha iyeza le-anticonvulsant inkulu kuneengozi zokungawasebenzisi amayeza. Wena, usapho lwakho, okanye umntu omkhathalelayo kufuneka ubize ugqirha wakho ngoko nangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: uloyiko; ukuphazamiseka okanye ukungazinzi; okutsha okanye ukuhla kokucaphuka, uxinzelelo, okanye uxinzelelo; ukwenza izinto eziyingozi; ubunzima bokuwa okanye ukulala; ndlongondlongo, umsindo okanye ubundlobongela; i-mania (i-frenzied, i-mood engaqhelekanga) ukuthetha okanye ukucinga ngokufuna ukuzenzakalisa okanye ukuzibulala; Ukurhoxa kubahlobo nakusapho; ukuxakeka kukufa nokufa; ukuphisa ngezinto ezixabisekileyo; okanye naluphi na olunye utshintsho olungaqhelekanga kwindlela oziphethe ngayo okanye kwimood. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyazi ukuba zeziphi iimpawu ezinokuba nobuzaza ukuze babize ugqirha ukuba awukwazi ukuzifunela unyango ngokwakho.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yegrapefruit ngelixa uthatha eli yeza.

Sela iiglasi ze-6-8 zamanzi yonke imihla ngexesha lonyango lwakho ne-zonisamide.

Thetha nogqirha wakho malunga nokuba wenzeni ukuba uphoswa yidosi ye-zonisamide. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Zonisamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• ukuhla ukusinda
• utshintsho kwincasa
• urhudo
• ukuqhina
• isilungulela
• umlomo owomileyo
• intloko ebuhlungu
• isiyezi
• ukudideka
• ukucaphuka
• ubunzima bokulala okanye ukulala
• ubunzima ngememori
• iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha ezandleni okanye ezinyaweni
• iintshukumo zamehlo ezingalawulekiyo
• umbono kabini

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga, kodwa ukuba ufumana enye yazo, tsalela ugqirha ngokukhawuleza:

• irhashalala
• ukudumba okanye ukuxobuka kolusu
• ukwanda okanye ukubanjwa okuhlala ixesha elide
• iintlungu zomqolo ngesiquphe
• isisu esibuhlungu
• intlungu xa uchama
• umchamo wegazi okanye omnyama
• umkhuhlane, umqala obuhlungu, Ukugodola, ukukhohlela, kunye neminye imiqondiso yosulelo
• izilonda emlonyeni
• ukutyunyuzwa ngokulula
• ubunzima bokucinga ngamagama okanye ingxaki yokuthetha
• ubunzima bokucinga okanye ukugxila
• ukunqongophala kolungelelwaniso
• ubunzima bokuhamba
• ubuthathaka obukhulu
• iintlungu ezinzima zemisipha
• ukudinwa kakhulu
• Ukuphelelwa ngumdla wokutya
• ngokukhawuleza, ukuphefumla okungaphantsi
• ukubetha kwentliziyo ngokungaqhelekanga
• ukulahleka kwengqondo

I-Zonisamide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

I-Zonisamide inokubangela i-metabolic acidosis (amanqanaba asezantsi ngendlela engaqhelekanga kwinto ethile yendalo egazini). I-metabolic acidosis esele inganyangwa ixesha elide inokunyusa umngcipheko wokuba ezinye iingxaki zonyango, kubandakanya amatye ezintso kunye neengxaki zamathambo ezinokukhokelela ekuqhekekeni, ziya kukhula. Ukunganyangwa kwe-metabolic acidosis kunokubangela ukukhula okucothayo kunye nokwehla kobude bokugqibela ebantwaneni. Thetha nogqirha wakho malunga neengozi zokuthatha i-zonisamide.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni.Yigcine kubushushu begumbi kwaye kude nokukhanya, ubushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukubetha kwentliziyo kancinci
• ukuphefumla okucothayo
• isiyezi
• isiqaqa
• isiqaqa (ukulahleka kwengqondo ixesha elithile)

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho unokuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-zonisamide.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Indawo yaseZangran^®