Izibonelelo ezi-7 zezeMpilo zeServeratrol Supplements

Umxholo

• Yintoni iResveratrol?
• 1. Izincedisi zeResveratrol zisenokukunceda ukunciphisa uxinzelelo lwegazi
• 2. Inefuthe elifanelekileyo kwiiFatasi zamafutha
• 3. Yolula ubude bexesha lokuphila kwezinye izilwanyana
• 4. Ikhusela uBongo
• 5. Inokuthi yonyuse u-Insulin Sensitivity
• 6. Isenokuthomalalisa iintlungu ezihlangeneyo
• 7. I-Resveratrol Ngamana inganqanda iiseli zomhlaza
• Iingozi kunye neenkxalabo malunga neResveratrol Supplements
• Umgca osezantsi

Ukuba uvile ukuba iwayini ebomvu inokunceda ukunciphisa i-cholesterol, kunokwenzeka ukuba uvile nge-resveratrol - isityalo esineziqhamo ezininzi ezifumaneka kwiwayini ebomvu.

Kodwa ngaphaya kokuba yinxalenye esempilweni yewayini ebomvu kunye nokunye ukutya, i-resveratrol inamandla okuphucula impilo ngokwayo.

Ngapha koko, ii-resveratrol supplements ziye zadityaniswa kwizibonelelo ezininzi zempilo ezinomdla, kubandakanya ukukhusela ukusebenza kwengqondo kunye nokunciphisa uxinzelelo lwegazi (,,,).

Eli nqaku licacisa into ekufuneka uyazi malunga ne-resveratrol, kubandakanya ezisixhenxe zezibonelelo zayo eziphambili ezinokubakho kwezempilo.

Yintoni iResveratrol?

I-Resveratrol sisityalo esisebenza njenge-antioxidant. Iindawo zokutya eziphezulu zibandakanya iwayini ebomvu, iidiliya, amanye amajikijolo kunye namandongomane (,).

Eli khompawundi lihlala ligxile ikakhulu kulusu kunye nembewu yeediliya kunye namajikijolo. La malungu omdiliya afakiwe ekubilisweni kwewayini ebomvu, yiyo loo nto uxinzelelo oluphezulu lwe-resveratrol (,).

Nangona kunjalo, uninzi lophando kwi-resveratrol lwenziwe kwizilwanyana kunye neetyhubhu zokuvavanya kusetyenziswa izixa eziphezulu zekhompawundi (,).

Kuphando olunqongopheleyo ebantwini, uninzi lujolise kwiifom ezongezelelekileyo zekhompawundi, koxinzelelo oluphezulu kunolo unokufumana ngokutya ().

I-Resveratrol yinkomfa efana ne-antioxidant efumaneka kwiwayini ebomvu, amajikijolo kunye namandongomane. Uninzi lophando lomntu lusebenzise izongezo ezinamanqanaba aphezulu e-resveratrol.

1. Izincedisi zeResveratrol zisenokukunceda ukunciphisa uxinzelelo lwegazi

Ngenxa yeempawu zayo zokulwa ne-antioxidant, i-resveratrol inokuba sisongezo esithembisayo sokunciphisa uxinzelelo lwegazi ().

Uphengululo luka-2015 luphelile ukuba iidosi eziphezulu zinokunceda ukunciphisa uxinzelelo olwenziwe kwiindonga zomthambo xa intliziyo ibetha ().

Olu hlobo loxinzelelo lubizwa ngokuba yi-systolic uxinzelelo lwegazi, kwaye lubonakala njengenani eliphezulu kufundo lwexinzelelo lwegazi.

Uxinzelelo lwegazi lweSystolic luhamba lunyuka kunye nobudala, njengoko imithambo iyaqina. Xa iphakamileyo, yinto enobungozi kwisifo senhliziyo.

I-Resveratrol inokulifeza eli gazi-ukwehlisa isiphumo ngokunceda ukuvelisa ngaphezulu i-nitric oxide, ebangela ukuba imithambo yegazi iphumle (,).

Nangona kunjalo, ababhali beso sifundo bathi uphando oluthe kratya luyafuneka ngaphambi kokuba kwenziwe iingcebiso ezithile malunga nelona dosi ilungileyo ye-resveratrol yokwandisa uxinzelelo lwegazi.

I-Resveratrol supplements inokunceda ukunciphisa uxinzelelo lwegazi ngokunyusa imveliso ye-nitric oxide.

2. Inefuthe elifanelekileyo kwiiFatasi zamafutha

Izifundo ezininzi kwizilwanyana ziphakamise ukuba i-resveratrol supplements inokutshintsha amafutha egazi ngendlela esempilweni (,).

Uphononongo luka-2016 londla iigundane ezineprotein ephezulu, ukutya okunamafutha aphezulu kunye nokubanika izongezo ze-resveratrol.

Abaphandi bafumene i-avareji yamanqanaba e-cholesterol kunye nobunzima bomzimba weempuku ezinciphileyo, kwaye amanqanaba abo "alungileyo" e-HDL cholesterol enyukile ().

I-Resveratrol ibonakala ichaphazela amanqanaba e-cholesterol ngokunciphisa ifuthe le-enzyme elawula ukuveliswa kwe-cholesterol ().

Njenge-antioxidant, inokunciphisa i-oxidation ye-cholesterol "embi" yeLDL. I-LDL oxidation inegalelo kulwakhiwo lweplaki kwiindonga zomthambo (,).

Kwisifundo esinye, abathathi-nxaxheba banikwa isicatshulwa somdiliya esomelezwe nge-resveratrol eyongezelelweyo.

Emva kweenyanga ezintandathu zonyango, i-LDL yabo yehle nge-4.5% kwaye i-LDL yabo ene-oxidized yehle nge-20% xa kuthelekiswa nabathathi-nxaxheba abathathe isicatshulwa somdiliya esingafakwanga okanye i-placebo ().

I-Resveratrol supplements inokunceda amafutha egazi kwizilwanyana. Njenge-antioxidant, banokunciphisa i-LDL ye-cholesterol odixation.

3. Yolula ubude bexesha lokuphila kwezinye izilwanyana

Amandla ekhompawundi okwandisa ixesha lokuphila kwizinto ezahlukeneyo eziphilayo iyeyona ndawo iphambili kuphando ().

Kukho ubungqina bokuba i-resveratrol isebenze iijethi ezithile ezithintela izifo zokuguga ().

Kuyasebenza ukufezekisa oku ngendlela efanayo nesithintelo sekhalori, ebonakalise isithembiso ekwandiseni ixesha lokuphila ngokutshintsha indlela ohlobo olubonisa ngayo (,).

Nangona kunjalo, akucaci ukuba le khompawundi inokuba nefuthe elifanayo ebantwini.

Uphengululo lwezifundo eziphonononge olu nxibelelwano lufumanise ukuba i-resveratrol inyuse ixesha lokuphila kwi-60% yezinto eziphilayo ezifundwayo, kodwa isiphumo sasinamandla kwizinto eziphilayo ezazingahambelani kangako nabantu, ezinje ngeentshulube kunye nentlanzi ().

Izongezo zeResveratrol zandisile ixesha lokuphila kwizifundo zezilwanyana. Nangona kunjalo, akucaci ukuba baya kuba nefuthe elifanayo kubantu.

4. Ikhusela uBongo

Izifundo ezininzi zicebise ukuba ukusela iwayini ebomvu kunokunceda ukucothisa ukwehla kwengqondo okunxulumene nobudala (,,,).

Oku kunokuba ngenxa ye-antioxidant kunye ne-anti-inflammatory function ye-resveratrol.

Kubonakala ngathi kuphazamisa iziqwengana zeprotein ezibizwa ngokuba yi-beta-amyloids, ezibalulekileyo ekuyileni iipleyiti eziyimbalasane yesifo se-Alzheimer's (,).

Ukongeza, ikhompawundi inokucwangcisa uchungechunge lweziganeko ezikhusela iiseli zengqondo kumonakalo ().

Ngelixa olu phando lunomdla, izazinzulu zisenemibuzo malunga nokuba umzimba womntu uyakwazi njani ukusebenzisa i-resveratrol eyongezelelweyo, ethintela ukusetyenziswa kwayo kwangoko njengesongezelelo ukukhusela ingqondo (,).

I-antioxidant kunye ne-anti-inflammatory compound, i-resveratrol ibonisa isithembiso ekukhuseleni iiseli zengqondo kumonakalo.

5. Inokuthi yonyuse u-Insulin Sensitivity

I-Resveratrol ibonakalisiwe inezibonelelo ezininzi zeswekile, ubuncinci kwizifundo zezilwanyana.

Ezi zibonelelo zibandakanya ukwanda kweemvakalelo ze-insulin kunye nokukhusela iingxaki kwisifo seswekile (,,,).

Enye inkcazo malunga nendlela i-resveratrol isebenza ngayo kukuba inokumisa i-enzyme ethile ekuguquleni i-glucose ibe yi-sorbitol, ishukela yotywala.

Xa i-sorbitol eninzi isakha kubantu abanesifo seswekile, inokwenza iselfowuni eyonakalisayo yoxinzelelo lwe-oxidative (, 31).

Nazi ezinye izibonelelo ezimbalwa i-resveratrol enokuba nazo kubantu abanesifo seswekile ():

• Ngamana unokukhusela kuxinzelelo lwe-oxidative: Isenzo sayo se-antioxidant sinokunceda ekukhuseleni uxinzelelo lwe-oxidative, olwenza ezinye zeengxaki zesifo seswekile.
• Inceda ukunciphisa ukudumba: I-Resveratrol icingelwa ukunciphisa ukudumba, igalelo eliphambili kwizifo ezingapheliyo, kubandakanya neswekile.
• Sebenzisa i-AMPK: Le yiprotein enceda umzimba ukuba uchithe iswekile. Ukusebenza kwe-AMPK kunceda ukugcina amanqanaba eswekile esezantsi esezantsi.

I-Resveratrol inokubonelela ngakumbi ngezibonelelo kubantu abanesifo seswekile kunabo bangenayo. Kwisifundo esinye sezilwanyana, iwayini ebomvu kunye ne-resveratrol yayizezona zisebenza ngokuchanekileyo kwi-antioxidants kwiigundane ezinesifo seswekile kuneempuku ezazingenayo ().

Abaphandi bathi le khompawundi inokusetyenziselwa ukunyanga isifo seswekile kunye neengxaki zayo kwixa elizayo, kodwa kufuneka uphando olungaphezulu.

I-Resveratrol incede iimpuku zikhulise ubuntununtunu obungcono be-insulin kunye nokulwa iingxaki zesifo seswekile. Kwixesha elizayo, abantu abanesifo seswekile banokuzuza kunyango lwe-resveratrol.

6. Isenokuthomalalisa iintlungu ezihlangeneyo

Isifo samathambo sisifo esixhaphakileyo esikhokelela kwintlungu yokudibana kunye nokuphulukana nokuhamba ().

Izongezo ezisekwe kwizityalo zifundwa njengendlela yokunyanga nokukhusela iintlungu ezidibeneyo. Xa kuthathwa njengesongezelelo, i-resveratrol inokunceda ukukhusela i-cartilage ekuwohlokeni (,).

Ukuqhekeka kweCartilage kunokubangela iintlungu ezidibeneyo kwaye yenye yeempawu eziphambili zesifo samathambo ().

Olunye uphononongo lufake i-resveratrol kumadolo emivundla ene-arthritis kwaye yafumanisa ukuba le mivundla ifumene umonakalo omncinci kwi-cartilage yabo ().

Olunye uphando kwiityhubhu zovavanyo nakwizilwanyana lucebisile ukuba ikhompawundi inokubanakho ukunciphisa ukudumba nokukhusela ukonakala kwamalungu (,,,).

I-Resveratrol inokunceda ekunciphiseni iintlungu ngokudibeneyo ngokuthintela intlala ekuqhekekeni.

7. I-Resveratrol Ngamana inganqanda iiseli zomhlaza

I-Resveratrol ifundwe, ngakumbi kwiityhubhu zovavanyo, ngokukwazi kwayo ukuthintela nokunyanga umhlaza. Nangona kunjalo, iziphumo zixutywe (,,).

Kwizifundo zesilwanyana kunye neetyhubhu zovavanyo, kubonisiwe ukuba kuliwa iintlobo ezahlukeneyo zeseli zomhlaza, kubandakanya isisu, ikholoni, ulusu, ibele kunye neprostate (,,,,).

Nantsi indlela i-resveratrol enokulwa ngayo neeseli zomhlaza:

• Inokuthintela ukukhula komhlaza weseli: Inokuthintela iiseli zomhlaza ekuziphindaphindeni nasekusasazeni ().
• I-Resveratrol inokutshintsha ukutshintsha kwemfuza: Inokutshintsha ukubonakaliswa kofuzo kwiiseli zomhlaza ukuthintela ukukhula kwazo ().
• Inokuba neziphumo zehomoni: I-Resveratrol inokuphazamisa indlela echazwa ngayo iihomoni ezithile, ezinokuthi zigcine ii-cancer ezixhomekeke kwihomoni zisasazeke ().

Nangona kunjalo, okoko izifundo ukuza kuthi ga ngoku zenziwe kwiityhubhu zovavanyo kunye nasezilwanyaneni, uphando oluninzi luyafuneka ukubona ukuba ingaba esi sixhobo sinokusetyenziselwa njani unyango lomhlaza womntu.

I-Resveratrol ibonise umdla womsebenzi wokuthintela umhlaza kwiityhubhu zokuvavanya nakwizifundo zezilwanyana.

Iingozi kunye neenkxalabo malunga neResveratrol Supplements

Akukho bungozi bukhulu buveziweyo kwizifundo ezisebenzise i-resveratrol supplements. Abantu abaphilileyo babonakala bebanyamezela kakuhle ().

Nangona kunjalo, kufanele kuqatshelwe ukuba azikho ngokwaneleyo iingcebiso eziqinisekileyo malunga nokuba kufuneka umntu athathe i-resveratrol engakanani ukuze afumane izibonelelo zempilo.

Kwaye kukho izilumkiso, ngakumbi ngokubhekisele kwindlela i-resveratrol enokusebenzisana ngayo namanye amayeza.

Ukusukela ukuba iidosi eziphezulu ziye zaboniswa ukuba ziyeke igazi ekunqandeni kwiityhubhu zovavanyo, kunokwenzeka ukuba inyuse ukopha okanye ukugruzuka xa kuthathwa iziyobisi ezichasayo, ezinje ngeparpar okanye warfarin, okanye iintlungu ezithomalalisayo (,).

I-Resveratrol ikwathintela ezinye ii-enzymes ezikunceda ukucacisa izinto ezithile emzimbeni. Oko kuthetha ukuba amanye amayeza anokwakha ukuya kumanqanaba angakhuselekanga. Oku kubandakanya amayeza athile oxinzelelo lwegazi, iindlela zokuxhalaba kunye ne-immunosuppressants ().

Ukuba ngoku usebenzisa amayeza, unokufuna ukukhangela ugqirha ngaphambi kokuzama i-resveratrol.

Okokugqibela, kuxoxwa ngokubanzi ukuba ingakanani i-resveratrol umzimba ongayisebenzisa ngokwenyani kwizongezo nakweminye imithombo ().

Nangona kunjalo, abaphandi bafunda iindlela zokwenza ukuba i-resveratrol ibe lula emzimbeni ukuba uyisebenzise (,).

Ngelixa izongezo ze-resveratrol zinokuba zikhuselekile kubantu abaninzi, banokusebenzisana namayeza athile kwaye okwangoku akukabikho sikhokelo sicacileyo sendlela yokuwasebenzisa ngokufanelekileyo.

Umgca osezantsi

I-Resveratrol yi-antioxidant enamandla enamandla amakhulu.

Kuboniswa isithembiso ngokubhekisele kwiimeko ezahlukeneyo zempilo, kubandakanya isifo sentliziyo kunye nesifo samathambo. Nangona kunjalo, isikhokelo esicacileyo sedosi sisasilela.