Fasciitis Eosinophilic

I-Eosinophilic fasciitis (EF) sisifo apho izicwili ziphantsi kolusu nangaphezulu kwesihlunu, esibizwa ngokuba yi-fascia, esidumbayo, esidumbileyo nesityebileyo. Ulusu oluseengalweni, emilenzeni, entanyeni, esiswini okanye ezinyaweni lunokudumba ngokukhawuleza. Imeko inqabile kakhulu.

I-EF inokubonakala ifana ne-scleroderma, kodwa ayihambelani. Ngokungafaniyo ne-scleroderma, kwi-EF, iminwe ayibandakanyekanga.

Isizathu se-EF asaziwa. Iimeko ezinqabileyo zenzekile emva kokuthatha izongezo ze-L-tryptophan. Kubantu abanale meko, iiseli ezimhlophe zegazi, ezibizwa ngokuba zii-eosinophil, zakha kwiimisipha kunye nezicubu. I-Eosinophils inxulunyaniswa negalelo lakho. I-syndrome ixhaphake kakhulu kubantu abaneminyaka engama-30 ukuya kuma-60.

Iimpawu zingabandakanya:

• Ukuthantamisa kunye nokudumba kolusu ezingalweni, emilenzeni, okanye ngamanye amaxesha kumalungu (ubukhulu becala kumacala omabini omzimba)
• Isifo samathambo
• Isifo seCarpal tunnel
• Intlungu yezihlunu
• Ulusu olujiyileyo olukhangeleka ngathi lucekethekile

Uvavanyo olunokwenziwa lunokubandakanya:

• I-CBC ngokwahluka
• I-Gamma globulins (uhlobo lweprotein yamajoni omzimba)
• Izinga le-sedimentation ye-Erythrocyte (ESR)
• IMRI
• Imisipha biopsy
• I-biopsy yesikhumba (i-biopsy kufuneka ibandakanye izicubu ezinzulu ze-fascia)

ICorticosteroids kunye namanye amayeza acinezela ukuzikhusela komzimba asetyenziselwa ukunciphisa iimpawu. La mayeza asebenza ngakumbi xa eqala kwangoko kwesi sifo. Izidakamizwa ezichasayo ezichasayo (i-NSAIDs) zinokukunceda ukunciphisa iimpawu.

Kwiimeko ezininzi, imeko iyahamba kwisithuba seminyaka emi-1 ukuya kwemi-3. Nangona kunjalo, iimpawu zihlala ixesha elide okanye zibuye.

IArthritis yingxaki enqabileyo ye-EF. Abanye abantu banokuba neengxaki ezinzulu zegazi okanye i-cancer ehlobene negazi, njenge-aplastic anemia okanye i-leukemia. Imbonakalo iba mandundu ngakumbi ukuba kwenzeka izifo zegazi.

Fowunela umboneleli wakho wezempilo ukuba uneempawu zesi sifo.

Akukho sithintelo saziwayo.

Isifo sikaShulman

• Imisipha yangaphandle yangaphandle

UAronons JK. Zama. Ku: Aronson JK, ed. Iziphumo ebezingalindelekanga zikaMeyler zeziyobisi. Ngomhla we-16. I-Waltham, MA: Elsevier BV ;; Ngo-2016: 220-221.

UJames WD, u-Elston DM, nyanga i-JR, i-Rosenbach MA, i-IM ye-Neuhaus. Izifo ezinxulumene nezihlunu. Ku: James WD, Elston DM, Phatha uJR, Rosenbach MA, Neuhaus IM, ii-eds. Izifo zikaAndrews zolusu: Unyango lweKlinikhi. Umhla we-13. IPhiladelphia, PA: Elsevier; 2020: isahl 8.

U-Lee LA, Werth VP. Ulusu kunye nezifo zamathambo. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, ii-eds. Incwadi kaKelley kunye neFirestein yeRheumatology. Ngomhla we-10. IPhiladelphia, PA: Elsevier; Ngo-2017: isahluko 43.

UPinal-Fernandez I, uSelva-O ’uCallaghan A, uGrau JM. Ukuchonga kunye nokuhlelwa kwe-eosinophilic fasciitis. Ukuzikhusela ngokuzenzekelayo Rev. Ngo-2014; 13 (4-5): 379-382. IINKCUKACHA: 24424187 www.ncbi.nlm.nih.gov/pubmed/24424187.

Umbutho weSizwe weengxaki ezinqabileyo. Fasciitis Eosinophilic. rarediseases.org/rare-diseases/eosinophilic-fasciitis/. Ukuhlaziywa ngo-2016. Kufumaneka ngo-Matshi 6, 2017.