I-Angioedema

I-Angioedema kukudumba okufana nemingxuma, kodwa ukudumba kuphantsi kwesikhumba endaweni yomphezulu.

Imihlathi ihlala ibizwa ngokuba yiwelts. Kukudumba komphezulu. Kuyenzeka ukuba ube ne-angioedema ngaphandle kwemingxunya.

I-Angioedema inokubangelwa kukungabikho komzimba. Ngexesha lokuphendula, i-histamine kunye nezinye iikhemikhali zikhutshwa kwigazi. Umzimba ukhupha i-histamine xa amajoni omzimba efumanisa into yangaphandle ebizwa ngokuba yi-allergen.

Kwiimeko ezininzi, unobangela we-angioedema akafumaneki.

Oku kulandelayo kunokubangela i-angioedema:

• I-dander yezilwanyana (izikali zesikhumba esichiziweyo)
• Ukubonakaliswa emanzini, ukukhanya kwelanga, ukubanda okanye ubushushu
• Ukutya (njengamajikijolo, i-shellfish, intlanzi, amantongomane, amaqanda kunye nobisi)
• Ukulunywa zizinambuzane
• Amayeza (iziyobisi)
• Umungu

I-Hives kunye ne-angioedema nayo inokwenzeka emva kosulelo okanye ezinye izifo (kubandakanya ukuphazamiseka okuzenzekelayo njenge-lupus, kunye neleukemia kunye ne-lymphoma).

Ifom ye-angioedema isebenza kwiintsapho kwaye inezinto ezahlukeneyo ezibangela, iingxaki kunye nonyango. Oku kubizwa ngokuba li-angioedema yelifa.

Uphawu oluphambili kukudumba ngesiquphe ngaphantsi komphezulu wolusu. Iwelts okanye ukudumba kumphezulu wolusu nako kunokukhula.

Ukudumba kuhlala kwenzeka emehlweni nasemilebeni. Inokufumaneka nakwizandla, iinyawo, nasemqaleni. Ukudumba kunokwenza umgca okanye kunwenwe ngakumbi.

Iwelts zibuhlungu kwaye zinokurhawuzelela. Oku kwaziwa njengeenyosi (urticaria). Zijika zijike zidumbe ukuba ziyacaphuka. Ukudumba okunzulu kwe-angioedema kunokuba buhlungu.

Ezinye iimpawu zingabandakanya:

• Ukuxinana esiswini
• Ukuphefumla ubunzima
• Amehlo adumbileyo nomlomo
• Ukugquma kwamehlo (chemosis)

Umboneleli wezempilo uya kujonga kulusu lwakho kwaye abuze ukuba ukhe wafunyanwa kuyo nayiphi na into ekucaphukisayo. Ukuba umqala wakho uchaphazelekile, uvavanyo lomzimba lunokubonisa izandi ezingaqhelekanga (i-stridor) xa uphefumla.

Uvavanyo lwegazi okanye uvavanyo lokungabikho komzimba lunoku-odolwa.

Iimpawu ezinobumnene azinakufuna unyango. Ukumodareyitha ukuya kwiimpawu ezinzima kunokufuna ukunyangwa. Ukuphefumla ubunzima yimeko engxamisekileyo.

Abantu abane-angioedema kufuneka:

• Gwema nayiphi na i-allergen eyaziwayo okanye i-trigger ebangela iimpawu zabo.
• Gwema nawaphi na amayeza, amayeza, okanye izongezo ezingamiselwanga ngumboneleli.

Ukucofa okupholileyo okanye ukufunxa kunokuthomalalisa iintlungu.

Amayeza asetyenziselwa ukunyanga i-angioedema abandakanya:

• AmaNtsholongwane
• Amayeza alwa nokudumba (iicorticosteroids)
• I-Epinephrine shots (abantu abanembali yeempawu ezinzima banokuzithwala nazo)
• Amayeza e-inhaler anceda ukuvula i-airways

Ukuba umntu unengxaki yokuphefumla, funa uncedo lwezonyango kwangoko. Uxinzelelo olunzima nolusongela ubomi luza kwenzeka ukuba umqala udumbile.

I-Angioedema engachaphazeli ukuphefumla isenokungonwabi. Ihlala ingenabungozi kwaye ihamba ngeentsuku ezimbalwa.

Fowunela umnikezeli wakho ukuba:

• I-Angioedema ayiphenduli kunyango
• Inzima
• Awuzange ube ne-angioedema ngaphambili

Yiya kwigumbi likaxakeka okanye fowunela inombolo yongxamiseko yendawo (enje nge-911) ukuba zikhona ezi mpawu zilandelayo:

• Izandi zokuphefumla ngokungaqhelekanga
• Kunzima ukuphefumla okanye ukuvutha
• Ukufa isiqaqa

Edema Angioneurotic; Welts; Uguquko - angioedema; Imihlathi - i-angioedema

IBarkdale AN, uMuelleman RL. Allergy, hypersensitivity, kunye ne-anaphylaxis. Ku: Iindonga RM, iHockberger RS, iGausche-Hill M, ii-eds. Unyango lukaRosen oluNgxamisekileyo: iikhonsepthi kunye nokuziqhelanisa neklinikhi. Umhla we-9. IPhiladelphia, PA: Elsevier; 2018: isahluko 109.

IDinulos JGH. Urticaria, angioedema, kunye nepruritus. Ku: I-Dinulos JGH, ed.Ugqirha wezonyango waseHabif. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2021: isahluko 6.

IDreskin SC. Urticaria kunye angioedema. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahl 237.