Ukuveliswa ngaphezulu kwe-ovari ye-androgens

Ukuveliswa ngaphezulu kwe-ovarian ye-androgens yimeko apho ii-ovari zenza i-testosterone eninzi kakhulu. Oku kukhokelela kuphuhliso lweempawu zobudoda kumfazi. IiAndrogens ezivela kwamanye amalungu omzimba zinokubangela ukuba iimpawu zamadoda ziphuculwe kwabasetyhini.

Kwabasetyhini abasempilweni, ii-ovari kunye ne-adrenal gland zivelisa malunga ne-40% ukuya kwi-50% ye-testosterone yomzimba. Izidumbu zama-ovari kunye ne-polycystic ovary syndrome (i-PCOS) inokubangela imveliso ye-androgen eninzi kakhulu.

Isifo se-Cushing yingxaki ye-pituitary gland ekhokelela kwi-corticosteroids engaphezulu. ICorticosteroids ibangela utshintsho kumzimba wobudoda kubafazi. Izidumba kwincindi yeadrenal zinokubangela ukuveliswa kakhulu kwe-androgens kwaye kunokukhokelela kwiimpawu zomzimba wamadoda kubafazi.

Amanqanaba aphezulu e-androgens kumfazi anokubangela:

• Amabala
• Utshintsho kubume bomzimba wabasetyhini
• Nciphisa ubungakanani besifuba
• Ukwanda kweenwele zomzimba kwipateni eyindoda, njengasebusweni, esilevini nakwisisu
• Ukungabikho kwexesha lokuya esikhathini (amenorrhea)
• Ulusu olunamafutha

Olu tshintsho lunokwenzeka:

• Yandisa kubungakanani be-clitoris
• Ukujula kwelizwi
• Ukwandisa ubunzima bemisipha
• Ukucoca iinwele kunye nokulahleka kweenwele ngaphambili kwentloko entloko kumacala omabini entloko

Umboneleli wakho wezempilo uya kwenza uvavanyo lomzimba. Naliphi na uvavanyo lwegazi kunye nokucinga okuyalelweyo kuya kuxhomekeka kwiimpawu zakho, kodwa kunokubandakanya:

• Uvavanyo lwe-17-hydroxyprogesterone
• Uvavanyo lwe-ACTH (engaqhelekanga)
• Uvavanyo lwecholesterol
• Ukuskena i-CT
• Uvavanyo lwegazi lwe-DHEA
• Uvavanyo lweglucose
• Uvavanyo lwe-insulin
• Iipelvic ultrasound
• Uvavanyo lweprolactin (ukuba amaxesha afika ngokufuthi okanye hayi kwaphela)
• Uvavanyo lweTesttosterone (yasimahla kunye ne testosterone iphela)
• Uvavanyo lwe-TSH (ukuba kukho ukulahleka kweenwele)

Unyango luxhomekeke kwingxaki ebangela ukwanda kwemveliso ye-androgen. Amayeza anokunikwa ukunciphisa ukuveliswa kweenwele kubafazi abaneenwele zomzimba ezigqithileyo, okanye ukulawula imijikelo yokuya exesheni. Ngamanye amaxesha, kunokufuneka kwenziwe utyando ukususa i-ovarian okanye i-adrenal tumor.

Impumelelo yonyango ixhomekeke kwisizathu semveliso engaphezulu kwe-androgen. Ukuba imeko ibangelwa yi-ovarian tumor, utyando lokususa ithumba inokulungisa ingxaki. Uninzi lwamathumba e-ovari alunomhlaza (benign) kwaye awuyi kubuya emva kokuba esusiwe.

Kwi-polycystic ovary syndrome, la manyathelo alandelayo anokunciphisa iimpawu ezibangelwa ngamanqanaba aphezulu e-androgen:

• Ukubeka iliso ngenyameko
• Ukuhla ukusinda
• Utshintsho kwizidlo
• Amayeza
• Ukuzilolonga rhoqo

Ukungachumi kunye neengxaki ngexesha lokukhulelwa zinokwenzeka.

Abasetyhini abane-polycystic ovary syndrome banokuba semngciphekweni omkhulu woku:

• Seswekile
• Igazi elonyukayo
• Cholesterol ephezulu
• Ukutyeba kakhulu
• Umhlaza wesibeleko

Abasetyhini abane-polycystic ovary syndrome banokunciphisa utshintsho lwabo lweengxaki zexesha elide ngokugcina ubunzima obuqhelekileyo ngokutya okusempilweni kunye nokuzilolonga rhoqo.

• Ukuvelisa amaqanda ngaphezulu
• Uphuhliso lweefollicle

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