Iplasma amino acid

Iplasma amino acid luvavanyo lokuhlola olwenziwa kwiintsana ezijonga izixa zeamino acid egazini. Ii-amino acids zizitena zokwakha iiproteni emzimbeni.

Uninzi lwexesha, igazi litsalwa kumthambo ngaphakathi kwengqiniba okanye ngasemva kwesandla.

Kwiintsana okanye abantwana abancinci, isixhobo esibukhali esibizwa ngokuba yi-lancet sinokusetyenziselwa ukugqobhoza ulusu.

• Igazi liqokelela kwityhubhu yeglasi encinci ebizwa ngokuba yipipette, okanye kwisilayidi okanye kumtya wovavanyo.
• Ibhandeji ibekwa phezu kwendawo ukunqanda ukopha.

Isampulu yegazi ithunyelwa elebhu. Kukho iintlobo ezininzi zeendlela ezisetyenziselwa ukumisela amanqanaba eamino acid egazini.

Umntu owenza uvavanyo akufuneki atye iiyure ezi-4 phambi kovavanyo.

Kunokubakho iintlungu ezimbalwa okanye ulwamvila xa kufakwa inaliti. Unokuziva ubethwa sisiza emva kokuba kuthathwe igazi. Intonga yenaliti iya kubangela ukuba usana okanye umntwana akhale.

Olu vavanyo lwenziwa ukulinganisa inqanaba leeamino acid egazini.

Inqanaba elonyukayo le-amino acid luphawu olomeleleyo. Oku kubonisa ukuba kukho ingxaki ekukwazini komzimba ukuphula (i-metabolism) i-amino acid.

Uvavanyo lusenokusetyenziselwa ukukhangela ukuhla kwamanqanaba ee-amino acid egazini.

Ukunyuka okanye ukwehla kwamanqanaba ee-amino acid egazini kunokwenzeka ngeemfiva, ukungondleki ngokwaneleyo, kunye neemeko ezithile zonyango.

Yonke imilinganiselo ikwii-micromoles kwilitha nganye (µmol / L). Amaxabiso aqhelekileyo anokwahluka phakathi kweelebhu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga neziphumo zakho ezithile zovavanyo.

UAlanine:

• Abantwana: 200 ukuya ku-450
• Abantu abadala: 230-510

IAlpha-aminoadipic acid:

• Bantwana: ayifumaneki
• Abantu abadala: akafumaneki

I-alpha-amino-N-butyric acid:

• Abantwana: 8 ukuya ku-37
• Abantu abadala: 15 ukuya ku-41

Arginine:

• Abantwana: 44 ukuya kwi-120
• Abantu abadala: 13-64

I-Asparagine:

• Abantwana: 15 ukuya ku-40
• Abantu abadala: 45 ukuya ku-130

Iaspartic acid:

• Abantwana: 0 ukuya kuma-26
• Abantu abadala: 0 kuye ku-6

Beta-alanine:

• Abantwana: 0 ukuya kuma-49
• Abantu abadala: 0 kuye kwi-29

I-beta-amino-isobutyric acid:

• Bantwana: ayifumaneki
• Abantu abadala: akafumaneki

ICarnosine:

• Bantwana: ayifumaneki
• Abantu abadala: akafumaneki

ICitrulline:

• Abantwana: 16 ukuya ku-32
• Abantu abadala: 16-55

Umqala:

• Abantwana: 19 ukuya ku-47
• Abantu abadala: 30 ukuya ku-65

I-Glutamic acid:

• Abantwana: 32 ukuya ku-140
• Abantu abadala: 18 ukuya ku-98

Glutamine:

• Abantwana: 420 ukuya ku-730
• Abantu abadala: 390-650

IGlycine:

• Abantwana: 110 ukuya ku-240
• Abantu abadala: 170 ukuya ku-330

Imbali:

• Abantwana: 68 ukuya kwi-120
• Abantu abadala: 26 ukuya kwi-120

IHydroxyproline:

• Abantwana: 0 ukuya ku-5
• Abantu abadala: akafumaneki

Isoleucine:

• Abantwana: 37-140
• Abantu abadala: 42-100

Leucine:

• Abantwana: 70 ukuya ku-170
• Abantu abadala: 66-170

Lysine:

• Abantwana: 120 ukuya kuma-290
• Abantu abadala: 150 ukuya ku-220

Imethionine:

• Abantwana: 13 ukuya ku-30
• Abantu abadala: 16-30

1-methylhistidine:

• Bantwana: ayifumaneki
• Abantu abadala: akafumaneki

3-methylhistidine:

• Abantwana: 0 ukuya kuma-52
• Abantu abadala: 0 ukuya ku-64

I-Ornithine:

• Abantwana: 44-90
• Abantu abadala: 27 ukuya ku-80

Iphenylalanine:

• Abantwana: 26 ukuya kuma-86
• Abantu abadala: 41-68

I-Phosphoserine:

• Abantwana: 0 ukuya ku-12
• Abantu abadala: 0 ukuya ku-12

Iphosphoethanolamine:

• Abantwana: 0 ukuya ku-12
• Abantu abadala: 0-55

Iproline:

• Abantwana: 130 ukuya kuma-290
• Abantu abadala: 110 ukuya ku-360

ISerine:

• Abantwana: 93-150
• Abantu abadala: 56-140

Taurine:

• Abantwana: 11 ukuya kwi-120
• Abantu abadala: 45 ukuya ku-130

Threonine:

• Bantwana: 67-150
• Abantu abadala: 92 ukuya ku-240

Ityrosine:

• Bantwana: 26-110
• Abantu abadala: 45 ukuya ku-74

Xabiso:

• Abantwana: 160 ukuya ku-350
• Abantu abadala: 150-310

Imizekelo engentla ibonisa imilinganiselo eqhelekileyo yeziphumo zolu vavanyo. Ezinye iilabhoratri zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo.

Ukunyuka kwenqanaba lilonke leamino acid egazini kunokuba ngenxa:

• Eclampsia
• Isiphoso esizelwe kwimetabolism
• Ukunganyamezelani kweFructose
• I-Ketoacidosis (kwisifo seswekile)
• Ukungaphumeleli kwezintso
• Isifo seReye
• Impazamo yaselebhu

Ukwehla kwenqanaba lilonke leamino acid egazini kunokubangelwa:

• Umsebenzi we-adrenal cortical hyperfunction
• Ifiva
• Isifo sehartnup
• Isiphoso esizelwe kwimetabolism
• Huntington chorea
• Ukungondleki
• Isifo seNephrotic
• Umkhuhlane kaPhlebotomus
• Irheumatoid Arthritis
• Impazamo yaselebhu

Ixabiso eliphezulu okanye eliphantsi le-amino acid kufuneka ithathelwe ingqalelo nolunye ulwazi. Iziphumo ezingaqhelekanga zinokubangelwa kukutya, iingxaki zofuzo, okanye iziphumo zeyeza.

Ukuhlola iintsana ngokwanda kwamanqanaba ee-amino acid kunokunceda ekufumaneni iingxaki kwimetabolism. Unyango kwangoko kwezi meko lunokuthintela iingxaki kwixa elizayo.

Uvavanyo lwee-amino acid

• Ii-amino acid

Ukutya DJ. Ii-amino acid, iipeptides, kunye neeproteni. Ku: Rifai N, ed. I-Tietz yeNcwadi yeKlinikhi yeKhemistry kunye neDiagnostics yeMolekyuli. Umhla wesi-6. ISt Louis, MO: Elsevier; I-2018: isahluko 28.

IKliegman RM, iSt. Geme JW, iBlum NJ, i-Shah SS, iTasker RC, uWilson KM. Iziphene kwimetabolism yeeamino acid. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, ii-eds. Incwadi kaNelson yeNcwadi yePediatrics. Umhla wama-21. IPhiladelphia, PA: Elsevier; 2020: isahl. 103.

URiley RS, uMcPherson RA. Uvavanyo olusisiseko lomchamo. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 28.