Idlala lengqula yegazi le-peroxidase

IiMicrosomes zifumaneka ngaphakathi kweeseli zedlala lengqula. Umzimba uvelisa ii-antibodies kwii-microsomes xa kukho umonakalo kwiiseli ze-thyroid. Uvavanyo lwe-antithyroid microsomal antibody luthatha amanyathelo kwezi zintsholongwane egazini.

Isampulu yegazi iyafuneka.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

Olu vavanyo lwenziwa ukuqinisekisa unobangela weengxaki ze-thyroid, kuquka ne-Hashimoto thyroiditis.

Uvavanyo lukwasetyenziselwa ukufumanisa ukuba isifo somzimba okanye sokuzimela komzimba sonakalisa idlala lengqula.

Uvavanyo olubi luthetha ukuba iziphumo ziqhelekile.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Uvavanyo oluqinisekileyo lunokubangelwa:

• I-Granulomatous thyroiditis (i-immune reaction ye-thyroid gland edla ngokulandela isifo esiphezulu sokuphefumula)
• IHashimoto thyroiditis (impendulo yamajoni omzimba ngokuchasene ne-thyroid gland)

Amanqanaba aphezulu ezi zintsholongwane nawo adibene nomngcipheko owandayo:

• Ukuphuma kwesisu
• I-Preeclampsia (uxinzelelo lwegazi oluphezulu kunye neeprotheyini kumchamo emva kweveki yama-20 yokukhulelwa)
• Ukuzalwa ngaphambi kwexesha
• Ukusilela kokuchumisa kwi-vitro

Kubalulekile: Isiphumo esihle asisoloko sithetha ukuba unesifo se-thyroid okanye ufuna unyango lwe-thyroid. Isiphumo esihle sinokuthetha ukuba unethuba eliphezulu lokuphuhlisa isifo se-thyroid kwixesha elizayo. Oku kuhlala kunxulunyaniswa nembali yosapho yesifo se-thyroid.

Iintsholongwane ze-Antithyroid microsomal antibodies zinokubonwa kwigazi lakho ukuba unezinye iimeko ezizimeleyo, kubandakanya:

• I-anemia ye-hemolytic ezenzekelayo
• Ngokuzimela hepatitis
• Izifo ezizimeleyo ze-adrenal
• Irheumatoid Arthritis
• Isifo seSjögren
• Inkqubo ye lupus erythematosus

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Idlala elwa ntsholongwane; Antimicrosomal omzimba; Umzimba omncinci omncinci; Antithyroid microsomal antibody; TPOAb; Unyango-anti-TPO

• Uvavanyo lwegazi

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IChernecky CC, iBerger BJ. I-thyroid peroxidase (i-TPO, i-antimicrosomal antibody, i-antithyroid microsomal antibody) yegazi. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 1080-1081.

UGuber HA, uFarag AF. Uvavanyo lomsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; Ngo-2017: isahluko 24.

USalvatore D, uCohen R, uKopp PA, uLarsen PR. I-thyroid pathophysiology kunye novavanyo lokuqonda isifo. Ku: UMelmed S, uAuchus RJ, uGoldfine AB, uKoenig RJ, uRosen CJ, ii-eds. Incwadi kaWilliam ye-Endocrinology. Umhla we-14. IPhiladelphia, PA: Elsevier; 2020: isahl 11.

I-Weiss RE, Refetoff S. Umsebenzi wovavanyo lwe-thyroid. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, ii-eds. Endocrinology: Abantu abadala kunye nabantwana. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 78.