Inaliti yeFoscarnet

Umxholo

• Ngaphambi kokusebenzisa inaliti yefoscarnet,
• I-Foscarnet inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu libanda kungaquka oku kulandelayo:

IFoscarnet inokubangela iingxaki zezintso. Umngcipheko wokonzakala kwezintso mkhulu kubantu abaphelelwe ngamanzi emzimbeni. Ugqirha wakho uya kuyalela iimvavanyo zaselebhu ngaphambi kwaye ngexesha lonyango lwakho ukubona ukuba izintso zakho ziyachaphazeleka yileyeza. Xelela ugqirha wakho ukuba ukhe unesifo sezintso okanye unomlomo owomileyo, umchamo omnyama, ukubila okunciphile, ulusu olomileyo, kunye neminye imiqondiso yokuphelelwa ngamanzi emzimbeni okanye kutshanje, ukugabha, umkhuhlane, usulelo, ukubila kakhulu, okanye khange bakwazi ukusela ulwelo olwaneleyo. Xelela ugqirha wakho kunye nosokhemesti ukuba uthatha i-acyclovir (Zovirax); aminoglycoside antibiotics njenge-amikacin, kanamycin, neomycin, paromomycin, streptomycin, kunye ne-tobramycin; amphotericin (Abelcet, Ambisome); icyclosporine (Gengraf, Neoral, Sandimmune); imethotrexate (Otrexup, Rasuvo, Trexall); pentamidine (Nebupent, Pentam), okanye tacrolimus (Astagraf, Prograf). Ugqirha wakho usenokungafuni ukuba ufumane inaliti ye-foscarnet. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba ugqirha ngokukhawuleza: ukuncipha kokuchama; ukudumba kobuso, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi; ukudinwa okungaqhelekanga; okanye ubuthathaka.

IFoscarnet inokubangela ukuxhuzula. Tshela ugqirha wakho ukuba ukhe waxhuzula, wakha wanazo ezinye iingxaki zenkqubo yemithambo-luvo, okanye ukuba wakhe wanenqanaba eliphantsi le-calcium egazini lakho. Ugqirha wakho uya kujonga inqanaba le-calcium egazini lakho ngaphambi kokuba ufumane inaliti ye-foscarnet kwaye ngexesha lonyango. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, biza ugqirha ngoko nangoko: ukuxhuzula; ukuba ndindisholo okanye ukurhawuzelela umlomo okanye iminwe okanye iinzwane; ukukhawuleza, ukubetha, okanye ukubetha kwentliziyo okungaqhelekanga; okanye ukuphazamiseka kwemisipha.

Gcina lonke ixesha lokudibana nogqirha wakho, kubandakanya nogqirha wakho wamehlo, kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile, kubandakanya nokuhlolwa kwamehlo ngamaxesha athile, ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-foscarnet. Ugqirha wakho unokuyalela i-electrocardiogram (i-ECG; uvavanyo olulinganisa umsebenzi wombane entliziyweni) ngaphambi nangexesha lonyango lwakho.

Inaliti yeFoscarnet isetyenziswa yodwa okanye i-ganciclovir (iCytovene) ukunyanga i-cytomegalovirus (CMV) retinitis (usulelo lwamehlo olunokubangela ubumfama) kubantu abanentsholongwane kaGawulayo (HIV). Inaliti yeFoscarnet ikwasetyenziselwa ukunyanga usulelo lwe-herpes simplex virus (HSV) kulusu kunye neembumba zencindi (umlomo, umngxuma) kubantu amajoni omzimba angasebenziyo ngesiqhelo kwaye xa unyango nge-acyclovir lungancedi. IFoscarnet ikudidi lwamayeza abizwa ngokuba zii-antivirals. Isebenza ngokunciphisa ukukhula kwe-CMV kunye ne-HSV. I-Foscarnet ilawula i-CMV retinitis kunye nosulelo lwe-HSV kulusu kunye ne-mucus membranes kodwa ayizinyangi ezi zifo.

Inaliti yeFoscarnet iza njengolwelo oluza kungena ngaphakathi (emthanjeni). Ihlala inyanzeliswa kancinci ngaphezulu kweyure ukuya kwi-2 iiyure rhoqo emva kweeyure eziyi-8 okanye ezili-12. Ubude bonyango lwakho buxhomekeke kwindlela ophendula ngayo kunyango.

Unokufumana inaliti ye-foscarnet esibhedlele okanye unokuhambisa amayeza ekhaya. Ukuba uza kufumana inaliti ye-foscarnet ekhaya, umboneleli wakho wokhathalelo lwempilo uya kukubonisa indlela yokusebenzisa amayeza. Qiniseka ukuba uyayiqonda le ndlela, kwaye ubuze umboneleli wakho ukuba unemibuzo

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Inaliti yeFoscarnet ngamanye amaxesha isetyenziselwa ukunyanga nokukhusela usulelo lwe-CMV kwizigulana ezinentsholongwane yomntu (i-HIV). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa inaliti yefoscarnet,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-foscarnet, nawaphi na amanye amayeza, okanye nasiphi na isithako senaliti ye-foscarnet. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya amayeza adweliswe kwicandelo LESILUMKISO ESIBALULEKILEYO kunye nayiphi na kwezi zilandelayo: amiodarone (Cordarone, Nexterone, Pacerone); i-azithromycin (iZithromax); i-clarithromycin (i-Biaxin); i-diuretics ('iipilisi zamanzi') ezinjenge-bumetanide, i-ethacrynic acid (i-Edecrin), i-furosemide (i-Lasix), okanye i-torsemide (i-Demadex); dofetilide (iTikosyn); erythromycin (E-mycin, Ery-Tab, nabanye); i-fluoroquinolone antibiotics iquka i-ciprofloxacin (Cipro), gatifloxacin (Tequin), levofloxacin (Levaquin), moxifloxacin (Avelox), kunye ne-ofloxacin (Floxin); amayeza okugula ngengqondo okanye isicaphucaphu; ukuvelisa; quinidine (kwiNuedexta); i-ritonavir (iNorvir, eKaletra); i-saquinavir (i-Invirase); i-sotalol (iBetapace, iSorine); kunye ne-tricyclic antidepressants (’mood elevators’) ezinje ngeamitriptyline, desipramine (Norpramin), doxepin (Silenor), okanye nortriptyline (Pamelor). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana nenaliti ye-foscarnet, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba ukhe wanayo okanye wakha wanokwandiselwa ixesha le-QT (isingqisho sentliziyo esingaqhelekanga esinokukhokelela ekuphelelweni lithemba, ukuphulukana nokuqonda, ukuxhuzula, okanye ukufa ngesiquphe); amanqanaba asezantsi e-potassium okanye i-magnesium egazini lakho; isifo sentliziyo; okanye ukuba utya ukutya okunetyuwa encinci.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana inaliti ye-foscarnet, tsalela ugqirha wakho.
• Kuya kufuneka uyazi ukuba i-foscarnet inokukwenza wozele okanye ube nesiyezi. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Foscarnet inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• ukurhawuzelela, ukuba bomvu, iintlungu, okanye ukudumba kwindawo ofumene kuyo inaliti
• isicaphucaphu
• isisu esibuhlungu
• umqolo obuhlungu
• ukuphelelwa ngumdla wokutya okanye ubunzima
• ukuqhina
• intloko ebuhlungu
• utshintsho lombono
• ubomvu, ukucaphuka, okanye izilonda kwilungu lobudoda
• ubomvu, ukucaphuka, okanye izilonda ezijikeleze ubufazi

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• irhashalala
• urhwebo
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, okanye umqala
• ubunzima bokuphefumla okanye ukugwinya
• iintlungu zesifuba
• ngokukhawuleza, ukubetha, okanye ukubetha kwentliziyo okungaqhelekanga
• isiqaqa
• intloko elula
• ukulahleka kwengqondo
• ukugabha
• urhudo
• umkhuhlane, ukugodola, ukukhohlela, okanye ezinye iimpawu zosulelo
• ukopha okungaqhelekanga okanye ukugruzuka
• izitulo ezimnyama kunye nokulinda
• ukugabha kwegazi okanye into egabileyo ebonakala ngathi yindawo yekhofi
• ulusu oluthuthu
• ukuqhawukelwa ngumphefumlo
• ukudideka
• iintlungu zezihlunu okanye iicramps
• ukwanda kokubila

I-Foscarnet inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• ukuxhuzula
• ukuba ndindisholo okanye ukurhawuzelela umlomo okanye iminwe okanye iinzwane
• ukuncipha kokuchama
• ukudumba kobuso, iingalo, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa okungaqhelekanga okanye ubuthathaka

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Foscavir^®