Imatinib

Umxholo

• Ngaphambi kokuba uthathe imatinib,
• I-Imatinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Imatinib isetyenziselwa ukunyanga iintlobo ezithile ze-leukemia (umhlaza oqala kwiiseli ezimhlophe zegazi) kunye neminye imihlaza kunye nokuphazamiseka kweeseli zegazi. I-Imatinib ikwasetyenziselwa ukunyanga iintlobo ezithile zesisu esibuhlungu (GIST; uhlobo lwethumba olukhula kwiindonga zeendlela zokugaya kwaye zinokusasazeka ziye kwamanye amalungu omzimba). I-Imatinib ikwasetyenziselwa ukunyanga i-dermatofibrosarcoma protuberans (ithumba elenza phantsi kolusu oluphezulu) xa ithumba lingenakususwa ngotyando, lisasazeke kwamanye amalungu omzimba, okanye libuye emva kotyando. I-Imatinib ikwiklasi yamayeza abizwa ngokuba yi-kinase inhibitors. Isebenza ngokuthintela isenzo seprotein engaqhelekanga ebonisa iiseli zomhlaza ukuba zande. Oku kunceda ukunqanda ukusasazeka kweeseli zomhlaza.

I-Imatinib iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa ngokutya kunye neglasi enkulu yamanzi kube kanye okanye kabini ngemini. Thatha imatinib ngokujikeleza ixesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha imatinib ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ginya iipilisi ngokupheleleyo; sukuzihlafuna okanye uzityumze. Ukuba uchukumisa okanye unxibelelana ngokuthe ngqo nethebhulethi eyaphukileyo, hlamba loo ndawo ngocoselelo.

Ukuba awukwazi ukugwinya iipilisi ze-imatinib, unokubeka zonke iipilisi ozifunayo zedosi enye kwiglasi yamanzi okanye ijusi yeapile. Sebenzisa ii-milliliters ezingama-50 (ngaphantsi kwee-ounces ezi-2) zolwelo kwithebhulethi nganye ye-100-mg kunye neemililitha ezingama-200 (ngaphantsi kwee-ounces ezisixhenxe) zolwelo kwithebhulethi nganye engama-400-mg. Gcoba ngecephe de kube iipilisi ziwe ngokupheleleyo kwaye usele umxube kwangoko.

Ukuba ugqirha ukuxelele ukuba uthathe i-800 mg ye-imatinib, kuya kufuneka uthathe iipilisi ezimbini kwezingama-400-mg. Musa ukuthatha i-8 yeepilisi ze-100-mg. Ipeyinti yecwecwe iqulethe isinyithi, kwaye uya kufumana isinyithi kakhulu ukuba uthatha i-8 yeepilisi ze-100-mg.

Ugqirha wakho unokunyusa okanye anciphise idosi ye-imatinib ngexesha lonyango lwakho. Oku kuxhomekeke ekubeni lisebenza njani na iyeza nakwiziphumo ebezingalindelekanga ohlangabezana nazo. Thetha nogqirha wakho malunga nendlela oziva ngayo ngexesha lonyango lwakho. Qhubeka uthathe imatinib nokuba uziva uphilile. Sukuyeka ukuthatha imatinib ungakhange uthethe nogqirha wakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe imatinib,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-imatinib, nawaphi na amanye amayeza, okanye nasiphi na isithako kwiipilisi ze-imatinib. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha.Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: acetaminophen (Tylenol), alprazolam (Xanax), amlodipine (Norvasc, eCaduet, Lotrel, Tribenzor, abanye), atazanavir (Reyataz), atorvastatin (Lipitor, eCaduet), carbamazepine (Carbatrol, I-Equetro, iTegretol, abanye), i-clarithromycin (i-Biaxin, kwi-Prevpac), i-cyclosporine (i-Gengraf, i-Neoral, i-Sandimmune), i-dexamethasone, i-ergotamine (i-Ergomar, e-Migergot, i-Cafergot), i-erythromycin (i-EES, i-Eryc, i-Eryipam, abanye), , fentanyl (Duragesic, Subsys, Fentora, abanye), fosphenytoin (Cerebyx), indinavir (Crixivan), isinyithi, okanye isinyithi esinezincedisi, isradipine, itraconazole (Onmel, Sporanox), ketoconazole, lovastatin (Altoprev), metoprolol (Lopoprol) XL, kwiDutoprol), nefazodone, nelfinavir (Viracept), nicardipine (Cardene), nifedipine (Adalat CC, Procardia, abanye), nimodipine (Nymalize), nisoldipine (Sular), oxcarbazepine (Oxtellar XR, Trileptal), phenyarinital (phenobarbital) Dilantin, Phenytek), pimozide (Orap), primidone (Mysoline), qui nidine (eNuedexta), rifabutin (Mycobutin), rifampin (rifadin, rimactane, eRifamate, Rifater), ritonavir (Norvir, e Kaletra, Technivie, Viekira), saquinavir (Fortovase, Invirase), simvastatin (Zocor, sirolimus (Rapamune), tacrolimus (Astagraf XL, Envarsus XR, Prograf), telithromycin, triazolam (Halcion), voriconazole (Vfend), kunye warfarin (Coumadin, Jantoven). Amanye amayeza amaninzi anokusebenzisana ne-imatinib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba wakhe wanentliziyo, imiphunga, idlala lengqula, izintso, okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Kuya kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuqala unyango, akufuneki ukhulelwe ngelixa uthatha imatinib kunye neentsuku ezili-14 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwa ngelixa uthatha imatinib, tsalela ugqirha wakho. I-Imatinib inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngelixa uthatha i-imatinib kunye nenyanga enye emva kwedosi yakho yokugqibela.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha imatinib.
• Kuya kufuneka uyazi ukuba imatinib inokukwenza ube nesiyezi, uzele, okanye ubangele umbono ophuthileyo. Musa ukuqhuba imoto okanye usebenzise oomatshini de ube uyazi indlela elikuchaphazela ngayo eli yeza.

Musa ukuyitya i-grapefruit okanye usele ijusi yeziqhamo ngelixa uthatha eli yeza.

Thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Imatinib inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• isicaphucaphu
• ukugabha
• utshintsho kwindlela izinto ezingcamla ngayo
• izilonda zomlomo okanye ukudumba ngaphakathi emlonyeni
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• Isitshisa okanye isisu
• umlomo owomileyo
• intloko ebuhlungu
• ukudumba ngokudibeneyo okanye iintlungu
• iintlungu zethambo
• izihlunu, izihlunu, okanye iintlungu
• ukurhawuzelela, ukutsha. okanye ukuziva urhawuzelela ulusu
• ubunzima bokulala okanye ukulala
• ukubila
• Amehlo aneenyembezi
• iliso elipinki
• ukugungxula
• isikhumba esomileyo
• irhashalala
• ukurhawuzelela
• iinzipho utshintsho
• ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu biza ugqirha ngokukhawuleza:

• ukudumba ujikeleze amehlo
• ukudumba kwezandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukukhawuleza ukutyeba
• ukuqhawukelwa ngumphefumlo
• ngokukhawuleza, ngokungaqhelekanga, okanye ukubetha kwentliziyo
• ukukhohlela upinki okanye i-mucus enegazi
• ukwanda komchamo, ngakumbi ebusuku
• iintlungu zesifuba
• ukuxobuka, ukudubula, okanye ukuchitha ulusu
• mthubi ulusu okanye amehlo
• igazi esitulweni
• ukugruzuka okanye ukopha okungaqhelekanga
• Iimpawu ezinjengomkhuhlane, umqala obuhlungu, umkhuhlane, ukugodola kunye neminye imiqondiso yosulelo
• ukudinwa kakhulu okanye ubuthathaka
• iintlungu esiswini okanye ukudumba

I-Imatinib inokucothisa ukukhula kubantwana. Ugqirha womntwana wakho uya kujonga ukukhula kwakhe ngononophelo. Thetha nogqirha womntwana wakho malunga neengozi zokunika imatinib kumntwana wakho.

I-Imatinib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isicaphucaphu
• ukugabha
• urhudo
• irhashalala
• ukudumba
• ukudinwa kakhulu
• izihlunu okanye izihlunu
• intlungu zesisu
• intloko ebuhlungu
• Ukuphelelwa ngumdla wokutya

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-imatinib.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Gleevec^®