Inaliti ye-Ondansetron

Umxholo

• Ngaphambi kokusebenzisa i-ondansetron,
• I-Ondansetron inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufune unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Inaliti ye-Ondansetron isetyenziselwa ukuthintela isicaphucaphu kunye nokugabha okubangelwa ngumhlaza chemotherapy kunye notyando. I-Ondansetron ikudidi lwamayeza abizwa ngokuba yi-serotonin 5-HT₃ abachasi be-receptor. Isebenza ngokuthintela isenzo se-serotonin, into yendalo enokubangela isicaphucaphu nokugabha.

I-Ondansetron iza njengesisombululo (ulwelo) sokutofelwa ngaphakathi (emthanjeni) okanye nge-intramuscularly (kwisihlunu) ngumboneleli wezempilo esibhedlele okanye ekliniki. Xa i-ondansetron isetyenziselwa ukuthintela isicaphucaphu kunye nokugabha okubangelwe yichemotherapy, ihlala inikwa imizuzu engama-30 ngaphambi kokuqala kwekhemotherapy. Amayeza ongezelelweyo anokunikwa kwiiyure ezi-4 emva kwethamo lokuqala le-ondansetron kunye neeyure eziyi-8 emva kwethamo lokuqala le-ondansetron, ukuba kukho imfuneko. Xa i-ondansetron isetyenziselwa ukuthintela isicaphucaphu kunye nokugabha okubangelwa lutyando, ihlala inikwa kanye phambi koqhaqho. I-Ondansetron ngamanye amaxesha inikwa emva kotyando kwizigulana ezifumana isicaphucaphu nokugabha kwaye ezingakhange zifumane i-ondansetron ngaphambi kotyando.

La mayeza angamiselwa ezinye izinto. Buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-ondansetron,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa i-ondansetron, i-alosetron (Lotronex), i-dolasetron (i-Anzemet), i-granisetron (i-Kytril), i-palonosetron (i-Aloxi), okanye nawaphi na amanye amayeza: okanye naziphi na izithako kwi-ondansetron injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba ufumana iapomorphine (Apokyn). Ugqirha wakho uya kukuxelela ukuba ungasebenzisi i-ondansetron ukuba ufumana eli yeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: amiodarone (Cordarone, Pacerone); i-azithromycin (iZithromax); amayeza athile okubanjwa afana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), okanye phenytoin (Dilantin); chloroquine (Aralen); chlorpromazine; ikitalopram (uCelexa); i-clarithromycin (i-Biaxin, kwi-Prevpac); umchamo ('iipilisi zamanzi'); erythromycin (EES, Erythrocin, abanye); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Onsolis, Subsys); flecainide; haloperidol (iHaldol); lithium (Lithobid); amayeza ukunyanga i-migraines efana ne-almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), kunye zolmitriptan (Zomig); imethylene eluhlaza okwesibhakabhaka; i-mirtazapine (iRemeron); I-monoamine oxidase (MAO) inhibitors kubandakanya isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kunye ne-tranylcypromine (iParnate); moxifloxacin (Avelox); ipentamidine (Nebu-Pent); ipimozide (Orap); ukuvelisa; quinidine; irifampin (Rifadin, Rimactane, eRifamate, eRifater); i-serotonin / norepinephrine reuptake inhibitors (SNRIs) enje nge-desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), kunye ne-venlafaxine (Effexor XR); i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo njenge-citalopram (i-Celexa), i-escitalopram (i-Lexapro), i-fluoxetine (i-Prozac, i-Sarafem, kwi-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) kunye ne-sertraline (i-Zoloft); i-sotalol (iBetapace, iSorine); thioridazine; tramadol (Conzip, Ultram, kwi-Ultracet); kunye ne-vandetanib (Caprelsa). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akujonge ngononophelo kwiziphumo ebezingalindelekanga. Amanye amayeza amaninzi anokusebenzisana ne-ondansetron, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba wena okanye omnye umntu kusapho lwakho une-QT syndrome (imeko eyonyusa umngcipheko wokuba nesifo sentliziyo esingaqhelekanga esinokubangela ukuba utyhafile okanye usweleke ngesiquphe), okanye olunye uhlobo lokubetha kwentliziyo okungaqhelekanga okanye ingxaki yesingqisho sentliziyo, okanye ukuba unayo okanye wakhe wanamaqondo asezantsi e-magnesium okanye i-potassium egazini lakho, ukusilela kwentliziyo (HF; imeko apho intliziyo ingakwazi ukumpompa igazi elaneleyo kwamanye amalungu omzimba), okanye isifo sesibindi.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwa ngelixa ufumana i-ondansetron, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

I-Ondansetron inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• intloko ebuhlungu
• ukuqhina
• ukozela
• uziva ubanda okanye ubanda
• iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha esandleni okanye ezinyaweni
• ifiva
• iintlungu kwindawo yenaliti, ukuba bomvu, ukudumba, ukufudumala, okanye ukutshisa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko okanye ufune unyango olungxamisekileyo:

• irhashalala
• urhwebo
• ukurhawuzelela
• ukudumba kwamehlo, ubuso, imilebe, ulwimi, umqala, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukudinwa
• ubunzima bokuphefumla okanye ukugwinya
• iintlungu zesifuba
• ukuqhawukelwa ngumphefumlo
• utywala, intloko-elula, okanye ukuphelelwa amandla
• ukukhawuleza, ukukhawuleza okanye ukungahambi kakuhle kwentliziyo
• ukungaboni kakuhle okanye ukulahleka kombono
• intloko elula
• ukuphazamiseka
• ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho)
• ifiva
• ukubila okugqithisileyo
• ukudideka
• isicaphucaphu, ukugabha, okanye urhudo
• ukulahleka koququzelelo
• izihlunu eziqinileyo okanye ezijijekileyo
• ukuxhuzula
• isiqaqa (ukulahleka kwengqondo)

I-Ondansetron inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Eli yeza liza kugcinwa esibhedlele okanye eklinikhi.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukulahleka ngokukhawuleza kombono ixesha elifutshane
• utywala okanye intloko
• isiqaqa
• ukuqhina
• ukubetha kwentliziyo ngendlela engaqhelekanga

Gcina lonke ixesha lokudibana nogqirha wakho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Zofran^® Inaliti