IBortezomib

Umxholo

• Ngaphambi kokusebenzisa i-bortezomib,
• I-Bortezomib inokubangela iziphumo ebezingalindelekanga. Xelela ugqirha wakho ukuba ngaba kukho enye yezi mpawu, okanye ezo zikwicandelo LOKUGCINWA KUKHETHEKILEYO, zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:
• Iimpawu libanda kungaquka oku kulandelayo:

I-Bortezomib isetyenziselwa ukunyanga abantu abane-myeloma eninzi (uhlobo lomhlaza womongo wethambo). I-Bortezomib isetyenziselwa ukunyanga abantu abane-mantle cell lymphoma (umhlaza okhula ngokukhawuleza oqala kwiiseli zomzimba). I-Bortezomib ikudidi lwamayeza abizwa ngokuba zii-antineoplastic agents. Isebenza ngokubulala iiseli zomhlaza.

I-Bortezomib iza njengesisombululo (ulwelo) ukujova emthanjeni okanye ngaphantsi (phantsi kolusu). IBortezomib inikwa ngugqirha okanye ngumongikazi kwiofisi yezonyango okanye eklinikhi. Ishedyuli yakho yokulinganisa iya kuxhomekeka kwimeko onayo, amanye amayeza owasebenzisayo, kunye nendlela ophendula ngayo emzimbeni wakho kunyango.

Qiniseka ukuba uxelela ugqirha wakho indlela oziva ngayo ngexesha lonyango lwakho. Ugqirha wakho angayeka unyango lwakho okwethutyana okanye anciphise idosi yakho ye-bortezomib ukuba ufumana iziphumo ebezingalindelekanga zonyango.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-bortezomib,

• xelela ugqirha wakho kunye nomboneleli wezempilo ukuba ngaba u-aleji kwi-bortezomib, mannitol, nawaphi na amanye amayeza, i-boron, okanye nasiphi na isithako esikwibortezomib. Buza umboneleli wakho wezempilo uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, okanye izongezo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: clarithromycin (Biaxin, kwi-PrevPac); ii-antifungals ezithile ezinje nge-itraconazole (Sporanox) okanye ketoconazole (Nizoral); idelalisib (iZydelig); amayeza okunyanga isifo seswekile okanye uxinzelelo oluphezulu lwegazi; amayeza athile okunyanga intsholongwane kaGawulayo (i-HIV) okanye i-immunodeficiency syndrome (i-AIDS) efana ne-indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), okanye saquinavir (Invirase); amayeza athile okunyanga ukuxhuzula okunje nge-carbamazepine (Carbatrol, Tegretol), phenobarbital (Luminal, Solfoton), okanye phenytoin (Dilantin, Phenytek); nefazodone; I-ribociclib (Kisqali, Kisqali, kwiFemera); irifabutin (Mycobutin); okanye i-rifampin (Rifadin, Rifamate, Rimactane, abanye). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga. Uninzi lwamanye amayeza anokusebenzisana ne-bortezomib, ke qiniseka ukuxelela ugqirha wakho ngawo onke amayeza owathathayo, nkqu nalawo angaveli kolu luhlu.
• xelela ugqirha wakho ukuba zeziphi iimveliso zemithi ozithathayo, ngakumbi iSt John's wort.
• xelela ugqirha wakho ukuba wena okanye nabani na kusapho lwakho unesifo sentliziyo kwaye ukuba unesifo se-herpes (izilonda ezibandayo, amaqhuma, okanye izilonda zangasese); isifo seswekile; isiqaqa; i-cholesterol ephezulu (amafutha egazini); uxinzelelo lwegazi oluphantsi okanye oluphezulu; i-peripheral neuropathy (ukuba ndindisholo, iintlungu, ukurhawuzelela, okanye ukuvutha ezinyaweni okanye ezandleni) okanye ubuthathaka okanye ukulahleka kwemvakalelo okanye ingqondo kwingxenye yomzimba wakho; okanye isifo sezintso okanye sesibindi. Xelela ugqirha wakho ukuba uyatshaya okanye usele izixa ezikhulu zotywala.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. I-Bortezomib inokulimaza umbungu. Sebenzisa ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye ne-bortezomib kwaye ubuncinci iinyanga ezisi-7 emva kwedosi yakho yokugqibela. Ukuba uyindoda eneqabane lomfazi onokukhulelwa, qiniseka ukusebenzisa ulawulo lokuzalwa ngexesha lonyango lwakho kunye ne-bortezomib kwaye ubuncinci iinyanga ezi-4 emva kwedosi yakho yokugqibela. Buza ugqirha wakho ukuba unemibuzo malunga nohlobo lolawulo lokuzalwa oluza kukusebenzela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa usebenzisa i-bortezomib okanye iinyanga ezisi-7 emva kwedosi yakho yokugqibela, tsalela ugqirha wakho kwangoko.
• ungancancisi ngexesha lonyango lwakho kunye ne-bortezomib kunye neenyanga ezi-2 emva kwedosi yakho yokugqibela.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-bortezomib.
• Kuya kufuneka uyazi ukuba i-bortezomib inokukwenza wozele, ube nesiyezi, okanye ube nentloko elula, okanye ubangele ukuba utyhafile okanye ungaboni kakuhle. Sukuqhuba imoto okanye usebenzise oomatshini okanye izixhobo eziyingozi de ube uyazi indlela ekuchaphazela ngayo la mayeza.
• Kuya kufuneka uyazi ukuba i-bortezomib inokubangela ukuba ube nesiyezi, ubukrwada, kwaye utyhafe xa usukuma ngokukhawuleza kwindawo yokulala. Oku kuqheleke kakhulu kubantu abaphelelwe ngamandla ngaphambili, abantu abaphelelwe ngamanzi emzimbeni, nabantu abathatha amayeza anciphisa uxinzelelo lwegazi. Ukuthintela le ngxaki, phuma kancinci ebhedini, uphumle iinyawo zakho phantsi imizuzu embalwa ngaphambi kokuba ume.

Thetha nogqirha wakho malunga nokutya igrapefruit kunye nokusela ijusi yegrapefruit ngelixa usebenzisa eli yeza.

Phuza amanzi amaninzi yonke imihla ngexesha lonyango lwakho nge-bortezomib, ngakumbi ukuba uyagabha okanye unorhudo.

Ukuba uphoswa ukuqeshwa ukuze ufumane idosi ye-bortezomib, tsalela ugqirha wakho kwangoko.

I-Bortezomib inokubangela iziphumo ebezingalindelekanga. Xelela ugqirha wakho ukuba ngaba kukho enye yezi mpawu, okanye ezo zikwicandelo LOKUGCINWA KUKHETHEKILEYO, zinzima okanye azihambi:

• ubuthathaka ngokubanzi
• ukudinwa
• isicaphucaphu
• ukugabha
• urhudo
• ukuqhina
• Ukuphelelwa ngumdla wokutya
• isisu esibuhlungu
• intloko ebuhlungu
• intlungu, ubomvu, ukutyumka, ukopha, okanye ubunzima kwindawo yenaliti
• ubunzima bokulala okanye ukulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ubuthathaka kwiingalo okanye emilenzeni, utshintsho kwindlela yokubamba, okanye iintlungu, ukutshisa, ukuba ndindisholo, okanye ukubetha ezandleni, iingalo, imilenze, okanye iinyawo.
• ukudubula ngequbuliso okanye ukuhlaba iintlungu, iintlungu ezingapheliyo okanye iintlungu ezivuthayo, okanye ubuthathaka bemisipha
• ukuphefumla okufutshane, ukubetha kwentliziyo okukhawulezayo, intloko ebuhlungu, isiyezi, ulusu olukhanyayo, ukudideka, okanye ukudinwa
• ukudumba kweenyawo, amaqatha okanye imilenze esezantsi
• urhashalala, irhashalala, ukurhawuzelela
• ukudumba, ubunzima bokuginya okanye ukuphefumla, okanye ukudumba kobuso, umqala, ulwimi, imilebe, amehlo, okanye izandla
• umkhuhlane, umqala obuhlungu, ingqele, ukukhohlela okanye ezinye iimpawu zosulelo
• ukugruzuka okanye ukopha okungaqhelekanga
• izitulo ezimnyama kunye nokulinda, igazi elibomvu ilindle, ukugabha kwegazi, okanye ukugabha okubonakala ngathi yindawo yekofu
• intetho edibeneyo okanye ukungakwazi ukuthetha okanye ukuqonda intetho, ukudideka, ukukhubazeka (ukulahleka kwamandla okuhambisa ilungu lomzimba), utshintsho lombono, okanye ukulahleka kombono, ukulinganisela, ukulungelelaniswa, imemori okanye ukuqonda
• Ukuphelelwa ngamandla, ukungaboni kakuhle, ukuba nesiyezi, isicaphucaphu, okanye izihlunu
• uxinzelelo lwesifuba okanye iintlungu, ukubetha kwentliziyo okukhawulezayo, ukudumba kwamaqatha okanye iinyawo, okanye ukuphefumla kancinci
• ukukhwehlela, ukuphefumla kancinci, ukuvutha, okanye ukuphefumla nzima
• intloko, ukudideka, ukuxhuzula, ukudinwa, okanye ukulahleka kombono okanye utshintsho
• amachaphaza amfusa abomvu ngaphantsi kolusu, umkhuhlane, ukudinwa, isiyezi, ukuphefumla kancinci, ukugruzuka, ukudideka, ukulala, ukuxhuzula, ukunciphisa ukuchama, igazi kumchamo, okanye ukudumba kwemilenze
• umkhuhlane, intloko ebuhlungu, ukugodola, isicaphucaphu, iintlungu, ukurhawuzelela okanye ukurhawuzelelwa kulandelwa kukuqhawuka kwindawo enye kunye namadyungudyungu esikhumba arhawuzayo okanye abuhlungu
• isicaphucaphu, ukudinwa kakhulu, ukopha okungaqhelekanga okanye ukugruzuka, ukunqongophala kwamandla, ukuphelelwa ngumdla wokutya, iintlungu kwinxalenye ephezulu yesisu, ukuba tyheli kolusu okanye amehlo, okanye iimpawu ezinje ngomkhuhlane

I-Bortezomib inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

IBortezomib iya kugcinwa kwiofisi yezonyango okanye eklinikhi.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

• isiqaqa
• isiyezi
• ukungaboni kakuhle
• ukugruzuka okanye ukopha okungaqhelekanga

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-bortezomib.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Velcade^®