Inaliti yeSipuleucel-T

Umxholo

• Ngaphambi kokufumana inaliti ye-sipuleucel-T,
• Inaliti ye-Sipuleucel-T inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

Inaliti ye-Sipuleucel-T isetyenziselwa ukunyanga iintlobo ezithile zomhlaza wedlala lesinyi. Inaliti ye-Sipuleucel-T ikudidi lwamayeza abizwa ngokuba yi-autologous cellular immunotherapy, uhlobo lonyango olulungiselelwe kusetyenziswa iiseli ezivela kwigazi lesigulana. Isebenza ngokubangela amajoni omzimba (iqela leeseli, izicwili, kunye namalungu akhusela umzimba ekuhlaselweni ziintsholongwane, iintsholongwane, iiseli zomhlaza, kunye nezinye izinto ezibangela izifo) ukuba zilwe neeseli zomhlaza.

Inaliti ye-Sipuleucel-T iza njengokunqunyanyiswa (ulwelo) ukujova ngaphezulu kwemizuzu engama-60 emthanjeni ngugqirha okanye ngumongikazi kwiofisi kagqirha okanye kwiziko lokumnika. Ihlala inikwa kube kanye kwiiveki ezi-2 iyonke ngeedosi ezintathu.

Malunga neentsuku ezi-3 ngaphambi kokuba kunikwe inaliti nganye yesipuleucel-T, iisampulu zeeseli ezimhlophe zegazi ziya kuthathwa kwiziko lokuqokelela iiseli kusetyenziswa inkqubo ebizwa ngokuba yileukapheresis (inkqubo esusa iiseli ezimhlophe zegazi emzimbeni). Le nkqubo iya kuthatha malunga neeyure ezi-3 ukuya kwezi-4. Isampulu iya kuthunyelwa kumenzi kwaye idityaniswe neprotein ukulungiselela idosi yesipuleucel-T inaliti. Ngenxa yokuba eli yeza lenziwe kwiiseli zakho, liya kunikwa wena kuphela.

Thetha nogqirha wakho malunga nendlela yokulungiselela i-leukapheresis kunye nento onokuyilindela ngexesha nasemva kwenkqubo. Ugqirha wakho uza kukuxelela into ekufuneka uyidle kwaye uyisele kwaye kufuneka uyiphephe ngaphambi kwenkqubo. Unokuba neziphumo ebezingalindelekanga, ezinje ngesiyezi, ukudinwa, ukurhawuzelela iminwe okanye ujikeleze umlomo, uziva ubanda, uphelelwe ngamandla, kunye nesicaphucaphu ngexesha lenkqubo. Ungaziva udiniwe emva kwenkqubo, ke unokufuna ukucwangcisela umntu oza kukuqhubela ekhaya.

Inaliti ye-Sipuleucel-T kufuneka inikwe zingadlulanga iintsuku ezi-3 ukusukela kwixesha eyayilungiselelwe ngalo. Kubalulekile ukufika ngexesha kwaye ungaphoswa nayiphina indawo ebekiweyo yokuqokelelwa kweseli okanye ukufumana idosi nganye yonyango.

Inaliti ye-Sipuleucel-T inokubangela ukusabela okunobuzaza ngexesha lokufakwa kunye nemizuzu engama-30 emva koko. Ugqirha okanye umongikazi uya kukujonga ngeli xesha ukuze aqiniseke ukuba awunampendulo imbi kunyango. Uya kunikwa amanye amayeza kwimizuzu engama-30 ngaphambi kokufakwa kwakho ukuthintela iimpendulo kwisitofu se-sipuleucel-T. Xelela ugqirha wakho okanye umongikazi kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo: isicaphucaphu, ukugabha, ukugodola, umkhuhlane, ukudinwa kakhulu, isiyezi, ukuphefumla nzima, ukukhawuleza kwentliziyo okanye ukubetha kwentliziyo ngendlela engaqhelekanga, okanye iintlungu esifubeni.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-sipuleucel-T,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa inaliti ye-sipuleucel-T, nawaphi na amanye amayeza, okanye nasiphi na isithako esisejeniseni le-sipuleucel-T. Buza usokhemesti wakho okanye ugqirha okanye ujonge ulwazi lomenzi wesigulana uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya oku kulandelayo: amanye amayeza achaphazela amajoni omzimba afana ne-azathioprine (Imuran); i-cyclosporine (iNeoral, iSandimmune); amayeza omhlaza; imethotrexate (Rheumatrex); i-steroids yomlomo efana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (Medrol), i-prednisolone, kunye ne-prednisone (Deltasone); i-sirolimus (iRapamune); kunye netacrolimus (Prograf).
• xelela ugqirha wakho ukuba ukhe wahlaselwa sistroke okanye isifo sentliziyo okanye semiphunga.
• Kuya kufuneka uyazi ukuba i-sipuleucel-T isebenza kuphela emadodeni.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphosa ixesha lokuqokelela iiseli zakho, kuya kufuneka ubize ugqirha wakho kunye neziko lokuqokelela kwangoko. Ukuba uphoswa idinga lokufumana inaliti ye-sipuleucel-T, kuya kufuneka ubize ugqirha ngoko nangoko. Kuya kufuneka uphinde inkqubo yokuqokelela iiseli zakho ukuba idosi elungiselelwe i-sinduleucel-T yenaliti iya kuphelelwa ngaphambi kokuba inikwe wena.

Inaliti ye-Sipuleucel-T inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• Ukugodola
• ukudinwa okanye ubuthathaka
• intloko ebuhlungu
• umqolo okanye iintlungu ezidibeneyo
• iintlungu zemisipha okanye ukuqina
• ukushukuma okungalawulekiyo kwilungu lomzimba
• ukubila

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana nayiphi na le mpawu, biza ugqirha wakho ngokukhawuleza:

• ububomvu okanye ukudumba kufutshane nendawo yolusu apho ubungenise khona okanye apho iiseli zaqokelelwa khona
• Umkhuhlane ongaphezulu kwe-100.4 ° F (38 ° C)
• intetho ecothayo okanye enzima
• isiyezi okanye ukudinwa ngesiquphe
• ubuthathaka okanye ukuba ndindisholo kwengalo okanye umlenze
• kunzima ukugwinya
• igazi kumchamo

Inaliti ye-Sipuleucel-T inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngexesha lonyango lwakho neli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho, indawo yokuqokelela iiseli, kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwisitofu se-sipuleucel-T.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Ukuzikhusela^®