Unokongeza

Umxholo

• Ngaphambi kokuba uthathe i-boceprevir,
• I-Boceprevir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

I-Boceprevir isetyenziswa kunye namanye amayeza amabini (i-ribavirin [i-Copegus, i-Rebetol] kunye ne-peginterferon alfa [Pegasys]) ukunyanga i-hepatitis C engapheliyo (usulelo lwentsholongwane oluqhubekayo olonakalisa isibindi) kubantu abangekanyangwa le meko okanye imeko ayikhange iphucule xa babephathwa nge-ribavirin kunye ne-peginterferon alfa yodwa. I-Boceprevir ikudidi lwamayeza abizwa ngokuba zii-protease inhibitors. Isebenza ngokunciphisa inani le-virus ye-hepatitis C (HCV) emzimbeni. I-Boceprevir ayinako ukuthintela ukusasazeka kwe-hepatitis C kwabanye abantu.

IBoceprevir iza njengephilisi emayithathwe ngomlomo. Ihlala ithathwa ngokutya okanye ukutya okulula okuncinci kathathu ngemini (zonke iiyure ezisi-7 ukuya kwezi-9). Thatha i-boceprevir kumaxesha afanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-boceprevir ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Uya kuthatha i-peginterferon alfa kunye ne-ribavirin iiveki ezi-4 ngaphambi kokuba uqale unyango nge-boceprevir. Emva koko uya kuthatha onke amayeza amathathu kwiiveki ezili-12 ukuya kwezi-44. Emva kweli xesha, uza kuyeka ukuthatha i-boceprevir, kodwa ungaqhubeka nokuthatha i-peginterferon alfa kunye ne-ribavirin ngenani elongezelelweyo leeveki. Ubude bonyango lwakho buxhomekeke kwimeko yakho, ukuba uphendula njani kunyango, kwaye nokuba uneziphumo ebezingalindelekanga ezibi. Qhubeka uthathe i-boceprevir, i-peginterferon alfa, kunye ne-ribavirin logama nje zimiselwe ngugqirha. Ungayeki ukuthatha nawaphi na amayeza ngaphandle kokuthetha nogqirha wakho nokuba uziva uphilile.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-boceprevir kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-boceprevir,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-boceprevir, nawaphi na amanye amayeza, okanye naziphi na izithako kwiifomsile ze-boceprevir. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho ukuba uthatha nawaphi na amayeza alandelayo okanye iimveliso zamayeza: alfuzosin (Uroxatral); amayeza e-ergot anje nge-dihydroergotamine (iDHE 45, Migranal), ergonovine, ergotamine (Ergomar, eCafergot, eMigergot) okanye i-methylergonovine; i-cisapride (Propulsid) (ayifumaneki e-U.S.); iDrospirenone (kwezinye izinto zokucwangcisa zomlomo ezinje ngeBeyaz, Gianvi, Ocella, Safyral, Yasmin, Yaz, kunye neZarah); I-lovastatin (Altoprev, Mevacor); amayeza athile okubanjwa afana ne-carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, okanye phenytoin (Dilantin); i-midazolam ethathwe ngomlomo; ipimozide (Orap); rifampin (Rifadin, Rimactane, kwiIsonaRif, eRifamate, eRifater); sildenafil (kuphela uphawu lweRevatio olusetyenziselwa isifo semiphunga); isimvastatin (Simcor, eVytorin); i-tadalafil (kuphela i-Adcirca brand esetyenziselwa isifo semiphunga); I-wort yaseSt. okanye i-triazolam (Halcion). Ugqirha wakho uya kukuxelela ukuba ungathathi i-boceprevir ukuba uthatha elinye okanye ngaphezulu kula mayeza.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo nolungabhaliswanga, iivithamini, kunye nezongezelelo zesondlo ozithathayo okanye oceba ukuzithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: alprazolam (Niravam, Xanax); ii-anticoagulants ('igazi elincinci)' njengewarfarin (Coumadin); amayeza okubola anje nge-itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), kunye ne-voriconazole (Vfend); atorvastatin (Lipitor, kwiCaduet); i-bosentan (iTracleer); budesonide (Pulmicort, Rhinocort, Symbicort); ibuprenorphine (iBuprenex, iButrans, iSubutex, iSuboxone); iicalcium block blockers ezinje ngefelodipine (Plendil), nicardipine (Cardene), kunye nifedipine (Adalat, Afeditab, Procardia); i-clarithromycin (i-Biaxin); icolchicine (Colcrys, kwiCol-Probenecid); icyclosporine (Gengraf, Neoral, Sandimmune); desipramine (Norpramin); dexamethasone; amayeza athile okungasebenzi kakuhle kwe-erectile njenge-sildenafil (Viagra), tadalafil (Cialis), kunye ne-vardenafil (Levitra, Staxyn); amayeza athile e-HIV afana ne-atazanavir athathwe nge-ritonavir, i-darunavir ethathwe nge-ritonavir, efavirenz (Sustiva, e-Atripla), lopinavir ethathwe nge-ritonavir, kunye ne-ritonavir (i-Norvir, e-Kaletra); amayeza athile okubetha kwentliziyo okungaqhelekanga afana ne-amiodarone (Cordarone, Pacerone), digoxin (Lanoxin), flecainide (Tambocor), propafenone (Rythmol), kunye nequinidine; imethadone (iDolophine, iMethadose); i-midazolam inikezwe ngaphakathi (kumthambo); irifabutin (Mycobutin); isalmeterol (iSerevent, eAdvair); i-sirolimus (iRapamune); itacrolimus (Prograf); kunye ne-trazodone. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wafakelwa ilungu elithile, kwaye ukuba unayo okanye wakha wanayo i-anemia (ayonelanga iiseli ezibomvu zegazi egazini ukuhambisa ioksijini kuwo wonke umzimba) i-syndrome (i-AIDS), nayiphi na imeko echaphazela amajoni akho omzimba, okanye i-hepatitis B (usulelo lwentsholongwane olonakalisa isibindi) okanye naluphi na uhlobo lwesifo sesibindi ngaphandle kwe-hepatitis C.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba uthatha i-boceprevir.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye unokukhulelwa. Ukuba uyindoda, xelela ugqirha wakho ukuba iqabane lakho likhulelwe, liceba ukukhulelwa, okanye kunokwenzeka ukuba ukhulelwe. I-Boceprevir kufuneka ithathwe nge-ribavirin enokwenzakalisa kakhulu umntwana ongekazalwa. Kuya kufuneka usebenzise iindlela ezimbini zolawulo lokuzalwa ukukhusela ukukhulelwa kuwe okanye kwiqabane lakho ngexesha lonyango kunye nala mayeza kunye neenyanga ezi-6 emva konyango lwakho. Thetha nogqirha wakho malunga neendlela onokuzisebenzisa; izinto zokucwangcisa zehomoni (iipilisi zolawulo lokuzalwa, iziqwengana, izinto zokufakelwa, imisesane, okanye inaliti) zisenokungasebenzi kakuhle kwabasetyhini abathatha la mayeza. Wena okanye iqabane lakho kufuneka nivavanyelwe ukukhulelwa inyanga nenyanga ngexesha lonyango kunye neenyanga ezi-6 emva konyango. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa uthatha la mayeza, biza ugqirha ngokukhawuleza.
• xelela ugqirha wakho ukuba uncelisa.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Thatha idosi ephosiweyo ngokutya nje ukuba ukhumbule. Nangona kunjalo, ukuba ziiyure ze-2 okanye ngaphantsi ngaphambi kwexesha elimiselweyo ledosi yakho elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Boceprevir inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• utshintsho kwisakhono sokungcamla
• Ukuphelelwa ngumdla wokutya
• ukudinwa kakhulu
• ubunzima bokulala okanye ukulala
• ukucaphuka
• ukulahleka kweenwele
• isikhumba esomileyo
• irhashalala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukuqhawukelwa ngumphefumlo
• isiyezi
• isiqaqa
• ubuthathaka
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo

I-Boceprevir inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Ungagcina iifomsile kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela) ukuya kuthi ga kwiinyanga ezintathu. Unako kwakhona ukugcina njengezingxobo efrijini de umhla wokuphelelwa eprintiweyo kwileyibhile idlulile. Lahla naliphi na iyeza eliphelelwe lixesha okanye elingasafunekiyo. Thetha kumachiza wakho malunga nokulahla ngokufanelekileyo amayeza akho.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi-boceprevir.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UnguVictrelis^®