Inaliti yePeginterferon Alfa-2b (iSylatron)

Umxholo

• Ngaphambi kokufaka inaliti ye-peginterferon alfa-2b,
• Inaliti ye-Peginterferon alfa-2b inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

Inaliti ye-Peginterferon alfa-2b ikwafumaneka njengemveliso eyahlukileyo (i-PEG-Intron) esetyenziselwa ukunyanga i-hepatitis C engapheliyo (ukudumba kwesibindi okubangelwa yintsholongwane). Le monograph inika kuphela ulwazi malunga nenaliti ye-peginterferon alfa-2b (iSylatron) esetyenziselwa ukunciphisa ithuba lokuba imelanoma enobungozi ibuye emva kotyando ukuyisusa. Ukuba usebenzisa i-Peg-Intron, funda i-monograph enesihloko esithi Peginterferon alfa-2b (PEG-Intron) ukufunda malunga nale mveliso.

Ukufumana inaliti ye-peginterferon alfa-2b kungonyusa umngcipheko wokuba ube neengxaki ezinzulu okanye ezisongela ubomi zempilo yengqondo, kubandakanya ukudakumba okunokubangela ukuba ucinge, ucwangcise, okanye uzame ukuzilimaza okanye uzibulale; i-psychosis (ubunzima bokucinga ngokucacileyo, ukuqonda ubunyani, ukunxibelelana nokuziphatha ngokufanelekileyo); kunye ne-encephalopathy (ukudideka, iingxaki zememori, kunye nobunye ubunzima obubangelwa kukungasebenzi kakuhle kwengqondo). Xelela ugqirha wakho ukuba ukhe wanengxaki yempilo yengqondo nokuba ukhe wacinga ngokuzenzakalisa okanye ukuzibulala. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko kugqirha: iimvakalelo zosizi okanye ukungabi nathemba; ukucinga, ukucwangcisa, okanye ukuzama ukuzibulala okanye ukuzenzakalisa; indlela yokuziphatha enengcwangu; ukudideka; iingxaki zememori; udidekile, yimincili engaqhelekanga; okanye ukubona izinto okanye ukuva amazwi engekhoyo. Qiniseka ukuba usapho lwakho okanye umntu okhathalelayo uyazi ukuba zeziphi iimpawu ezinokubanzima ukuze bakwazi ukufuna unyango ukuba awukwazi ukuzibiza ngokwakho.

Gcina lonke ixesha lokudibana nogqirha wakho. Ugqirha wakho uya kufuna ukuthetha nawe malunga nempilo yakho yengqondo ubuncinci kube kanye kwiiveki ezi-3 ekuqaleni konyango lwakho kwaye kube kanye kwiinyanga ezintandathu njengoko unyango lwakho luqhubeka. Ugqirha wakho angakuxelela ukuba uyeke ukusebenzisa inaliti ye-peginterferon alfa-2b ukuba uvelisa iimpawu zokugula ngengqondo. Nangona kunjalo, ukuba uhlakulela iingxaki zempilo yengqondo ngexesha lonyango lwakho, ezi ngxaki zinokungapheli xa uyeka ukufumana amayeza.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-peginterferon alfa-2b kwaye ngalo lonke ixesha uzalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti ye-peginterferon alfa-2b.

Inaliti ye-Peginterferon alfa-2b isetyenziswa kubantu abane-melanoma enobungozi (umhlaza osongela ubomi oqala kwiiseli ezithile zolusu) abaye batyandwa ukuze basuse umhlaza. Eli yeza lisetyenziselwa ukunciphisa ithuba lokuba imelanoma enobungozi ibuye kwaye kufuneka iqalwe ngaphakathi kweentsuku ezingama-84 zotyando. Inaliti yePeginterferon alfa-2b ikudidi lwamayeza abizwa ngokuba zii-interferon. Isebenza ngokumisa ukukhula kweeseli zomhlaza ukunciphisa ithuba lokuba imalanoma emibi ibuye.

Inaliti ye-Peginterferon alfa-2b iza njengomgubo wokudibanisa nolwelo olunikiweyo kunye nokujova (ngaphantsi kolusu). Ihlala itofwe kanye ngeveki ukuya kuthi ga kwiminyaka emi-5. Faka inaliti ye-peginterferon alfa-2b ngemini enye veki nganye. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Sebenzisa inaliti ye-peginterferon alfa-2b ngokuchanekileyo njengoko kuyalelwe. Musa ukuyitofa ngaphezulu okanye ngaphantsi okanye uyitofe rhoqo kunokuba umiselwe ngugqirha.

Ugqirha wakho uya kukuqalisa kwidosi ephezulu ye-peginterferon alfa-2b inaliti kwaye unciphise idosi yakho emva kweeveki ezisi-8. Ugqirha wakho unokunciphisa idosi yakho okanye akuxelele ukuba uyeke ukusebenzisa inaliti ye-peginterferon alfa-2b okwethutyana okanye ngokusisigxina ukuba uneziphumo ebezingalindelekanga ezibi.

Qhubeka nokusebenzisa inaliti ye-peginterferon alfa-2b nokuba uziva uphilile. Sukuyeka ukusebenzisa inaliti ye-peginterferon alfa-2b ngaphandle kokuthetha nogqirha wakho.

Unokujova i-peginterferon alfa-2b ngokwakho okanye umhlobo okanye isalamane sikunike inaliti. Wena kunye nomntu oza kufaka iyeza kufuneka ufunde izikhombisi zomenzi zokuxuba kunye nokujova iyeza ngaphambi kokuba ulisebenzise okokuqala ekhaya. Buza ugqirha wakho ukuba akubonise okanye umntu oza kuthi afake i-peginterferon alfa-2b indlela yokuxuba kunye nokuyifaka.

I-Peginterferon alfa-2b iza ikiti ebandakanya iisirinji ezifunekayo ukuxuba kunye nokujova iyeza. Sukusebenzisa naluphi na uhlobo lwesirinji ukuxuba okanye ukutofa amayeza akho. Musa ukwabelana okanye ukuphinda usebenzise iisirinji eziza nonyango lwakho. Lahla iinaliti, iisirinji kunye neebhotile kwisitya esinganyangekiyo emva kokuba uzisebenzise kwakanye. Buza ugqirha wakho okanye usokhemesti ngendlela yokusilahla isikhongozeli esinganyangekiyo.

Jonga ibhotile ye-peginterferon alfa-2b ngaphambi kokuba ulungiselele idosi yakho. Jonga ukuba ibhalwe igama elichanekileyo kunye namandla amayeza kunye nomhla wokuphelelwa kwayo ongadlulanga. Iyeza elikwibhotile linokujongeka njengepilisi emhlophe okanye emhlophe, okanye ithebhulethi inokuqhekeka ibe ziingceba okanye umgubo. Ukuba awunalo iyeza elifanelekileyo, iyeza lakho liphelelwe lixesha, okanye alijongeka ngendlela elifanele ngayo, tsalela usokhemesti wakho kwaye ungasisebenzisi eso sitya.

Kuya kufuneka uxube ibhotile enye ye-peginterferon alfa-2b ngexesha. Kungcono ukuxuba amayeza kanye phambi kokuba ucwangcise ukuwatofa. Nangona kunjalo, unokudibanisa amayeza kwangaphambili, uyigcine kwifriji, kwaye uyisebenzise ngaphakathi kweeyure ezingama-24. Ukuba ufuna ukufriji amayeza akho, qiniseka ukuba uyikhuphe kwifriji kwaye uyivumele ukuba ifike kubushushu begumbi ngaphambi kokuba uyijoje.

Unokujova naphi na emathangeni akho, umphezulu wengalo yakho ephezulu, okanye isisu sakho ngaphandle kwendawo ejikeleze inqanawa yakho okanye isinqe sakho. Ukuba ubhityile, akufuneki utofe iyeza kwindawo yesisu sakho. Khetha indawo entsha ngalo lonke ixesha utofa iyeza lakho. Musa ukujova nakweyiphi na indawo enomsindo, ibomvu, ityumkileyo, okanye yosulelekileyo okanye inezikrelemnqa, amaqhuma, okanye amanqaku wolule.

Unokufumana iimpawu ezinje ngomkhuhlane, ukugodola, iintlungu zemisipha, iintlungu ezidibeneyo, ukudinwa, kunye nentloko emva kokufaka inaliti ye-peginterferon alfa-2b. Ugqirha wakho uya kukuxelela ukuba uthathe i-acetaminophen (Tylenol) imizuzu engama-30 ngaphambi kokuba utofe idosi yakho yokuqala kwaye ngaphambi kokuba utofe idosi yakho elandelayo yenaliti ye-peginterferon alfa-2b. Ukujova iyeza lakho ngexesha lokulala kunokunceda ukunciphisa ezi mpawu. Qiniseka ukuba usele amanzi amaninzi xa unempawu ezinje ngomkhuhlane.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufaka inaliti ye-peginterferon alfa-2b,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabisa inaliti ye-peginterferon alfa-2b (PegIntron, Sylatron), i-interferon alfa-2b (Intron), nawaphi na amanye amayeza, okanye naziphi na izithako kwi-peginterferon alfa-2b injection. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhaliswanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha.Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: , Flector, Voltaren, abanye), duloxetine (Cymbalta), flecainide (Tambocor), fluvastatin (Lescol), glipizide (Glucotrol), haloperidol (Haldol), ibuprofen (Motrin), imipramine (Tofranil), irbesartan (Avapro), Cozaar), mexiletine, naproxen (Anaprox, Naprosyn), ondansetron (Zofran), paroxetine (Paxil, Pexeva), phenytoin (Dilantin), piroxicam (Feldene), propafenone (Rhythmol), risperidone (Risperdal), rosiganditazone (eBactrim, ngo-Septra), tamoxifen, thioridazine, timolol, tolbutamide, torsemide, tramadol (Conzip, Ultram, Ryzolt), venlafaxine (Effexor), kunye warfarin (Coumadin, Jantoven). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha wanesifo sokuqina kwesibindi (imeko apho iiseli zamajoni omzimba zihlasela isibindi) okanye umonakalo wesibindi obangelwa lunyango okanye sisifo. Ugqirha wakho unokukuxelela ukuba ungasebenzisi inaliti ye-peginterferon alfa-2b.
• xelela ugqirha wakho ukuba ukhe wasebenzisa iziyobisi zasesitalatweni okanye amayeza amayeza awasebenzisileyo kwaye ukuba unayo okanye wakha wanaso isifo sokuphinda ubenaso (ukonakalisa amehlo abangelwa sisifo seswekile okanye ezinye iimeko), isifo seswekile, okanye isifo sedlala.
• xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha ipeginterferon alfa-2b inaliti, tsalela ugqirha wakho.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Buza ugqirha wakho ukuba wenzeni ukuba uphoswa yidosi. Sukujoba idosi ephindwe kabini ukulungiselela eyilahlekileyo.

Inaliti ye-Peginterferon alfa-2b inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isiyezi
• urhudo
• isicaphucaphu
• ukugabha
• iingxaki ngencasa okanye ngevumba
• Ukuphelelwa ngumdla wokutya
• Ukuba ndindisholo, ukutshisa, okanye ukurhawuzelela iingalo, izandla, imilenze okanye iinyawo
• ukukhohlela
• irhashalala
• ukulahleka kweenwele

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukukhawuleza kwentliziyo okanye okungaqhelekanga
• iintlungu zesifuba
• ubunzima bokuphefumla
• mthubi ulusu okanye amehlo
• ukudumba kwesisu
• ubunzima bokugxila
• uziva ubanda okanye ushushu ngalo lonke ixesha
• ubunzima okanye ukulahleka
• ukwanda kokoma
• ukwanda komchamo
• ukuphefumla okunesiqhamo
• ukunciphisa okanye ukungaboni kakuhle

Inaliti ye-Peginterferon alfa-2b inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Gcina iingqayi ezingaxutywanga zamayeza kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina amayeza axutywe kwifriji kwaye usebenzise ngaphakathi kweeyure ezingama-24. Musa ukuvumela amayeza ukuba ngumkhenkce.

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• ukudinwa kakhulu
• intloko ebuhlungu
• iintlungu zemisipha
• umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
• ukugruzuka okanye ukopha okungaqhelekanga

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho.

Musa ukuvumela omnye umntu asebenzise amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• Isylatron^®