Inaliti yeRamucirumab

Umxholo

• Ngaphambi kokufumana inaliti ye-ramucirumab,
• Inaliti yeRamucirumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

Inaliti yeRamucirumab isetyenziswa yodwa kwaye indibene nelinye iyeza lonyango lokunyanga umhlaza wesisu okanye umhlaza okule ndawo apho isisu sihlangana khona nesisu (ityhubhu phakathi komqala nesisu) xa ezi meko zingaphucuki emva konyango namanye amayeza. I-Ramucirumab iphinda isetyenziswe ngokudibanisa ne-docetaxel ukunyanga uhlobo oluthile lomhlaza wesifo somhlaza ongasencinci (i-NSCLC) ethe yasasazeka kwamanye amalungu omzimba wabantu abasele bephethwe ngamanye amayeza e-chemotherapy kwaye abangakhange baphucule okanye babe mandundu. Ikwasetyenziswa ngokudibeneyo ne-erlotinib (Tarceva) kuhlobo oluthile lwe-NSCLC ethe yasasazeka kwamanye amalungu omzimba. I-Ramucirumab ikwasetyenziswa ngokudibeneyo namanye amayeza e-chemotherapy ukunyanga umhlaza wekholoni (amathumbu amakhulu) okanye i-rectum ethe yasasazeka kwamanye amalungu omzimba kubantu esele baphathwe ngamanye amayeza e-chemotherapy kwaye khange baphucule okanye babe mandundu. I-Ramucirumab ikwasetyenziselwa yodwa ukunyanga abantu abathile abane-hepatocellular carcinoma (HCC; uhlobo lomhlaza wesibindi) esele baphathwa nge-sorafenib (Nexafar). URamucirumab ukwiklasi yamayeza abizwa ngokuba ngamachiza omzimba. Isebenza ngokumisa ukukhula kweeseli zomhlaza.

Inaliti yeRamucirumab iza njengolwelo oluza kungeniswa emthanjeni ngaphezulu kwemizuzu engama-30 okanye engama-60 ngugqirha okanye ngumongikazi esibhedlele okanye kwiziko lonyango. Unyango lomhlaza wesisu, umhlaza wekholoni okanye i-rectum, okanye i-HCC, ihlala inikwa kube kanye kwiiveki ezi-2. Unyango lwe-NSCLC kunye ne-erlotinib, i-ramucirumab ihlala inikwa kube kanye kwiiveki ezi-2. Unyango lwe-NSCLC kunye ne-docetaxel, i-ramucirumab ihlala inikwa kube kanye kwiiveki ezi-3. Ubude bonyango lwakho buxhomekeke kwindlela ophendula ngayo emzimbeni wakho kunyango nakwiziphumo ebezingalindelekanga ohlangabezana nazo.

Ugqirha wakho unokufuna ukuphazamisa okanye ayeke unyango lwakho ukuba uneziphumo ebezingalindelekanga ezithile. Ugqirha wakho uya kukunika amanye amayeza okuthintela okanye ukunyanga iziphumo ebezingalindelekanga ezithile ngaphambi kokuba ufumane idosi nganye yenaliti ye-ramucirumab. Xelela ugqirha wakho okanye unesi ukuba uhlangabezana nenye yezi zinto zilandelayo ngelixa ufumana i-ramucirumab: ukushukuma okungalawulekiyo kwilungu lomzimba; intlungu emva okanye i-spasms; iintlungu zesifuba kunye nokuqina; Ukugodola; ukugungxula; ukuqhawukelwa ngumphefumlo; ukuvutha; iintlungu, ukutshisa, ukuba ndindisholo, ukuhlaba, okanye ukubetha ezandleni okanye ezinyaweni okanye kulusu; ubunzima bokuphefumla; okanye ukubetha kwentliziyo okukhawulezayo.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-ramucirumab,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-ramucirumab okanye nawaphi na amanye amayeza okanye ezinye izithako kwiinaliti ye-ramucirumab. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe wakha waba noxinzelelo lwegazi oluphezulu, okanye isifo sedlala lengqula okanye sesibindi. Xelela ugqirha wakho ukuba unenxeba elingekapholi okwangoku, okanye ukuba ukhula ngenxeba ngexesha lonyango olunganyangeki kakuhle.
• Kuya kufuneka uyazi ukuba i-ramucirumab inokubangela ukungachumi kwabasetyhini (kunzima ukukhulelwa); Nangona kunjalo, akufuneki ucinge ukuba awungekhe ukhulelwe. Tshela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Kufuneka ufumane uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango. Kuya kufuneka usebenzise ulawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kwaye ubuncinci iinyanga ezi-3 emva konyango lwakho lokugqibela. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngexesha lonyango lwakho ngenaliti ye-ramucirumab, tsalela ugqirha ngokukhawuleza. I-Ramucirumab inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa. Akufanele uncancise ngexesha lonyango lwakho kunye ne-ramucirumab kunye neenyanga ezi-2 emva kwedosi yakho yokugqibela.
• ukuba uyenziwa utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba ufumana inaliti ye-ramucirumab. Ugqirha wakho angakuxelela ukuba ungayifumani inaliti ye-ramucirumab ngeentsuku ezingama-28 ngaphambi kotyando lwakho. Unokuvunyelwa kuphela ukuqala kwakhona unyango ngenaliti ye-ramucirumab ukuba ubuncinci iintsuku ezili-14 emva kotyando lwakho kwaye inxeba laphola.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Biza ugqirha wakho ngoko nangoko ukuba awukwazi ukugcina ixesha lokuqeshwa ukuze ufumane idosi yenaliti ye-ramucirumab.

Inaliti yeRamucirumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• urhudo
• izilonda emlonyeni okanye emqaleni

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko:

• irhashalala
• ukuba buthathaka ngesiquphe kwengalo okanye umlenze
• ukujongwa kwelinye icala lobuso
• kunzima ukuthetha okanye ukuqonda
• ukutyumza isifuba okanye iintlungu zamagxa
• intetho ecothayo okanye enzima
• iintlungu zesifuba
• ukuqhawukelwa ngumphefumlo
• intloko ebuhlungu
• isiyezi okanye ukudinwa
• ukuxhuzula
• ukudideka
• utshintsho kumbono okanye ukulahleka kombono
• ukudinwa kakhulu
• ukudumba kobuso, amehlo, isisu, izandla, iinyawo, amaqatha okanye imilenze esezantsi
• ukuzuza ubunzima obungachazwanga
• umchamo wegwebu
• umqala obuhlungu, umkhuhlane, ukugodola, ukukhohlela okungapheliyo kunye nokudibana, okanye ezinye iimpawu zosulelo
• ukukhwehlela okanye ukugabha igazi okanye izinto ezibonakala ngathi ziindawo zekofu, ukopha okungaqhelekanga okanye ukugruzuka, pinki, bomvu, okanye umchamo omdaka mnyama, obomvu okanye ukulinda ukuhamba kwamathumbu amnyama,
• urhudo, ukugabha, iintlungu esiswini, umkhuhlane, okanye Ukugodola

Inaliti yeRamucirumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Kwezinye iimeko, ugqirha wakho unokuyalela uvavanyo lwelebhu ngaphambi kokuba uqale unyango lwakho ukuze ubone ukuba umhlaza wakho unganyangwa nge-ramucirumab. Ugqirha wakho uyakujonga uxinzelelo lwegazi kwaye avavanye umchamo wakho rhoqo ngexesha lonyango nge-ramucirumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• ICyramza^®