Inaliti yeAvelumab

Umxholo

• Ngaphambi kokufumana inaliti ye-avelumab,
• I-Avelumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo le-HOW, tsalela umnxeba kwangoko okanye ufumane unyango lonyango:

Inaliti ye-Avelumab isetyenziselwa ukunyanga iMerkel cell carcinoma (MCC; uhlobo lomhlaza wolusu) ethe yanwenwela kwamanye amalungu omzimba kubantu abadala nakubantwana abaneminyaka eli-12 ubudala nangaphezulu. Inaliti ye-Avelumab ikwasetyenziselwa ukunyanga umhlaza we-urothelial (umhlaza welinen yesinyi kunye nezinye iinxalenye zendlela yokuchama) ethe yasasazeka kwizicubu ezikufuphi okanye amanye amalungu omzimba wabantu abanomhlaza obubi ngexesha okanye ngaphakathi kweenyanga ezili-12 emva kokuba waphathwa ngamayeza eplatinum chemotherapy. Isetyenziswa njengonyango oluqhubekayo lomhlaza womchamo osasazeke kwizicwili ezikufutshane okanye kwamanye amalungu omzimba ukunceda ukugcina impendulo kwiplatinam chemotherapy. Inaliti ye-Avelumab ikwasetyenziswa ngokudibeneyo ne-axitinib (Inlyta) njengonyango lokuqala lwe-renal cell carcinoma (RCC; umhlaza oqala kwizintso) osasazekileyo okanye ongenakususwa ngotyando. Inaliti ye-Avelumab ikwiklasi yamayeza abizwa ngokuba ngamachiza omzimba. Isebenza ngokunceda umzimba ukuba ucothe okanye umise ukukhula kweeseli zomhlaza.

Inaliti ye-Avelumab iza njengesisombululo (ulwelo) ukujova ngaphakathi (emthanjeni) ngaphezulu kwemizuzu engama-60 ngugqirha okanye ngumongikazi kwiziko lonyango okanye kwiziko lokumnika. Ihlala inikwa kube kanye kwiiveki ezi-2. Ugqirha wakho uya kuthatha isigqibo sokuba uyifumana kangaphi i-avelumab esekwe ekuphenduleni komzimba wakho kweli yeza.

Inaliti ye-Avelumab inokubangela iimpendulo ezinzulu ngexesha lokufakwa kweyeza. Unokunikwa amanye amayeza ukunyanga okanye ukunceda ukuthintela ukusabela kwi-avelumab. Ugqirha okanye umongikazi uya kukujonga ngononophelo ngelixa ufumana amayeza. Xelela ugqirha wakho okanye umongikazi kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo ngexesha lokufakwa ngaphakathi: ukugodola okanye ukugungqa, isifuba, umkhuhlane, ukugungxula, iintlungu zomqolo, ukuphefumla kancinci, ukuvutha, okanye iintlungu esiswini. Ugqirha wakho unokufuna ukunciphisa ukunyuswa kwakho okanye ukulibaziseka okanye ukuyeka ngokusisigxina unyango lwakho xa ufumana ezi ziphumo zecala.

Ugqirha wakho unokuyeka isigxina unyango lwakho okanye akweze okwexeshana, okanye akuncede ngamanye amayeza xa unezinye iziphumo ebezingalindelekanga. Qiniseka ukuba uxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho ngenaliti ye-avelumab.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango ngenaliti ye-avelumab kwaye ngalo lonke ixesha ufumana iyeza. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana inaliti ye-avelumab,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-avelumab, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ye-avelumab. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe unesifo seswekile, isifo sikaCrohn (imeko apho umzimba uhlasela ulwelo lokugaya ukutya, ubangela iintlungu, urhudo, ukwehla kobunzima, kunye nefiva), ulcerative colitis (imeko ebangela ukudumba kunye izilonda kumngxunya wekholoni [amathumbu amakhulu] kunye ne-rectum), ukufakelwa komzimba, okanye isibindi, umphunga, okanye isifo sezintso.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Sebenzisa indlela ethembekileyo yolawulo lokuzalwa ukuthintela ukukhulelwa ngexesha lonyango lwakho kunye nenyanga e-1 emva kwedosi yakho yokugqibela ye-avelumab. Thetha nogqirha wakho malunga neendlela zokulawula ukuzalwa eziza kukusebenzela. Ukuba ukhulelwa ngelixa ufumana i-avelumab, biza ugqirha wakho ngokukhawuleza. I-Avelumab inokulimaza umbungu.
• xelela ugqirha wakho ukuba uncelisa okanye ucwangcisa ukuncancisa. Akufanele uncancise ngelixa ufumana i-avelumab kunye ne-1 inyanga emva kwethamo lakho lokugqibela.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphoswa idinga lokufumana i-avelumab, biza ugqirha wakho ngokukhawuleza.

I-Avelumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• izihlunu, ithambo, okanye iintlungu ezidibeneyo
• intloko ebuhlungu
• ukuqhina
• urhudo
• intlungu zesisu
• isicaphucaphu
• ukugabha
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• ukudinwa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo le-HOW, tsalela umnxeba kwangoko okanye ufumane unyango lonyango:

• ukukhwehlela okutsha okanye okuya kusiba mandundu; ukuqhawukelwa ngumphefumlo; okanye iintlungu esifubeni
• isicaphucaphu; ukugabha; iintlungu kwicala lasekunene lesisu; umchamo omnyama (onetayi); ukudinwa kakhulu; okanye ukugruzuka okungaqhelekanga okanye ukopha
• ukubetha kwentliziyo ngokukhawuleza; ukuqhina; ukwanda kokubila; Ukutshintsha kwelizwi; utshintsho lobunzima; ukuziva unxaniwe kunesiqhelo; isiyezi okanye ukuphelelwa ngamandla; ukulahleka kweenwele; isicaphucaphu; ukugabha; utshintsho kwiimvakalelo; isisu esibuhlungu; okanye ndiziva ndibanda
• iintlungu kwindawo ephezulu yesisu; ubumthubi besikhumba okanye amehlo; isicaphucaphu; ukugabha, okanye ukopha ngokulula okanye ukugruzuka
• urhudo; igazi kwizitulo; mnyama, linda, izitulo ezinamathelayo; okanye indawo esiswini iintlungu okanye ukuthamba
• ubuthathaka bemisipha
• ukozela
• uziva unesiyezi okanye ufe isiqaqa
• ukudumba kweenyawo kunye nemilenze
• iintlungu zesifuba kunye nokuxinana
• umkhuhlane okanye ezinye iimpawu ezinje ngomkhuhlane
• utshintsho lombono
• Intliziyo iyatshintsha
• irhashalala, ukudumba okanye ukuxobuka ulusu
• ubunzima bokuphefumla okanye ukugwinya
• ukuncipha kokuchama; igazi kumchamo; ukudumba emaqatheni; okanye ukuphelelwa ngumdla wokutya
• ukopha okungaqhelekanga okanye ukugruzuka
• Ukuchama rhoqo, okubuhlungu, okanye okungxamisekileyo

Inaliti ye-Avelumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa ufumana eliyeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho angayalela iimvavanyo ezithile zebhu ngaphambi nangexesha lonyango lwakho ukujonga impendulo yomzimba wakho kwi-avelumab.

Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nenaliti ye-avelumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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