Inaliti yeBelimumab

Umxholo

• Ngaphambi kokusebenzisa i-belimumab,
• I-Belimumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo le-INDLELA, tsalela ugqirha ngokukhawuleza:

I-Belimumab isetyenziselwa namanye amayeza ukunyanga iintlobo ezithile ze-systemic lupus erythematosus (SLE okanye lupus; isifo esizenzekelayo apho amajoni omzimba ahlasela amalungu asempilweni omzimba njengamalungu, ulusu, imithambo yegazi, kunye nezitho) kubantu abadala nakubantwana iminyaka yobudala nangaphezulu. I-Belimumab ikwasetyenziswa kunye namanye amayeza ukunyanga i-lupus nephritis (isifo somzimba apho amajoni omzimba ahlasela izintso) kubantu abadala. I-Belimumab ikwiklasi yamayeza abizwa ngokuba yi-monoclonal antibodies. Isebenza ngokuthintela umsebenzi weprotein ethile kubantu abane-SLE kunye ne-lupus nephritis.

I-Belimumab iza njengomgubo oza kuxutywa kwisisombululo sokujova ngaphakathi (emthanjeni) kubantu abadala nakubantwana abaneminyaka emi-5 ubudala nangaphezulu. I-Belimumab iza nesisombululo (ulwelo) kwi-autoinjector okanye isirinji ekhethiweyo yokujova (ngaphantsi kolusu) kubantu abadala. Xa unikezwe ngaphakathi ngaphakathi, ihlala inikwa ubuncinci iyure ngugqirha okanye ngumongikazi kube kanye kwiiveki ezimbini kwiidosi zokuqala ezintathu, kwaye kube kanye kwiiveki ezi-4. Ugqirha wakho uya kuthatha isigqibo sokuba uyifumana kangaphi i-belimumab efakwe ngaphakathi ngaphakathi ngokuxhomekeke ekuphenduleni komzimba wakho kweli yeza. Xa unikwe ngendlela engaphantsi, ihlala inikwa kanye ngeveki ngokukhethekileyo kwangolo suku lunye evekini.

Uya kufumana idosi yakho yokuqala engaphantsi kwe-belimumab inaliti kwiofisi kagqirha wakho. Ukuba uza kutofa inaliti ye-belimumab ngokwakho ekhaya okanye unetshomi okanye isihlobo sikufakele iyeza, ugqirha wakho uya kukubonisa okanye umntu oza kungenza iyeza ukuba ungalitofa njani. Wena kunye nomntu oza kutofa iyeza kufuneka ufunde imiyalelo ebhaliweyo yokusetyenziswa okuza nonyango.

Susa i-autoinjector okanye isirinji ekhethiweyo efrijini kwaye uyivumele ukuba ifikelele kubushushu begumbi kwimizuzu engama-30 ngaphambi kokuba ulungele ukutofa inaliti ye-belimumab. Sukuzama ukufudumeza amayeza ngokuwatshisa kwimicrowave, ngokuwabeka emanzini afudumeleyo, okanye ngayo nayiphi na enye indlela. Isisombululo kufuneka sicace kwi-opalescent kwaye singenambala ukuya kumbala otyheli. Fowunela usokhemesti wakho ukuba kukho naziphi na iingxaki kwiphakheji okanye isirinji kwaye ungalitofisi iyeza.

Unokufaka inaliti ye-belimumab ngaphambili kwamathanga okanye naphina esiswini sakho ngaphandle kwenkaba yakho (iqhosha lesisu) kunye nendawo eyi-intshi ezi-2 ezijikeleze yona. Musa ukujova iyeza kulusu olunethenda, elityumkileyo, elibomvu, elilukhuni, okanye elingaphelelanga. Khetha indawo eyahlukileyo ngalo lonke ixesha utofa iyeza.

I-Belimumab inokubangela iimpendulo ezinzulu ngexesha nasemva kokufumana amayeza. Ugqirha okanye umongikazi uya kukujonga ngokusondeleyo ngelixa ufumana ukumiliselwa kunye nasemva kokufakwa ukuze uqiniseke ukuba awunampendulo imbi kunyango. Unokunikwa amanye amayeza ukunyanga okanye ukunceda ukuthintela ukusabela kwi-belimumab. Xelela ugqirha wakho okanye umongikazi kwangoko ukuba unazo naziphi na kwezi mpawu zilandelayo ezinokuthi zenzeke ngexesha lokufakwa ngaphakathi okanye ngenaliti yesikhumba okanye kwisithuba seveki emva kokuba ufumene iyeza: ukurhawuzelela; imihlathi ukudumba kobuso, amehlo, umlomo, umqala, ulwimi, okanye imilebe; ubunzima bokuphefumla okanye ukugwinya; ukuvutha okanye ukuphefumla okufutshane; ixhala; ukugungxula; isiyezi; isiqaqa; intloko ebuhlungu; isicaphucaphu; ifiva; Ukugodola; ukuxhuzula; iintlungu zemisipha; kunye nokubetha kwentliziyo kancinci.

I-Belimumab inceda ukulawula i-lupus kodwa ayiyinyangi. Ugqirha wakho uyakukujonga ngononophelo ukuze ubone ukuba isebenza njani i-belimumab. Kungathatha ixesha ngaphambi kokuba uzive uzuze ngokupheleleyo nge-belimumab. Kubalulekile ukuxelela ugqirha wakho ukuba uziva njani ngexesha lonyango lwakho.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-belimumab kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya kunye noLawulo lweziyobisi (FDA) http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm okanye iwebhusayithi yomenzi ukufumana isiKhokelo seMithi.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokusebenzisa i-belimumab,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-belimumab, nawaphi na amanye amayeza, okanye naziphi na izithako kwiinaliti ze-belimumab. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: cyclophosphamide efakwa emithanjeni; kunye nee-antibodies ze-monoclonal okanye amanye amayeza e-biologic. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unentsholongwane okanye ukuba unayo okanye ukhe wosuleleka uqhubeka ubuya, uxinzelelo okanye iingcinga zokuzenzakalisa okanye ukuzibulala, okanye umhlaza.
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ayaziwa ukuba ukuthatha i-belimumab ngexesha lokukhulelwa kunokulimaza umntwana wakho ongakazalwa. Ukuba ukhetha ukuthintela ukukhulelwa, kuya kufuneka usebenzise ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye ne-belimumab kunye neenyanga ezi-4 emva kwedosi yakho yokugqibela. Thetha nogqirha wakho ngeendlela zolawulo lokuzalwa onokuzisebenzisa ngexesha lonyango lwakho. Ukuba ukhulelwa ngexesha lonyango lwakho nge-belimumab, tsalela ugqirha wakho.
• xelela ugqirha wakho ukuba uncelisa.
• ukuba wenza utyando, kubandakanya utyando lwamazinyo, xelela ugqirha okanye ugqirha wamazinyo ukuba usebenzisa i-belimumab.
• awunalo ugonyo ngaphandle kokuthetha nogqirha wakho. Tshela ugqirha wakho ukuba ufumene isitofu sokugonya kwiintsuku ezingama-30 ezidlulileyo.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.

Ukuba uphosa ixesha lokufumana i-belimumab infusion, tsalela ugqirha ngokukhawuleza.

Ukuba uyaphoswa yidosi engaphantsi yesitofu se-belimumab, jola idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Emva koko, jofa idosi yakho elandelayo ngexesha lakho elimiselweyo okanye uqhubeke nedosi yeveki nganye ngokusekwe kumhla omtsha wokutofa. Sukujoba idosi ephindwe kabini ukulungiselela eyilahlekileyo. Biza ugqirha wakho okanye usokhemesti ukuba ufuna uncedo lokuthatha isigqibo sokuba uza kutofa nini inaliti ye-belimumab.

I-Belimumab inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• urhudo
• intloko ebuhlungu okanye migraine
• ubunzima bokulala okanye ukulala
• ububomvu, ukurhawuzelela, ukudumba, iintlungu, ukujika kombala, okanye ukucaphuka kwindawo yenaliti
• iintlungu ezingalweni okanye emilenzeni
• impumlo enemifinya

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo le-INDLELA, tsalela ugqirha ngokukhawuleza:

• irhashalala
• urhwebo
• ukurhawuzelela
• ukuqhawukelwa ngumphefumlo
• ukudumba kobuso, umqala, ulwimi, imilebe namehlo
• ubunzima bokuphefumla okanye ukugwinya
• umkhuhlane, umqala obuhlungu, Ukugodola, ukukhohlela, kunye neminye imiqondiso yosulelo
• kushushu; bomvu, okanye isikhumba esibuhlungu okanye izilonda emzimbeni wakho
• ucinga ngokwenzakalisa okanye ukuzibulala okanye ubulale abanye, okanye ucwangcise okanye uzame ukwenza njalo
• ukudakumba okutsha okanye okubaxekileyo
• utshintsho olungaqhelekanga kwindlela oziphatha ngayo okanye kwimeko yakho
• ukwenza izinto eziyingozi
• Ukuchama rhoqo, okubuhlungu, okanye kunzima
• kunamafu okanye umchamo onamandla onukayo
• ukukhohlela umchamo
• utshintsho lombono
• ukulahleka kwememori
• ubunzima bokucinga ngokucacileyo
• kunzima ukuthetha okanye ukuhamba
• isiyezi okanye ukulahleka kwemali eseleyo

I-Belimumab inokunyusa umngcipheko wee-cancer ezithile. Izifundo zibonise ukuba abantu abafumene i-belimumab babesengozini yokufa kwizizathu ezahlukeneyo kunabo bangakhange bathathe i-belimumab. Thetha nogqirha wakho malunga neengozi zokufumana eli yeza.

I-Belimumab inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unayo nayiphi na ingxaki engaqhelekanga ngelixa usebenzisa eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina la mayeza kwiphakeji engenileyo, kude nokukhanya, ivaliwe ngokuqinileyo, kwaye ayifumaneki ebantwaneni. Musa ukushukumisa ii-autoinjectors okanye iisirinji ezikhethiweyo eziqulethe i-belimumab. Gcina inaliti ye-belimumab kwifriji; sukuma ngumkhenkce. Gwema ukutyhila ubushushu. Iisirinji zinokugcinwa ngaphandle kwefriji (ukuya kuthi ga kwi-30 ° C) ukuya kuthi ga kwiiyure ezili-12 ukuba zikhuselwe elangeni. Sukusebenzisa iisirinji kwaye ungazibeki kwifriji ukuba azifakwanga efrijini ngaphezulu kweeyure ezili-12. Lahla naliphi na iyeza eliphelelwe lixesha okanye elingasafunekiyo. Thetha kumachiza wakho malunga nokulahla ngokufanelekileyo amayeza akho.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Buza i-pharmist yakho nayiphi na imibuzo onayo malunga nenaliti ye-belimumab.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

• UBenlysta^®