Safinamide

Umxholo

• Ngaphambi kokuba uthathe i-safinamide,
• I-Safinamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

ISafinamide isetyenziswa kunye nendibaniselwano ye-levodopa kunye ne-carbidopa (iDuopa, iRytary, iSinemet, nezinye) ukunyanga iziqendu '' zokucima '' (amaxesha obunzima bokuhamba, ukuhamba, nokuthetha okungenzeka xa amayeza ephela okanye engahlelanga) abantu abanesifo sikaParkinson's (PD; ukuphazamiseka kwenkqubo yemithambo-luvo ebangela ubunzima ngokuhamba, ukulawula izihlunu, kunye nokulingana). I-Safinamide ikwiqela lamayeza abizwa ngokuba yi-monoamine oxidase type B (MAO-B) inhibitors. Isebenza ngokwandisa inani le-dopamine (into yendalo efunekayo ukulawula ukuhamba) kwingqondo.

ISafinamide iza njengecwecwe lokuthatha ngomlomo. Ihlala ithathwa kunye okanye ngaphandle kokutya kube kanye yonke imihla. Thatha i-safinamide malunga nexesha elifanayo yonke imihla. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-safinamide ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ugqirha wakho uya kukuqala ngedosi esezantsi ye-safinamide kwaye unokunyusa idosi yakho kube kanye emva kweeveki ezi-2 zonyango.

Sukuyeka ukuthatha i-safinamide ngaphandle kokuthetha nogqirha wakho. Ugqirha wakho uya kunciphisa umthamo wakho ngaphambi kokuyeka. Ukuba ngequbuliso uyeka ukuthatha i-safinamide, unokufumana iimpawu zokurhoxa ezifana nomkhuhlane; ukuqina kwemisipha; ukudideka; okanye utshintsho olwazini. Xelela ugqirha wakho ukuba unazo naziphi na kwezi mpawu xa idosi yakho ye-safinamide inciphile.

Buza usokhemesti okanye ugqirha wakho ngekopi yolwazi lomenzi wesigulana.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokuba uthathe i-safinamide,

• xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uyaliwa yi-safinamide (ukudumba umlomo okanye ulwimi, ukuphefumla kancinci), nawaphi na amanye amayeza, okanye naziphi na izithako ezikwiipilisi ze-safinamide. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho ukuba ngaba uthatha enye yezi zinto zilandelayo: amphetamines (izinto ezikhuthazayo, ’uppers’) ezifana neamphetamine (Adderall, Adzenys, Dyanavel XR, eAdderall), dextroamphetamine (Dexedrine, eAdderall), kunye methamphetamine (Desoxyn); iziyobisi ezithile ezifana ne-amitriptyline (Elavil), amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), mirtazapine (Remeron) kunye ne-trazodone; buspirone; cyclobenzaprine (Amrix); methylphenidate (Aptensio, Metadate, Ritalin, nabanye); iiopioid ezinje nge-meperidine (Demerol), methadone (iDolophine, iMethadose), ipropoxyphene (ayisafumaneki e-US; iDarvon), okanye i-tramadol (iConzip, i-Ultram, kwi-Ultracet); i-serotonin ekhethiweyo kunye ne-norepinephrine reuptake inhibitors (i-SSNRIs) enjenge-duloxetine (iCymbalta) kunye ne-venlafaxine (i-Effexor); kunye neSt. Xelela ugqirha wakho ukuba uthatha i-MAO inhibitor efana ne-isocarboxazid (Marplan), linezolid (Zyvox), methylene luhlaza, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), okanye tranylcypromine (Parnate) okanye uyekile ukuthatha kwiiveki ezimbini ezidlulileyo. Ugqirha wakho uya kukuxelela ukuba akufuneki uthathe i-safinamide kunye nalawaphi na amayeza. Ukuba uyeka ukuthatha i-safinamide, kuya kufuneka ulinde ubuncinci iintsuku ezili-14 ngaphambi kokuba uqale ukuthatha naliphi na kula mayeza. Kwakhona, sukuthatha i-dextromethorphan (kwiRobitussin DM; ifunyenwe kwisikhohlela esingabhaliswanga kunye neemveliso ezibandayo) kunye ne-safinamide.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: i-antipsychotic efana ne-clozapine (Clozaril, Fazaclo, Versacloz) kunye ne-olanzapine (Zyprexa); i-benzodiazepines ezinje nge-alprazolam (Xanax), diazepam (Diastat, Valium), lorazepam (Ativan), temazepam (Restoril), kunye netriazolam (Halcion); amayeza emikhuhlane kunye ne-allergies (i-decongestants) kubandakanya nezo zibekwe kwiliso okanye empumlweni; imatinib (Gleevec); irinotecan (Camptosar, Onivyde); isoniazid (Laniazid, eRifamate, eRifater); lapatinib (iTykerb); imethotrexate (Otrexup, Rasuvo); metoclopramide (Reglan); mitoxantrone; irosuvastatin (Crestor); i-serotonin reuptake inhibitors ekhethiweyo njenge citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax, abanye), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), kunye sertraline (Zoloft); isulfasalazine (Azulfidine); kunye ne-topotecan (Hycamtin). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba unesifo sesibindi. Ugqirha wakho uya kukuxelela ukuba ungathathi i-safinamide.
• xelela ugqirha wakho ukuba ukhe okanye wakha wagula ngengqondo njenge-schizophrenia (isifo sengqondo esibangela ukuphazamiseka ekucingeni, ukuphelelwa ngumdla ebomini, kunye neemvakalelo ezinamandla okanye ezingaqhelekanga), ukuphazamiseka kwengqondo okuguquguqukayo (imeko etshintsha ukusuka kuxinzelelo ukuya kwimincili engaqhelekanga) , okanye isifo sengqondo; okanye ukuba unoxinzelelo lwegazi oluphezulu okanye oluphantsi; idyskinesia (iintshukumo ezingaqhelekanga); okanye iingxaki zokulala. Xelela ugqirha wakho ukuba wena okanye ilungu losapho unengxaki okanye une-retina yamehlo okanye i-albinism (imeko efunyanwa njengelifa ebangela ukungabikho kombala kulusu, iinwele namehlo).
• xelela ugqirha wakho ukuba ukhulelwe okanye ucwangcise ukukhulelwa. Ukuba ukhulelwa ngelixa uthatha i-safinamide, tsalela ugqirha wakho.
• xelela ugqirha wakho ukuba uncancisa okanye ucwangcise ukuncancisa.
• Kuya kufuneka uyazi ukuba i-safinamide inokukwenza wozele okanye inokubangela ukuba ulale ngesiquphe ngexesha lomsebenzi wakho wemihla ngemihla. Usenokuziva ukozela okanye ungabinayo nayiphi na imiqondiso ngaphambi kokuba ulale ngequbuliso.Musa ukuqhuba imoto, ukusebenzisa oomatshini, ukusebenza kwiindawo eziphakamileyo, okanye ukuthatha inxaxheba kwizinto ezinokuba yingozi ekuqaleni konyango lwakho de ube uyazi ukuba lichaphazela njani iyeza. Ukuba ngequbuliso ulale xa usenza into enjengokubukela umabonwakude, ukuthetha, ukutya, okanye ukukhwela emotweni, okanye ukuba uyozela kakhulu, ngakumbi ngexesha lasemini, tsalela umnxeba ugqirha wakho. Musa ukuqhuba, ukusebenza kwiindawo eziphakamileyo, okanye ukusebenzisa oomatshini de uthethe nogqirha wakho.
• khumbula ukuba utywala bunokongeza ukozela okubangelwa leli yeza. Musa ukusela utywala ngelixa uthatha i-safinamide.
• Kuya kufuneka uyazi ukuba abanye abantu abathathe amayeza afana ne-safinamide bahlakulela iingxaki zokungcakaza okanye ezinye iindlela ezinamandla zokuziphatha okanye zokuziphatha ezinyanzelekileyo okanye ezingaqhelekanga kubo, njengokunyusa iminqweno yesini okanye isimilo. Tsalela umnxeba ugqirha wakho ukuba unomdla wokungcakaza ekunzima ukuwulawula, uneminqweno enzulu, okanye awukwazi ukulawula indlela oziphethe ngayo. Xelela amalungu osapho lwakho ngalo mngcipheko ukuze bakwazi ukubiza ugqirha nokuba awuqondi ukuba ukungcakaza kwakho okanye nayiphi na eminye iminqweno enzulu okanye indlela yokuziphatha engaqhelekanga ibe yingxaki.

Unokufumana impendulo enzulu ukuba utya ukutya okuphezulu kwi-tyramine ngexesha lonyango lwakho nge-safinamide. I-Tyramine ifumaneka kukutya nakwiziselo ezininzi, kubandakanya inyama, iinkukhu, intlanzi, okanye itshizi etshayiweyo, endala, egcinwe ngokungafanelekanga, okanye eyonakeleyo; iziqhamo ezithile, imifuno, neembotyi; iziselo ezinxilisayo; kunye nemveliso yegwele enegwele. Ugqirha wakho okanye ugqirha otya ukutya okutyayo uya kukuxelela ukuba kukuphi ukutya ekufuneka ukuphephe ngokupheleleyo, kunye nokutya onokukutya ngexabiso elincinci. Ukuba utya ukutya okuphezulu kwi-tyramine ngelixa uthatha i-safinamide, nxibelelana nogqirha wakho.

Tsiba idosi ephosiweyo kwaye uthathe idosi yakho elandelayo ngexesha eliqhelekileyo ngosuku olulandelayo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Safinamide inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ubunzima bokulala okanye ukulala

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba unazo naziphi na kwezi mpawu, biza ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

• ukwanda okanye ukuhamba rhoqo komzimba ongenakukulawula
• utshintsho lombono
• ukubona izinto ezingekhoyo (ukubona izinto okanye ukuva amazwi angabikho)
• iinkolelo ezingekhoyo (ukukholelwa izinto ezingezizo)
• Ukuphazamiseka, ukubona izinto ezingekhoyo, umkhuhlane, ukubila, ukudideka, ukubetha kwentliziyo okukhawulezayo, ukungcangcazela, ukuqina kwemisipha okanye ukujijeka, ukulahleka kokulungelelaniswa, isicaphucaphu, ukugabha, okanye urhudo

I-Safinamide inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela).

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Gcina lonke ixesha lokudibana nogqirha wakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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