Amaxabiso okusinda kunye ne-Outlook ye-Acute Lymphocytic Leukemia (BONKE)

Umxholo

• Athini amazinga okusinda BONKE?
• Ebantwaneni
• Zeziphi izinto ezichaphazela inqanaba lokusinda?
• Ubudala bunasiphi isiphumo kwinqanaba lokusinda?
• Luluphi ifuthe LONKE uhlobo olunenqanaba lokusinda?
• Ukuchaphazeleka kweChromosomal
• Impembelelo yempatho yonyango inaliphi inqanaba lokusinda?
• Ukusasazeka KONKE kunaliphi ifuthe kwinqanaba lokusinda?
• Lithini ifuthe lokubala kweWBC kwizinga lokusinda?
• Umntu angamelana njani nokufuna inkxaso?
• Phanda ngesi sifo
• Fikelela kwiqela lakho lokhathalelo lwempilo
• Cinga ngonyango olongezelelekileyo
• Yenza indawo yokwabelana kubahlobo kunye nabantu obathandayo

Yintoni i-acute lymphocytic leukemia (BONKE)?

I-leukemia ye-lymphocytic Acute (YONKE) luhlobo lomhlaza. Inxalenye nganye yegama layo ikuxelela into malunga nomhlaza ngokwawo:

• Ngamandla. Umhlaza uhlala ukhula ngokukhawuleza kwaye ufuna ukufunyanwa kwangoko kunye nonyango. Ngaphandle konyango, iiseli zomongo wethambo azikwazi ukukhula ngokufanelekileyo, kwaye umntu akazukuba nomzimba owoneleyo, ovuthiweyo wethambo. Umongo wethambo uthatyathelwa indawo zii-lymphocyte ezikhula ngokukhawuleza ezingaqhelekanga.
• I-lymphocytic. Umhlaza uchaphazela ii-lymphocyte zeeseli ezimhlophe zegazi lomntu (ii-WBCs). Elinye igama elinokusetyenziswa yi-lymphoblastic.
• Ileukemia. Ileukemia ngumhlaza weeseli zegazi.

Iindidi ezininzi ZONKE zikhona. Amaxabiso okusinda BONKE axhomekeke kuhlobo lomntu onalo.

WONKE owona mhlaza uxhaphakileyo kubantwana, kodwa unamazinga aphezulu onyango ebantwaneni. Nangona amazinga okusinda engekho phezulu xa ekhula kubantu abadala, baya bephucula ngokuthe ngcembe.

Athini amazinga okusinda BONKE?

I-National Cancer Institute (NCI) iqikelela ukuba ngabantu abayi-5,960 abazakufumana ukuxilongwa KWABO BONKE e-United States ngo-2018. Malunga nabantu abayi-1,470 abazakusweleka kwesi sifo ngo-2018.

Izinto ezininzi zinokumisela amanqanaba okusinda, njengobudala ekufumanekeni kokuxilongwa kunye nohlobo lwazo ZONKE.

Inqanaba lokusinda kweminyaka emihlanu e-United States ngama-68.1 epesenti, inika ingxelo i-NCI. Nangona kunjalo, la manani ayanda ngokuthe chu. Ukususela ngo-1975 ukuya ku-1976, iminyaka emihlanu yokuphila kuyo yonke iminyaka yayingaphantsi kwama-40 ekhulwini.

Nangona uninzi lwabantu lufumana ukuxilongwa KWABO BONKE ngabantwana, ipesenti ephezulu yabantu baseMelika abanabo BONKE abadlulayo baphakathi kweminyaka engama-65 nama-74.

Ngokubanzi, malunga neepesenti ezingama-40 zabantu abadala abaneZONKE zithathwa njengezinyangiwe ngexesha lokunyanga kwabo, uqikelelo I-American Cancer Society. Nangona kunjalo, la maxabiso onyango axhomekeke kwizinto ezahlukeneyo, ezinje nge-subtype yazo ZONKE kunye nobudala ekufumaniseni isifo.

Umntu "uphilisiwe" BONKE ukuba uxolelo olupheleleyo okanye ngaphezulu. Kodwa kuba kukho ithuba lokuba umhlaza ubuye, oogqirha abanakutsho ngepesenti eyi-100 yokuba umntu uyaphiliswa. Eyona nto banokuthi yiyo okanye akukho zimpawu zomhlaza ngelo xesha.

Ebantwaneni

Ngokwe-NCI, inqanaba lokusinda kweminyaka emihlanu kubantwana baseMelika abanazo ZONKE. Oku kuthetha ukuba iipesenti ezingama-85 zabantu baseMelika abanobuntwana BONKE baphila ubuncinci kwiminyaka emihlanu emva kokuba befumene isifo somhlaza.

Amaxabiso okusinda kubo BONKE, ngakumbi abantwana, aqhubeke nokuphucula ngokuhamba kwexesha njengoko kunyangwa unyango olutsha.

Oogqirha banokujonga uninzi lwaba bantwana ukuba lunyangeke kumhlaza wabo ukuba bebekhe baxola ngokupheleleyo ngaphezulu kweminyaka emihlanu. Ukuxolelwa kuthetha ukuba kuncitshisiwe imiqondiso kunye neempawu zomhlaza.

Ukuxolelwa kunokuba yinxalenye okanye kugqitywe. Ekuxolelweni ngokupheleleyo, awunazo iimpawu zomhlaza. BONKE banokubuyela emva kokuxolelwa, kodwa unyango lunokuqala kwakhona.

I-NCI ithi phakathi kwabantwana baseMelika BONKE, uqikelelo lufezekisa uxolelo. Ukuxolelwa kuthetha ukuba umntwana akanazo iimpawu okanye iimpawu zale meko kwaye ukubalwa kweeseli zegazi kungaphakathi kwemida eqhelekileyo.

Zeziphi izinto ezichaphazela inqanaba lokusinda?

Zininzi izinto ezinokuchaphazela inqanaba lokusinda komntu kulandela ukuxilongwa KONKE, okufana nobudala bomntu okanye ubalo lwe-WBC ngexesha lokuxilongwa. Oogqirha bajonga nganye yezi zinto xa benika umbono womntu.

Nangona kunjalo, kubalulekile ukuba ukhumbule ukuba le meko luqikelelo lukagqirha lokusinda kunikwa ulwazi lokuqonda abanalo ngoku.

Ubudala bunasiphi isiphumo kwinqanaba lokusinda?

Ngokutsho kwe-NCI, ezinye izifundo zifumene ukuba abantu banethuba elingcono lokusinda ukuba baneminyaka engama-35 ubudala okanye ngaphantsi. Ngokubanzi, abantu abadala abadala BONKE baya kuhlala benembono ehlwempuzekileyo kunabantu abancinci.

Abantwana bathathwa njengomngcipheko ophezulu ukuba bangaphezulu kweminyaka eli-10.

Luluphi ifuthe LONKE uhlobo olunenqanaba lokusinda?

Abantu abaneeseli ezincinci, kubandakanya i-pre-B, eqhelekileyo, okanye i-pre-B yangaphambi kwexesha, ngokubanzi bathathelwa ingqalelo njengamathuba okusinda angcono kunalawo ane-B-cell (Burkitt) leukemia evuthiweyo.

Ukuchaphazeleka kweChromosomal

Zininzi iintlobo ezahlukeneyo ZONKE ezikhoyo. Iicancer ezibangela ZONKE zingenza utshintsho olwahlukileyo kwii-chromosomes zomntu. Ugqirha obizwa ngokuba sisifo sengqondo uza kuvavanya iiseli ezinomhlaza phantsi kwemicroscope.

Iindidi ezininzi ezahlukeneyo zokuchaphazeleka kwe-chromosomal zinxulunyaniswa nembonakalo yobuhlwempu. Oku kubandakanya:

• I-Ph1-positive t (9; 22) engaqhelekanga
• I-BCR / ABL-i-leukemia ehlelwe ngokutsha
• t (4; 11)
• Ukucinywa kwe-chromosome 7
• iTrisomy 8

Ukuba ugqirha wakho wenza ukuxilongwa KONKE, baya kukuxelela ukuba uluphi uhlobo lweeseli ze-leukemia onayo.

Impembelelo yempatho yonyango inaliphi inqanaba lokusinda?

Abantu abaphendula ngokukhawuleza kunyango lwabo BONKE banokuba nembono engcono.Xa kuthatha ixesha elide ukufikelela kuxolelo, imbonakalo ihlala ingalunganga.

Ukuba unyango lomntu luthatha ixesha elingaphezulu kweeveki ezine ukuya kuxolelo, oku kunokuchaphazela umbono wabo.

Ukusasazeka KONKE kunaliphi ifuthe kwinqanaba lokusinda?

BONKE banokusasazeka kwi-cerebral spinal fluid (CSF) emzimbeni. Okukhulu ukusasazeka kwamalungu akufuphi, kubandakanya i-CSF, ihlwempu kukujonga.

Lithini ifuthe lokubala kweWBC kwizinga lokusinda?

Abo banenani eliphezulu kakhulu le-WBC ekufumaneni isifo (ihlala iphakeme kunama-50,000 ukuya kwi-100,000) banembono ehlwempuzekileyo.

Umntu angamelana njani nokufuna inkxaso?

Ukuva ugqirha ekuxelela ukuba unomhlaza akusokuze kube lula. Nangona kunjalo, iintlobo ezininzi ZONKE ziyanyangeka kakhulu. Ngelixa usenza unyango, zininzi iindlela zenkxaso ezikhoyo zokukunceda kolu hambo.

Ezinye zeendlela onokuzisebenzisa zidweliswe apha ngezantsi:

Phanda ngesi sifo

Ukufunda ngakumbi kwimibutho ehlonitshwayo, ephandwe kakuhle inokukunceda ukuba ube nolwazi malunga nemeko kunye nokhathalelo lwakho.

Imizekelo yezixhobo ezifanelekileyo zibandakanya:

• Umhlaza wegazi kunye neLymphoma Society
• Umbutho woMhlaza waseMelika

Fikelela kwiqela lakho lokhathalelo lwempilo

Unyango lomhlaza luhlala lubandakanya indlela yeqela kukhathalelo lwakho. Uninzi lwezixhobo zomhlaza zinabaqhubi benomhlaza abanokukufaka kunxibelelwano nezixhobo kunye nenkxaso.

Uninzi lweengcali zempilo zinokuxhasa wena okanye umntu omthandayo. Ziquka:

• oogqirha bengqondo
• oonontlalontle
• iingcali zokutya
• iingcali zobomi bomntwana
• abaphathi bamatyala
• Abefundisi

Cinga ngonyango olongezelelekileyo

Unyango olukhuthaza ukuphumla kunye noxinzelelo kunako ukuxhasa unyango lwakho. Imizekelo inokubandakanya ukuphululwa okanye ukulungiswa komzimba.

Soloko uthetha nogqirha wakho ngaphambi kokuqala naluphi na unyango olongezelelekileyo njengamayeza, iivithamini, okanye ukutya okhethekileyo.

Yenza indawo yokwabelana kubahlobo kunye nabantu obathandayo

Uya kudibana nabantu abaninzi abangathanda ukunceda okanye ukufumana uhlaziyo ngendlela oqhuba ngayo kunyango lwakho lonke.

Ukuba uvulelekile ekwabelaneni ngolu hlaziyo, jonga iphepha lewebhu elinje ngeCaring Bridge. Kubahlobo abafuna ukunceda, kukho izixhobo ezinje ngeSidlo soTya. Ivumela abahlobo ukuba babhalisele ukuhanjiswa kwesidlo.

Kubalulekile ukuba ukhumbule ukuba zininzi izihlobo, amalungu osapho, kunye nemibutho enqwenela ukukunceda kunyango lwakho kunye nokuchacha kubo BONKE.