Uvavanyo lwe-ALT (Alanine Aminotransferase)

Umxholo

• Yintoni uvavanyo lwe-ALT?
• Kutheni kwenziwa uvavanyo lwe-ALT?
• Ndilungiselela njani uvavanyo lwe-ALT?
• Uvavanyo lwe-ALT lwenziwa njani?
• Zithini iingozi ezinxulumene novavanyo lwe-ALT?
• Zithetha ntoni iziphumo zam zovavanyo lwe-ALT?
• Iziphumo eziqhelekileyo
• Iziphumo ezingaqhelekanga

Yintoni uvavanyo lwe-ALT?

Uvavanyo lwe-alanine aminotransferase (ALT) lwenqanaba le-ALT egazini lakho. I-ALT yi-enzyme eyenziwe ziiseli kwisibindi sakho.

Isibindi lelona dlala likhulu lomzimba. Inemisebenzi emininzi ebalulekileyo, kubandakanya:

• Ukwenza iiproteni
• ukugcina iivithamini kunye nentsimbi
• ususa ityhefu egazini lakho
• ukuvelisa i-bile, encedisa ekwetyisweni

Iiproteni ezibizwa ngokuba zii-enzymes zinceda ukuba isibindi sidilize ezinye iiprotein ukuze umzimba wakho uzifunxe ngokulula. I-ALT yenye yezi enzymes. Idlala indima ebalulekileyo kwimetabolism, inkqubo ejika ukutya kube ngamandla.

I-ALT ihlala ifumaneka ngaphakathi kweeseli zesibindi. Nangona kunjalo, xa isibindi sakho sonakalisiwe okanye sitshisiwe, i-ALT inokukhutshwa kwigazi lakho. Oku kubangela ukuba amanqanaba e-serum ALT anyuke.

Ukulinganisa inqanaba le-ALT egazini lomntu kunokunceda oogqirha bavavanye ukusebenza kwesibindi okanye babone oyena nobangela wengxaki yesibindi. Uvavanyo lwe-ALT luhlala luyinxalenye yovavanyo lokuqala lwezifo zesibindi.

Uvavanyo lwe-ALT lukwabizwa ngokuba luvavanyo lwe-serum glutamic-pyruvic transaminase (SGPT) okanye uvavanyo lwe-alanine transaminase.

Kutheni kwenziwa uvavanyo lwe-ALT?

Uvavanyo lwe-ALT luhlala lusetyenziselwa ukumisela ukuba umntu othile wenzakele esibindini okanye usilele. Ugqirha wakho unokuyalela uvavanyo lwe-ALT ukuba uneempawu zesifo sesibindi, kubandakanya:

• i-jaundice, etyheli ngamehlo akho okanye ulusu
• umchamo omnyama
• isicaphucaphu
• ukugabha
• iintlungu kwi-quadrant ephezulu yesisu sakho

Umonakalo wesibindi ngokubanzi ubangela ukwanda kwamanqanaba e-ALT. Uvavanyo lwe-ALT lunokuvavanya amanqanaba e-ALT kwigazi lakho, kodwa alinakubonisa ukuba ungakanani umonakalo wesibindi okhoyo okanye ingakanani i-fibrosis, okanye inkohliso, ekhoyo. Uvavanyo alunakuqikelela ukuba umonakalo wesibindi uza kuba nzima kangakanani.

Uvavanyo lwe-ALT luhlala lwenziwa nezinye iimvavanyo ze-enzyme yesibindi. Ukujonga amanqanaba e-ALT kunye namanqanaba ezinye i-enzyme zesibindi kunokubonelela ugqirha wakho ngolwazi oluthe kratya malunga nengxaki yesibindi.

Uvavanyo lwe-ALT lunokwenziwa kwakhona:

• jonga ukuqhubela phambili kwezifo zesibindi, ezinje nge-hepatitis okanye ukusilela kwesibindi
• kuvavanye ukuba ngaba unyango lwezifo zesibindi kufuneka luqalwe na
• vavanya ukuba lusebenza njani unyango

Ndilungiselela njani uvavanyo lwe-ALT?

Uvavanyo lwe-ALT alufuni lungiselelo luthile. Nangona kunjalo, kuya kufuneka uxelele ugqirha wakho malunga naluphi na amayeza okanye amayeza owathethayo. Amanye amachiza anokuchaphazela amanqanaba e-ALT egazini lakho. Ugqirha wakho unokukuxelela ukuba uphephe ukuthatha amayeza athile kangangexesha elithile phambi kovavanyo.

Uvavanyo lwe-ALT lwenziwa njani?

Uvavanyo lwe-ALT lubandakanya ukuthatha isampulu yegazi, njengoko kuchaziwe apha:

1. Umboneleli wezempilo usebenzisa i-antiseptic ukucoca ulusu lwakho kwindawo apho baya kufaka inaliti.
2. Zibopha ibhanti eyolukiweyo engalweni yakho ephezulu, ethintela ukuhamba kwegazi kwaye yenze imithambo engalweni yakho ibonakale ngakumbi.
3. Nje ukuba bafumane umthambo, bafaka inaliti emthanjeni. Oku kunokubangela ukucofa okufutshane okanye ukuqaqamba. Igazi litsalelwa kwityhubhu eqhotyoshelwe esiphelweni senaliti. Ngamanye amaxesha kunokufuneka ityhubhu engaphezulu kwesinye.
4. Emva kokuqokelelwa kwegazi elaneleyo, umboneleli wezempilo ususa ibhanti ebhetyebhetye kunye nenaliti. Bafaka isiqwenga somqhaphu okanye igeyile ngaphezulu kwesiza sokugqobhoza kwaye bayigqume ngebhandeji okanye iteyiphu ukuyigcina isendaweni yayo.
5. Isampulu yegazi ithunyelwa elabhoratri ukuze ihlolwe.
6. Ilabhoratri ithumela iziphumo zovavanyo kugqirha wakho. Ugqirha wakho unokucwangcisa idinga nawe ukuze bacacise iziphumo ngokweenkcukacha ezingaphezulu.

Zithini iingozi ezinxulumene novavanyo lwe-ALT?

I-ALT luvavanyo lwegazi olulula olunemingcipheko embalwa. Ukuqunjelwa ngamanye amaxesha kunokwenzeka kwindawo apho kufakwe inaliti. Umngcipheko wokugruzuka unokuncitshiswa ngokufaka uxinzelelo kwindawo yenaliti kangangemizuzu eliqela emva kokuba inaliti isusiwe.

Kwiimeko ezinqabileyo kakhulu, ezi ngxaki zilandelayo zinokwenzeka ngexesha okanye emva kovavanyo lwe-ALT:

• ukopha kakhulu apho kufakwe inaliti
• ingqokelela yegazi phantsi kolusu lwakho, ekuthiwa yihematoma
• ubukrwada okanye isiqaqa xa ujonga igazi
• usulelo kwindawo yokubhoboza

Zithetha ntoni iziphumo zam zovavanyo lwe-ALT?

Iziphumo eziqhelekileyo

Ixabiso eliqhelekileyo le-ALT kwigazi lisusela kwiiyunithi ezingama-29 ukuya kwezingama-33 ilitha nganye (IU / L) kumadoda nakwi-19 ukuya kuma-25 IU / L yabasetyhini, kodwa eli xabiso lingahluka ngokuxhomekeke esibhedlele. Olu luhlu lunokuchaphazeleka zizinto ezithile, kubandakanya isini kunye nobudala. Kubalulekile ukuxoxa ngeziphumo zakho ezithile nogqirha wakho.

Iziphumo ezingaqhelekanga

Amanqanaba aphezulu kune-ALT aphezulu kunokubonisa ukonakala kwesibindi. Ukunyuka kwamanqanaba e-ALT kunokuba sisiphumo se:

• hepatitis, nto leyo ukudumba kwesibindi
• i-cirrhosis, enesiva esibi esibindini
• ukufa kwezihlunu zesibindi
• ithumba okanye umhlaza esibindini
• ukunqongophala kokuhamba kwegazi esibindini
• I-hemochromatosis, sisifo esenza ukuba intsimbi yakheke emzimbeni
• mononucleosis, esisifo esihlala sibangelwa yintsholongwane ka-Epstein-Barr
• ukudumba kwengqondo, ukudumba kwepancreas
• isifo seswekile

Uninzi lweziphumo ze-ALT ezikumgangatho osezantsi zibonisa isibindi esisempilweni. Nangona kunjalo, zibonise ukuba iziphumo ezisezantsi kunesiqhelo zinxulumene nokwanda kwexesha elide lokufa kwabantu. Xoxa ngamanani akho ngokuthe ngqo nogqirha wakho ukuba unomdla wokufunda okuphantsi.

Ukuba iziphumo zakho zovavanyo zibonisa ukonakala kwesibindi okanye isifo, unokufuna uvavanyo oluninzi ukufumanisa oyena nobangela wengxaki kunye nendlela eyiyo yokuyinyanga.