Iindidi ze-Insulin ze-Insulin, izibonelelo, ulwazi lweDosi, kunye neziphumo ebezingalindelekanga

Umxholo

• Iindidi
• I-insulin esebenzayo phakathi, i-NPH
• I-insulin esebenza ixesha elide
• I-insulin ende esebenza ixesha elide
• Ukuqwalaselwa
• Izibonelelo
• Ulwazi lwedosi
• Ukuthatha i-NPH ngexesha lokulala, kusasa, okanye zombini
• Ukuthatha i-detemir, glargine, okanye i-degludec ngexesha lokulala
• Sebenzisa impompo ye-insulin
• Imiphumela
• Okukwintsusa

Umsebenzi ophambili we-basal insulin kukugcina amanqanaba eglucose egazini azinzile ngexesha lokuzila, njengaxa ulele. Ngelixa uzila ukutya, isibindi sakho ngokuqhubekayo sifihla iswekile egazini. I-insulin esisiseko igcina la mazinga eglucose phantsi kolawulo.

Ngaphandle kwale insulin, amanqanaba akho eglucose angenyuka ngeqondo elothusayo. I-insulin esisiseko iqinisekisa ukuba iiseli zakho zondliwa ngokuhamba rhoqo kweglucose ukutshisa amandla imini yonke.

Nantsi into ekufuneka uyazi malunga ne-basal insulin amayeza kwaye kutheni kubalulekile ukulawula isifo seswekile.

Iindidi

Zintathu iintlobo eziphambili ze-basal insulin.

I-insulin esebenzayo phakathi, i-NPH

Iinguqulelo zamagama eBrand ziquka uHumulin noNovolin. Le insulin ilawulwa kube kanye okanye kabini yonke imihla. Ihlala ixutywe nexesha lokutya i-insulin kusasa, ngaphambi kwesidlo sangokuhlwa, okanye zombini. Isebenza nzima kwiiyure ezi-4 ukuya kwezi-8 emva kwenaliti, kwaye iziphumo ziqala ukuncipha emva kweeyure ezili-16.

I-insulin esebenza ixesha elide

Iindidi ezimbini zale insulin okwangoku kwintengiso yi-detemir (Levemir) kunye ne-glargine (Toujeo, Lantus, kunye neBasaglar). Le insulin isisiseko iqala ukusebenza kwimizuzu engama-90 ukuya kwiiyure ezi-4 emva kwenaliti kwaye ihleli kwigazi lakho ukuya kuthi ga kwiiyure ezingama-24. Inokuqala ukubuthathaka kwiiyure ezimbalwa ngaphambili kwabanye abantu okanye ihlale iiyure ezimbalwa ixesha elide kwabanye. Akukho xesha liphezulu lolu hlobo lwe-insulin. Isebenza ngezinga elizinzileyo imini yonke.

I-insulin ende esebenza ixesha elide

NgoJanuwari 2016, enye i-basal insulin ebizwa nge-degludec (Tresiba) yakhutshwa. Le insulin isisiseko iqala ukusebenza kwisithuba semizuzu engama-30 ukuya kwengama-90 kwaye ihleli kwigazi lakho ukuya kuthi ga kwiiyure ezingama-42. Njengakwi-insulins esebenza ixesha elide i-detemir kunye ne-glargine, akukho xesha liphezulu lale insulin. Isebenza ngezinga elizinzileyo imini yonke.

I-insulin degludec iyafumaneka kumandla amabini, i-100 U / mL kunye ne-200 U / mL, ke kuya kufuneka uqiniseke ukuba uyayifunda ilebhile kwaye ulandele imiyalelo ngononophelo. Ngokungafaniyo ne-detemir kunye ne-glargine, inokudityaniswa nenye i-insulin esebenza ngokukhawuleza enokufikelela kwintengiso kungekudala.

Ukuqwalaselwa

Xa usenza isigqibo phakathi kwesiduli esiphakathi neside esisebenza ixesha elide, zininzi izinto ekufuneka ziqwalaselwe. Oku kubandakanya indlela ophila ngayo kunye nokuzimisela ukujova.

Umzekelo, unokuxuba i-NPH kunye nexesha lokutya le-insulin, ngelixa i-basal insulin esebenza ixesha elide kufuneka itofwe ngokwahlukeneyo. Izinto ezinokuchaphazela idosi yakho ye-insulin zibandakanya ubungakanani bomzimba wakho, amanqanaba ehomoni, ukutya, kunye nokuba ingakanani i-insulin yangaphakathi iipancreas zakho ezivelayo, ukuba zikhona.

Izibonelelo

Abantu abaninzi abanesifo seswekile njenge-basal insulin kuba ibanceda baphathe ngcono amanqanaba eswekile yegazi phakathi kokutya, kwaye ivumela indlela yokuphila eguqukayo.

Umzekelo, ukuba usebenzisa i-insulin esebenza ixesha elide, awunakukhathazeka malunga namaxesha aphezulu omsebenzi we-insulin. Oku kuthetha ukuba ixesha lokutya linokuguquguquka ngakumbi. Inokunciphisa umngcipheko wamanqanaba eswekile esezantsi egazi.

Ukuba uyasokola ukugcina amanqanaba eswekile ekujoliswe kuyo ekuseni, ukongeza i-basal insulin kwixesha lakho lokutya okanye ixesha lokulala kunokunceda ukusombulula le ngxaki.

Ulwazi lwedosi

Nge-basal insulin, unokukhetha iindlela ezintathu zedosi. Ukhetho ngalunye lunezinto ezilungileyo nezingalunganga. Izidingo zomntu wonke ze-insulin ezahlukileyo zahlukile, ke ugqirha wakho okanye ugqirha we-endocrinologist unokukunceda uthathe isigqibo sokuba yeyiphi idosi ekulungele.

Ukuthatha i-NPH ngexesha lokulala, kusasa, okanye zombini

Le ndlela inokubaluleka kuba i-insulin incopho ngexesha laphambi kwexesha nasemva kwemini, xa ifuneka kakhulu. Kodwa loo ncopho ayinakulindeleka ngokuxhomekeke kukutya kwakho, ixesha lokutya, kunye nenqanaba lomsebenzi. Oku kungakhokelela kumanqanaba eswekile esezantsi ngelixa ulele okanye usezantsi okanye uphezulu ushukela egazini ngexesha lasemini.

Ukuthatha i-detemir, glargine, okanye i-degludec ngexesha lokulala

Ukuhamba okungapheliyo kwezi insulini ezisebenza ixesha elide yenye yeenzuzo zazo eziphambili. Kodwa, abanye abantu bafumanisa ukuba i-detemir kunye ne-glargine insulin iyaphela ngokukhawuleza kuneeyure ezingama-24 emva kwenaliti. Oku kunokuthetha amanqanaba aphezulu eglucose kwigazi lakho elicwangcisiweyo elilandelayo. I-Degludec kufuneka ihlale ide inaliti yakho elandelayo ehleliweyo.

Sebenzisa impompo ye-insulin

Ngempompo ye-insulin, unokuhlengahlengisa inqanaba le-basal insulin ukuze ihambelane nokusebenza kwesibindi. Impazamo enye kunyango lwempompo ngumngcipheko wesifo seswekile ketoacidosis ngenxa yokungasebenzi kakuhle kwempompo. Nayiphi na ingxaki encinci yempompo inokubangela ukuba ungafumani isixa esifanelekileyo se-insulin.

Imiphumela

Ezinye zeempembelelo ezinokubakho ezinxulunyaniswa ne-basal insulin ibandakanya i-hypoglycemia kunye nokufumana ubunzima, nangona kunjalo ukuya kwinqanaba elincinci xa kuthelekiswa nezinye iintlobo ze-insulin.

Amachiza athile, kubandakanya i-beta-blockers, i-diuretics, i-clonidine, kunye ne-lithium salts, anokuzenza buthathaka iziphumo ze-basal insulin. Thetha nogqirha wakho kunye ne-endocrinologist malunga namayeza owathathayo ngoku kunye nolunye unxibelelwano lweziyobisi.

Okukwintsusa

I-insulin esisiseko yinto ebalulekileyo kulawulo lwakho lweswekile. Sebenza nogqirha wakho okanye i-endocrinologist ukufumanisa ukuba loluphi uhlobo olulungele wena kunye neemfuno zakho.