I-alkaline phosphatase: yintoni kwaye kutheni iphezulu okanye iphantsi

Umxholo

• Yenzelwe ntoni
• 1. I-alkaline phosphatase ephezulu
• 2. Phosphatase enealkali ephantsi
• Ulwenza nini uvavanyo
• Luqhutywa njani uviwo
• Amaxabiso esalathiso

I-alkaline phosphatase yi-enzyme ekhoyo kwizicubu zomzimba ezahlukeneyo, inenani elikhulu kwiiseli zemibhobho yenyongo, eyimizila ekhokelela inyongo ukusuka ngaphakathi esibindini ukuya emathunjini, yenza ukwetyiswa kwamafutha, nasemathanjeni, eveliswa ziiseli ezichaphazelekayo ekwakhiweni nasekugcinweni kwayo.

Uvavanyo lwe-alkaline phosphatase test ludla ngokusetyenziswa ekuphandeni izifo esibindini okanye emathanjeni, xa kukho iimpawu neempawu ezifana neentlungu esiswini, umchamo omnyama, isifo senyongo okanye ukukhubazeka kwamathambo kunye nentlungu, umzekelo. Inokwenziwa kwakhona njengovavanyo oluqhelekileyo, kunye nolunye uvavanyo, ukuze kuvavanywe impilo yesibindi.

Nangona kumanani asezantsi, i-alkaline phosphatase ikwakhona kwi-placenta, izintso kunye namathumbu kwaye ngenxa yoko inokuphakanyiswa xa ukhulelwe okanye kwimeko yokusilela kwezintso.

Yenzelwe ntoni

Uvavanyo lwe-alkaline phosphatase lusetyenziselwa ukuphanda ukuphazamiseka kwesibindi okanye kwethambo kwaye iziphumo zalo zinokuchonga:

1. I-alkaline phosphatase ephezulu

I-alkaline phosphatase inokuphakanyiswa xa kukho iingxaki kwisibindi ezinje:

• Ukuthintela ukuhamba kwe-bile, okubangelwa ngamatye enyongo okanye umhlaza, othintela imijelo ekhokelela inyongo emathunjini;

• IHepatitis, kukudumba kwesibindi okunokubangelwa ziintsholongwane, zintsholongwane okanye ziimveliso ezinetyhefu;

• I-Cirrhosis, esisifo esikhokelela ekutshatyalalisweni kwesibindi;

• Ukusetyenziswa kokutya okunamafutha;

• Ukungonelanga kwezintso.

Ukongeza, le enzyme inokuba phezulu kakhulu kwiimeko apho kukho ukwanda kwimisebenzi yokwenziwa kwethambo, ezinje ngezinye iintlobo zomhlaza wamathambo okanye kubantu abanesifo sikaPaget, esisifo esibonakaliswa kukukhula okungaqhelekanga kwethambo elithile iinxalenye. Funda kabanzi malunga nesifo sikaPaget.

Utshintsho oluncinci lunokubakho nangamaxesha okuphulukana nonyango, ukukhulelwa, uGawulayo, usulelo lwamathumbu, ihyperthyroidism, iHodgkin's lymphoma, okanye nasemva kokutya okunamafutha aphezulu.

2. Phosphatase enealkali ephantsi

Amanqanaba e-alkaline phosphatase manqabile aphantsi, nangona kunjalo le enzyme inokuhla kwezi meko zilandelayo:

• I-Hypophosphatasia, esisifo semfuza esibangela ukukhubazeka kunye nokuqhekeka emathanjeni;

• Ukungondleki;

• Ukusilela kweMagnesium;

• IHypothyroidism;

• Urhudo olukhulu;

• Anemia kakhulu.

Ukongeza, amanye amayeza anje ngeepilisi zokulawula ukuzalwa kunye neyeza zokunyanga iihormone ezisetyenzisiweyo ngexesha lokuya exesheni zinokubangela ukwehla kancinci kumanqanaba e-alkaline phosphatase.

Ulwenza nini uvavanyo

Uvavanyo lwe-alkaline phosphatase kufuneka lwenziwe xa iimpawu kunye neempawu zokuphazamiseka kwesibindi ezinje ngesisu esandisiweyo, iintlungu kwicala lasekunene lesisu, i-jaundice, umchamo omnyama, izitulo ezikhanyayo kunye nokurhawuzelela ngokubanzi.

Ukongeza, olu vavanyo lukwabonakalisiwe kubantu abaneempawu kunye neempawu kwinqanaba lamathambo anjengentlungu yethambo ngokubanzi, ukukhubazeka kwethambo okanye abo banengxaki yokuqhekeka.

Luqhutywa njani uviwo

Olu vavanyo lunokwenziwa elabhoratri, apho ingcali kwezempilo ithatha malunga ne-5 ml yesampulu yegazi emthanjeni engalweni, ebekwe kwisitya esivaliweyo, ukuze ihlalutywe.

Amaxabiso esalathiso

Amaxabiso ekubhekiswa kuwo kuvavanyo lwealkaline phosphatase ayahluka ngokobudala, ngenxa yokukhula:

Abantwana kunye nolutsha:

• <Iminyaka emibini: 85 - 235 U / L.
• Iminyaka emi-2 ukuya kweli-8: 65 - 210 U / L.
• Iminyaka eli-9 ukuya kweli-15: 60 - 300 U / L.
• Iminyaka eli-16 ukuya kwengama-21: 30 - 200 U / L.

Abantu abadala:

• 46 ukuya ku-120 U / L.

Ekukhulelweni, amaxabiso egazi e-alkaline phosphatase anokutshintshwa kancinci, ngenxa yokukhula komntwana kwaye ngenxa yokuba le enzyme ikwindawo ye-placenta.

Kunye nolu vavanyo, inokwenziwa nokuvavanywa kwezinye ii-enzymes ezifumaneka esibindini njenge-alanine aminotransferase, i-aspartate aminotransferase, i-gamma glutamyl transpeptidase kunye ne-bilirubins, iimvavanyo zokucinga okanye i-biopsy yesibindi. Jonga ukuba zenziwa njani na ezi mviwo.