Yintoni iLymphoma yefollicular?

Umxholo

• Iziganeko
• Iimpawu
• Uxilongo
• Unyango
• Ukulinda ulindile
• Imitha
• Unyango ngamayeza
• Amachiza omzimba monoclonal
• Unyango lwe-radioimmunotherapy
• Ukufakelwa kweseli
• Iingxaki
• Ukuchacha
• Imbonakalo

Ushwankathelo

I-lymphoma yesigxina luhlobo lomhlaza oqala kwiiseli ezimhlophe zegazi lomzimba wakho. Zimbini iindlela eziphambili ze-lymphoma: IHodgkin kunye ne-non-Hodgkin. I-lymphoma yesigxina ayiyiyo iHodgkin lymphoma.

Olu hlobo lwe-lymphoma ludla ngokukhula kancinci, abathi oogqirha balubize “ngokungakhathali.”

Funda ngokufunda ngakumbi malunga neempawu ze-follicular lymphoma kwaye loluphi ukhetho lonyango olukhoyo.

Iziganeko

I-non-Hodgkin lymphoma yenye yezona zomhlaza zixhaphakileyo eUnited States. Ngabantu abangaphezulu kwama-72,000 abafunyaniswa benayo nayiphi na indlela ngonyaka.

Phantse enye kwi-lymphomas ezintlanu e-United States yi-follicular lymphoma.

I-lymphoma yesigxina ayichaphazeli abantu abatsha. Iminyaka yobudala yomntu onolu hlobo lomhlaza imalunga nama-60.

Iimpawu

Iimpawu ze-follicular lymphoma zingabandakanya:

• i-lymph node ezandisiweyo entanyeni, ngaphantsi kweengalo, kwisisu okanye kwi-groin
• ukudinwa
• ukuqhawukelwa ngumphefumlo
• ifiva okanye ukubila ebusuku
• ukuhla ukusinda
• usulelo

Abanye abantu abane-follicular lymphoma abanazo kwaphela iimpawu.

Uxilongo

Ukuchonga i-follicular lymphoma, ugqirha wakho unokwenza ezi mvavanyo zilandelayo:

• Uqhaqho. I-biopsy yenziwa ukuvavanya izicwili phantsi kwemicroscope kwaye ichonge ukuba ingaba ngumhlaza na.
• Uvavanyo lwegazi. Unokufuna uvavanyo ukujonga ubalo lweeseli zakho zegazi.
• Ukujonga ukuskena. Ugqirha wakho unokucebisa ukuba ujonge umfanekiso ukuze ubone i-lymphoma emzimbeni wakho kunye nokucwangcisa unyango lwakho. Ikhompyuter ye-tomography (CT) kunye ne-positron emission tomography (PET) zisetyenziswa ngokuxhaphakileyo.

Unyango

Zininzi iindlela zokhetho ezikhoyo kubantu abane-lymphoma. Ugqirha wakho uya kuthatha isigqibo sokuba loluphi unyango olulungele wena ngokuxhomekeke kuhlobo lwakho lomhlaza kunye nokuba luqhubele phambili kangakanani.

Ukulinda ulindile

Ukuba ufunyaniswe kwangoko kwaye uneempawu ezimbalwa, ugqirha wakho unokucebisa ukuba ubukele kwaye ulinde. Oku kuthetha ukuba umboneleli wakho wezempilo uya kuhlala ejonge imeko yakho, kodwa awuyi kufumana naluphi na unyango okwangoku.

Imitha

Imitha isebenzisa imitha enamandla amakhulu ukutshabalalisa iiseli zomhlaza. Ihlala inikwa abantu abanesigaba sokuqala se-follicular lymphoma. Ngamanye amaxesha, i-radiation iyodwa inokukwazi ukunyanga olu hlobo lomhlaza. Unokufuna i-radiation kunye nezinye iindlela zonyango ukuba umhlaza wakho uqhubele phambili.

Unyango ngamayeza

I-Chemotherapy isebenzisa iziyobisi ukubulala iiseli zomhlaza emzimbeni wakho. Ngamanye amaxesha kunikwa abantu abane-follicular lymphoma, kwaye ihlala idityaniswa nolunye unyango.

Amachiza omzimba monoclonal

Ama-antibodies e-monoclonal ngamayeza ajolise ekumakishineni ngokukodwa kwizidumbu kwaye anceda iiseli zakho zokhuselo lomzimba zilwe nomhlaza. I-Rituximab (i-Rituxan) yi-anti-monoclonal antibody esetyenziswa ngokunyanga njenge-follicular lymphoma. Ngokwesiqhelo kunikwa ukumiliselwa kwe-IV kwiofisi kagqirha wakho kwaye ihlala isetyenziswa ngokudibanisa ne-chemotherapy.

Umdibaniso oqhelekileyo ubandakanya:

• r-bendamustine (rituximab kunye ne-bendamustine)
• R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, kunye ne-prednisone)
• R-CVP (rituximab, cyclophosphamide, vincristine, kunye ne-prednisone)

Unyango lwe-radioimmunotherapy

I-Radioimmunotherapy ibandakanya ukusebenzisa iyeza i-yttrium-90 ibritumomab tiuxetan (Zevalin) ukuhambisa imitha kwiiseli zomhlaza.

Ukufakelwa kweseli

Ngamanye amaxesha ukufakelwa iselfowuni kusetyenziselwa i-follicular lymphoma, ngakumbi ukuba umhlaza ubuya. Le nkqubo ibandakanya ukufakela iiseli ezinempilo emzimbeni wakho ukubuyisela umongo wethambo onesifo.

Zimbini iintlobo zokufakelwa kweseli:

• Ukufakelwa ngokuzenzekelayo. Le nkqubo isebenzisa iiseli zakho zokunyanga umhlaza wakho.
• Ukufakelwa kweAllogeneic. Le nkqubo isebenzisa iiseli ezinempilo ezivela kumnikeli.

Iingxaki

Xa i-lymphoma ekhula kancinci, njenge-follicular lymphoma, ijika ibe yifom ekhula ngokukhawuleza, yaziwa ngokuba yi-lymphoma eguqulweyo. I-lymphoma eguqulweyo ihlala inoburhalarhume kwaye inokufuna unyango olungqongqo.

Ezinye ii-lymphomas ezinokulandelwa zinokujika zibe luhlobo olukhula ngokukhawuleza lwe-lymphoma ebizwa ngokuba yi-B-cell lymphoma enkulu.

Ukuchacha

Emva konyango oluyimpumelelo, abantu abaninzi abane-follicular lymphoma baya kuxolelwa. Nangona oku kuxolelwa kunokuhlala iminyaka, i-follicular lymphoma ithathwa njengemeko yobomi bonke.

Lo mhlaza ungabuya, kwaye ngamanye amaxesha, abantu ababuyela umva abaphenduli kunyango.

Imbonakalo

Unyango lwe-follicular lymphoma zihlala zisetyenziselwa ukugcina isifo siphantsi kolawulo kunokunyanga imeko. Lo mhlaza uhlala ulawulwa ngempumelelo iminyaka emininzi.

Oogqirha baphuhlise iFollicular Lymphoma International Prognostic Index (FLIPI) ukunceda ukubonelela ngolu hlobo lomhlaza. Le nkqubo inceda ukwahlula i-follicular lymphoma kwiindidi ezintathu:

• umngcipheko ophantsi
• umngcipheko ophakathi
• umngcipheko omkhulu

Umngcipheko wakho ubalwa ngokusekwe "kwizinto zakho zokuxela kwangaphambili," ezibandakanya izinto ezifana nobudala, inqanaba lomhlaza wakho, kunye nokuba zingaphi ii-lymph node ezichaphazelekayo.

Ireyithi yokusinda yeminyaka emihlanu yabantu abane-follicular lymphoma abasemngciphekweni ophantsi (abanakho okanye inye kuphela into engalunganga yokuxela kwangaphambili) imalunga neepesenti ezingama-91. Kulabo abanomngcipheko ophakathi (izinto ezimbini ezimbi zokuxela), izinga lokusinda leminyaka emihlanu liipesenti ezingama-78. Ukuba usemngciphekweni omkhulu (ezintathu okanye nangaphezulu iimeko zokuxela), izinga lokusinda leminyaka emihlanu liipesenti ezingama-53.

Amaxabiso okusinda anokunika ulwazi oluluncedo, kodwa ziingqikelelo kuphela kwaye azinako ukuqikelela ukuba kuya kwenzeka ntoni kwimeko yakho ethile. Thetha nogqirha wakho malunga nembono yakho ethile kwaye zeziphi izicwangciso zonyango ezifanelekileyo kwimeko yakho.