Uvavanyo lweHaptoglobin (HP)

Umxholo

• Yintoni uvavanyo lweHaptoglobin (HP)?
• Isetyenziselwa ntoni?
• Kutheni ndifuna uvavanyo lwe-haptoglobin?
• Kwenzeka ntoni ngexesha lovavanyo lwe-haptoglobin?
• Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?
• Ngaba bukhona ubungozi kuvavanyo lwe-haptoglobin?
• Zithetha ntoni iziphumo?
• Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwe-haptoglobin?
• Izalathiso

Yintoni uvavanyo lweHaptoglobin (HP)?

Olu vavanyo lilinganisa inani le-haptoglobin egazini. IHaptoglobin yiprotein eyenziwe sisibindi sakho. Inamathela kuhlobo oluthile lwehemoglobin. IHemoglobin yiprotein ekwiiseli ezibomvu zegazi ezithwala ioksijini kwimiphunga yakho iye kumzimba wakho uphela. Uninzi lwe-hemoglobin lubekwe ngaphakathi kwiiseli ezibomvu zegazi, kodwa amanani amancinci ajikeleza kwigazi. I-Haptoglobin ibophelela kwi-hemoglobin egazini. Ngokudibeneyo, ezi proteni zimbini zibizwa ngokuba yihaptoglobin-hemoglobin complex. Obu bunzima bususwa ngokukhawuleza kwigazi kwaye bususwe emzimbeni sisibindi sakho.

Xa iiseli ezibomvu zegazi zonakalisa, zikhupha i-hemoglobin engakumbi egazini. Oko kuthetha ukuba uninzi lwe-haptoglobin-hemoglobin complex iya kucocwa emzimbeni. I-haptoglobin inokushiya umzimba ngokukhawuleza kunokuba isibindi sinokuwenza. Oku kubangela ukuba amanqanaba egazi e-haptoglobin ehle. Ukuba amanqanaba akho e-haptoglobin asezantsi kakhulu, kunokuba luphawu lokuphazamiseka kweeseli ezibomvu zegazi, ezinje ngeanemia.

Amanye amagama: iproteni ebopha i-hemoglobin, HPT, Hp

Isetyenziselwa ntoni?

Uvavanyo lwe-haptoglobin luhlala lusetyenziselwa ukuxilonga i-hemolytic anemia. I-hemolytic anemia sisifo esenzeka xa iiseli zakho ezibomvu zitshatyalalisiwe ngokukhawuleza kunokuba zinokubuyiselwa endaweni yazo. Olu vavanyo lungasetyenziselwa ukubona ukuba ngaba olunye uhlobo lwe-anemia okanye olunye ukuphazamiseka kwegazi lubangela iimpawu zakho.

Kutheni ndifuna uvavanyo lwe-haptoglobin?

Unokulufuna olu vavanyo ukuba uneempawu ze-anemia. Oku kubandakanya:

• Ukudinwa
• Ulusu oluthuthu
• Ukuqhawukelwa ngumphefumlo
• Inqanaba lentliziyo elikhawulezayo
• IJaundice, imeko ebangela ukuba ulusu namehlo akho ajike abe tyheli
• Umchamo omnyama ngombala

Unokulufuna olu vavanyo ukuba ngaba uye watofelwa igazi. Uvavanyo lunokwenziwa ngolunye uvavanyo olubizwa ngokuba yi-anti-globulin ngqo. Iziphumo zolu vavanyo zinokubonisa ukuba ngaba uye wasabela kakubi kutofelo-gazi.

Kwenzeka ntoni ngexesha lovavanyo lwe-haptoglobin?

Ingcali yokhathalelo lwempilo iyakuthatha isampulu yegazi kumthambo engalweni yakho, isebenzisa inaliti encinci. Emva kokuba inaliti ifakiwe, inani elincinci legazi liya kuqokelelwa kwityhubhu yovavanyo okanye igutyana. Unokuziva uluma kancinci xa inaliti ingena okanye iphuma. Oku kuhlala kuthatha imizuzu engaphantsi kwesihlanu.

Ngaba kuya kufuneka ndenze nantoni na ukulungiselela uvavanyo?

Awudingi naluphi na ulungiselelo olukhethekileyo lovavanyo lwe-haptoglobin.

Ngaba bukhona ubungozi kuvavanyo lwe-haptoglobin?

Mncinci kakhulu umngcipheko wokuvavanywa kwegazi. Unokuba nentlungu encinci okanye ukrakra kwindawo apho inaliti yafakwa khona, kodwa uninzi lweempawu zihamba ngokukhawuleza.

Zithetha ntoni iziphumo?

Ukuba iziphumo zakho zibonisa ukuba amanqanaba akho e-haptoglobin asezantsi kunesiqhelo, oko kunokuthetha ukuba unale miqathango ilandelayo:

• I-anemia yeHemolytic
• Isifo sesibindi
• Ukusabela kutofelo-gazi

Umboneleli wakho wezempilo unokuyalela ezinye iimvavanyo zegazi ukunceda ukwenza uxilongo. Oku kubandakanya:

• Ukubala kweReticulocyte
• Uvavanyo lwehemoglobin
• Uvavanyo lweHematocrit
• Uvavanyo lweLactate Dehydrogenase
• Igazi lokuthambisa
• Gcwalisa ubalo lwegazi

Olu vavanyo lunokwenziwa ngaxeshanye okanye emva kovavanyo lwakho lwe-haptoglobin.

Ukuba unemibuzo malunga neziphumo zakho, thetha nomboneleli wakho wezempilo.

Funda ngakumbi malunga novavanyo lwelabhoratri, uluhlu lweereferensi, kunye neziphumo zokuqonda.

Ngaba ikhona enye into endifuna ukuyazi malunga novavanyo lwe-haptoglobin?

Amanqanaba aphezulu e-haptoglobin angangumqondiso wesifo esidumbisayo. Izifo ezivuthayo kukuphazamiseka kwamajoni omzimba kunokubangela iingxaki zempilo. Kodwa uvavanyo lwe-haptoglobin alusoloko lusetyenziselwa ukuxilonga okanye ukubeka esweni iimeko ezinxulumene namanqanaba aphezulu e-haptoglobin.

Izalathiso

1. Umbutho waseMelika weHematology [kwi-Intanethi]. IWashington DC: Umbutho waseMelika weHematology; c2020. Anemia; [icatshulwe ngo-2020 kuMatshi 4]; [malunga nezikrini ezi-3]. Ifumaneka kwi: http://www.hematology.org/Patients/Anemia
2. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC: Umbutho waseMelika weKlinikhi yeKhemistry; c2001-2020. Haptoglobin; [ihlaziyiwe ngo-2019 Sep 23; icatshulwe ngo-2020 kuMatshi 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/tests/haptoglobin
3. Uvavanyo lweLebhu kwi-Intanethi [kwi-Intanethi]. IWashington DC: Umbutho waseMelika weKlinikhi yeKhemistry; c2001-2020. IJaundice; [ihlaziywe ngo-2019 Oktobha 30; icatshulwe ngo-2020 kuMatshi 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://labtestsonline.org/conditions/jaundice
4. Impilo yeMaine [kwi-Intanethi]. IPortland (ME): Impilo yaseMaine; c2020. Ukudumba / ukuDumba; [icatshulwe ngo-2020 kuMatshi 4]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://mainehealth.org/services/autoimmune-diseases-rheumatology/infigueatory-diseases
5. Intliziyo kaZwelonke, iMiphunga, kunye neZiko leGazi [kwi-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Uvavanyo lwegazi; [icatshulwe ngo-2020 kuMatshi 4]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.nhlbi.nih.gov/health-topics/blood-tests
6. Intliziyo kaZwelonke, iMiphunga, kunye neZiko leGazi [kwi-Intanethi]. I-Bethesda (MD): Isebe lezeMpilo laseMelika kunye neeNkonzo zoLuntu; Anemia yeHemolytic; [icatshulwe ngo-2020 kuMatshi 4]; [malunga nezikrini ezi-3]. Ifumaneka kwi: https://www.nhlbi.nih.gov/health-topics/hemolytic-anemia
7. UShih AW, uMcFarlane A, uVerhovsek M.Uvavanyo lweHaptoglobin kwi-hemolysis: ukulinganisa nokutolika. NdinguJ Hematol [kwi-Intanethi]. 2014 uEpreli [ucatshulwe ngowe-2020 kuMatshi 4]; Ngama-89 (4): 443-7. Ifumaneka kwi: https://www.ncbi.nlm.nih.gov/pubmed/24809098
8. Impilo ye-UF: iYunivesithi yaseFlorida yezeMpilo [i-Intanethi]. IGainesville (FL): yeYunivesithi yaseFlorida yezeMpilo; c2020. Uvavanyo lwegazi lweHaptoglobin: Ubume; [ihlaziyiwe ngo-2020 nge-4 kaMatshi; icatshulwe ngo-2020 kuMatshi 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://ufhealth.org/winaoglobin-blood-test
9. IYunivesithi yaseRochester Medical Centre [i-Intanethi]. URochester (NY): KwiYunivesithi yaseRochester Medical Centre; c2020. Health Encyclopedia: IHaptoglobin; [icatshulwe ngo-2020 kuMatshi 4]; [malunga nezikrini ezi-2]. Ifumaneka kwi: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=operaoglobin

Ulwazi olukule ndawo akufuneki lusetyenziswe endaweni yonyango okanye iingcebiso. Nxibelelana nomboneleli wezempilo ukuba unemibuzo malunga nempilo yakho.