IHydroxychloroquine: yintoni, iyintoni kunye neziphumo ebezingalindelekanga

Umxholo

• Kusetyenziswa kwanjani
• 1. Inkqubo ye-lupus erythematosus yenkqubo kunye ne-discoid
• 2. I-rheumatoid kunye ne-arthritis yabantwana
• 3. Izifo ezingafunekiyo
• 4. Isifo seengcongconi
• Ngaba i-hydroxychloroquine iyacetyiswa ukuba inyangelwe usulelo lwe-coronavirus?
• Ngubani ongafanele asebenzise
• Iziphumo ebezingalindelekanga ezinokwenzeka

IHydroxychloroquine sisiyobisi esiboniswe kunyango lwe-rheumatoid arthritis, lupus erythematosus, dermatological kunye ne-rheumatic kunye nokunyanga isifo seengcongconi.

Le into esebenzayo ithengiswa ngorhwebo phantsi kwegama elithi Plaquinol okanye iReuquinol, kwaye inokuthengwa ezikhemesti ngexabiso elimalunga nama-65 ukuya kuma-85 reais, xa kunikwa amayeza.

Kusetyenziswa kwanjani

Umthamo wehydroxychloroquine uxhomekeke kwingxaki eza kunyangwa:

1. Inkqubo ye-lupus erythematosus yenkqubo kunye ne-discoid

Idosi yokuqala yehydroxychloroquine yi-400 ukuya kwi-800 mg ngosuku kwaye idosi yokugcina ingama-200 ukuya kuma-400 mg ngosuku. Funda ukuba yintoni i-lupus erythematosus.

2. I-rheumatoid kunye ne-arthritis yabantwana

Idosi yokuqala yi-400 ukuya kwi-600 mg ngosuku kwaye idosi yokugcina ingama-200 ukuya kuma-400 mg ngosuku. Yazi iimpawu zesifo samathambo kunye nendlela esinyangwa ngayo.

Umthamo wesifo samathambo esingapheliyo solutsha akufuneki udlule kwi-6.5 mg / kg yesisindo ngosuku, ukuya kuthi ga kwiqondo eliphezulu le-400 mg yemihla ngemihla.

3. Izifo ezingafunekiyo

Idosi ekhuthazwayo yi-400 mg / ngosuku ekuqaleni kwaye yehliswe yaya kwi-200 mg ngosuku. Ngokufanelekileyo, unyango kufuneka luqale kwiintsuku ezimbalwa ngaphambi kokuvezwa lilanga.

4. Isifo seengcongconi

• Unyango olucinezelayo: Kubantu abadala, idosi ekhuthazwayo yi-400 mg ngeveki kwaye ebantwaneni yi-6.5 mg / kg ubunzima bomzimba ngeveki.Unyango kufuneka luqaliswe kwiiveki ezi-2 ngaphambi kokuvezwa okanye, ukuba oku akunakwenzeka, kunokuba yimfuneko ukulawula idosi yokuqala ye-800 mg kubantu abadala kunye ne-12.9 mg / kg kubantwana, yahlulwe yangamayeza amabini, kunye neeyure ezingama-6 zonyango. . Unyango kufuneka luqhubeke iiveki ezisi-8 emva kokushiya indawo ebubukho bayo.
• Unyango lweengxaki ezibi: Kubantu abadala, idosi yokuqala yi-800 mg elandelwa yi-400 mg emva kweeyure ezingama-6 ukuya kwezi-8 kunye ne-400 mg yonke imihla ngeentsuku ezimbini ezilandelelanayo okanye, kungenjalo, idosi enye ye-800 mg inokuthathwa. Kubantwana, idosi yokuqala ye-12.9 mg / kg kunye nedosi yesibini ye-6.5 mg / kg kufuneka inikezelwe kwiiyure ezintandathu emva kwethamo lokuqala, idosi yesithathu ye-6.5 mg / kg kwiiyure ezili-18 emva kwethamo lesibini kunye nedosi yesine ye-6.5 mg / kg, iiyure ezingama-24 emva kwethamo lesithathu.

Ngaba i-hydroxychloroquine iyacetyiswa ukuba inyangelwe usulelo lwe-coronavirus?

Emva kokuqhuba izifundo ezininzi zesayensi, kwagqitywa ekubeni i-hydroxychloroquine ayikhuthazwa kunyango losulelo kwi-coronavirus entsha. Kutshanje kubonisiwe, kuvavanyo lweklinikhi oluqhutyelwe kwizigulana ezine-COVID-19, ukuba eli chiza libonakala lingenazibonelelo, ukongeza ekuphindaphindeni kweziphumo ebezingalindelekanga ezibi kunye nokufa, okukhokelele ekunqunyanyisweni okwethutyana kwezilingo zeklinikhi zazisenzeka kwamanye amazwe ngeyeza.

Nangona kunjalo, iziphumo zolu vavanyo ziyahlalutywa, ukuze kuqondwe indlela yokusebenza kunye nokuthembeka kwedatha, kude kube kukhuselekile kwesiyobisi. Funda ngakumbi malunga neziphumo zophando olwenziwe ngehydroxychloroquine kunye nezinye iziyobisi ngokuchasene ne-coronavirus entsha.

Ngokuka-Anvisa, ukuthengwa kwehydroxychloroquine ekhemesti kusavumelekile, kodwa kuphela kubantu abanemigqaliselo yezonyango yezi zifo sele zikhankanyiwe kunye nezinye iimeko ezazibonisa iyeza phambi kobhubhane we-COVID-19. Ukuzinyanga ngokwakho kunokuba neziphumo ezibi empilweni, ke ngaphambi kokuba uthathe naliphi na iyeza kufuneka uthethe nogqirha.

Ngubani ongafanele asebenzise

I-Hydroxychloroquine akufuneki isetyenziswe ngabantu abanovelwano kakhulu nakweziphi na izinto ezikhoyo kwifomula, kunye ne-retinopathies esele ikhona okanye abangaphantsi kweminyaka emi-6 ubudala.

Iziphumo ebezingalindelekanga ezinokwenzeka

Iziphumo eziqhelekileyo ezinokubakho ngokusetyenziswa kweli nyango yi-anorexia, intloko ebuhlungu, ukuphazamiseka kombono, iintlungu zesisu, isicaphucaphu, isifo sorhudo, ukugabha, ukurhawuzelela kunye nokurhawuzelela.