Hyperpituitarism

Umxholo

• Ushwankathelo
• Iimpawu
• Yintoni unobangela?
• Izinketho zonyango
• Amayeza
• Ugqirha
• Imitha
• Kufunyaniswa njani?
• Iingxaki kunye neemeko ezinxulumene nazo
• Imbonakalo

Ushwankathelo

Idlala lengqula sisifo esincinci esisezantsi kwengqondo yakho. Imalunga nobungakanani bepea. Yindlala ye-endocrine. Imeko ye-hyperpituitarism yenzeka xa eli dlala liqala ukuvelisa ngaphezulu iihomoni. Idlala lengqula livelisa iihomoni ezilawula eminye yemisebenzi ephambili yomzimba wakho. Le misebenzi iphambili yomzimba ibandakanya ukukhula, uxinzelelo lwegazi, imetabolism, kunye nokusebenza ngokwesondo.

I-Hyperpituitarism inokuchaphazela kakubi imisebenzi emininzi yomzimba wakho. Oku kunokubandakanya:

• umgaqo wokukhula
• Ukufikisa kubantwana
• nombala wolusu
• umsebenzi wesondo
• imveliso yobisi lwebele kubafazi abancancisayo
• umsebenzi we-thyroid
• ukuzala

Iimpawu

Iimpawu zehyperpituitarism ziyahluka ngokuxhomekeka kwimeko ebangela oko. Siza kujonga imeko nganye kunye neempawu ezihamba nazo ngokukodwa.

Iimpawu zeCushing syndrome zinokubandakanya oku kulandelayo:

• amafutha amaninzi emzimbeni
• inani elingaqhelekanga leenwele zobuso kwabasetyhini
• ukutyunyuzwa ngokulula
• amathambo aqhekeka lula okanye aethe-ethe
• Iimpawu zokolula isisu ezimfusa okanye ezipinki

Iimpawu ze-gigantism okanye i-acromegaly inokubandakanya oku kulandelayo:

• izandla neenyawo ezikhula zibe nkulu
• ukwandiswa okanye ukubonakala kobuso ngokungaqhelekanga
• iithegi zolusu
• Ivumba lomzimba nokubila okugqithisileyo
• ubuthathaka
• ilizwi elinomsindo
• intloko ebuhlungu
• ulwimi olwandisiweyo
• iintlungu ezidibeneyo kunye nentshukumo encinci
• umphanda esifubeni
• amaxesha angaqhelekanga
• Ukungasebenzi kakuhle kwe-erectile

Iimpawu zegalactorrhea okanye iprolactinoma inokubandakanya oku kulandelayo:

• amabele athambileyo kubafazi
• amabele aqala ukuvelisa ubisi kwabasetyhini abangakhulelwanga kwaye kunqabile emadodeni
• Umsebenzi wokuzala
• ixesha elingaqhelekanga okanye ukuyeka ukuya exesheni
• ukungachumi
• isini esisezantsi
• Ukungasebenzi kakuhle kwe-erectile
• amandla aphantsi

Iimpawu zehyperthyroidism zinokubandakanya oku kulandelayo:

• ixhala okanye uvalo
• ukukhawuleza kwentliziyo
• ukubetha kwentliziyo okungaqhelekanga
• ukudinwa
• ubuthathaka bemisipha
• ukwehla kobunzima

Yintoni unobangela?

Ukungasebenzi kakuhle kwi-pituitary gland njenge-hyperpituitarism kunokwenzeka ukuba kubangelwa yithumba. Uhlobo oluqhelekileyo lwethumba kuthiwa yi-adenoma kwaye alunomdlavuza. Ithumba linokubangela ukuba i-pituitary gland ivelise kakhulu iihomoni. Ithumba, okanye ulwelo oluzalisa macala onke, lunokucinezela nakwidlala yebhinqa. Olu xinzelelo lunokubangela ukuba i-hormone eninzi iveliswe okanye incinci kakhulu ukuba iveliswe, ebangela i-hypopituitarism.

Unobangela wezi ntlobo zamathumba awaziwa. Nangona kunjalo, unobangela wethumba unokuba lilifa. Ezinye izicubu zelifa zibangelwa yimeko eyaziwa njengee-endocrine neoplasia syndromes.

Izinketho zonyango

Unyango lwe-hyperpituitarism luya kwahluka ngokujonga isifo esikubonayo. Nangona kunjalo, unyango lunokubandakanya enye okanye ezingaphezulu kwezi zilandelayo:

Amayeza

Ukuba ithumba libangela i-hyperpituitarism yakho emva koko amayeza anokusetyenziselwa ukunciphisa. Oku kunokwenziwa ngaphambi kotyando ukususa ithumba. Amayeza anokuphinda asetyenziswe kwi-tumor ukuba utyando alunakukhetha kuwe. Kwezinye iimeko ze-hyperpituitarism, amayeza anokunceda ukubaphatha okanye ukubalawula.

Imiqathango enokufuna amayeza olawulo okanye unyango ibandakanya:

• Prolactinoma. Amayeza angathoba amanqanaba akho eprolactin.
• Acromegaly okanye gigantism. Amayeza anokuhlisa isixa sokukhula kwamahomoni.

Ugqirha

Utyando lwenziwa ukuze kususwe ithumba kwincindi yebhinqa. Olu hlobo lotyando lubizwa ngokuba yi-transsphenoidal adenomectomy. Ukususa ithumba, ugqirha wakho wotyando uya kwenza ukusikwa okuncinci kumlomo wakho ongaphezulu okanye empumlweni. Olu qhekeko luya kuvumela ugqirha ukuba afike kwi-pituitary gland kwaye asuse ithumba. Xa lwenziwe ngugqirha onamava, olu hlobo lotyando lunempumelelo engaphezulu kweepesenti ezingama-80.

Imitha

Imitha yenye yeendlela ukuba awukwazi ukwenza utyando ukuze ususe ithumba. Inokukunceda ekususeni nasiphi na isicwili sethumba esisenokuba sishiyeke ngasemva kuqhaqho lwangaphambili. Ukongeza, i-radiation inokusetyenziselwa izilonda ezingaphenduliyo kumayeza. Zimbini iintlobo zemitha enokusetyenziswa:

• Unyango oluqhelekileyo lwemitha. Amayeza amancinci anikwa ngaphezulu kweeveki ezine ukuya kwezintandathu. Izicubu ezijikelezileyo zinokonakala ngeli xesha lonyango lwemitha.
• Unyango lwe-stereotactic. Umqadi wemitha yedosi ephezulu ijolise kwithumba. Oku kuhlala kwenziwa kwiseshoni enye. Xa kwenziwe kwiseshoni enye, mancinci amathuba okonakalisa izicwili ezijikelezileyo. Isenokufuna unyango oluqhubekayo lwehomoni emva koko.

Kufunyaniswa njani?

Uvavanyo lokuqonda isifo lwehyperpituitarism luyahluka ngokuxhomekeka kwiimpawu zakho kunye nembali yezonyango. Emva kokuxoxa ngeempawu zakho kunye nokunika uvavanyo lomzimba, ugqirha wakho uya kugqiba ukuba zeziphi iimvavanyo zokuqonda ekufuneka zisetyenzisiwe. Uhlobo lovavanyo lunokubandakanya:

• iimvavanyo zegazi
• uvavanyo lokunyamezelana ngeswekile yomlomo
• iimvavanyo ezikhethekileyo zesampulu yegazi
• iimvavanyo zokucinga ngomfanekiso we-MRI okanye we-CT ukuba kurhanelwa ithumba

Ugqirha wakho unokusebenzisa enye okanye indibanisela yolu vavanyo ukuza kuvavanyo olufanelekileyo.

Iingxaki kunye neemeko ezinxulumene nazo

I-Hyperpituitarism inokubangela iimeko ezahlukeneyo. Le miqathango ibandakanya oku kulandelayo:

• Isifo seCushing
• ubungqingili okanye i-acromegaly
• galactorrhea okanye iprolactinoma
• hyperthyroidism

Iingxaki ze-hyperpituitarism ziyahluka ngokuxhomekeka kwimeko ebangelwe yiyo. Enye yeengxaki ezinokubakho emva kotyando lokususa ithumba kukuba unokuba nesidingo esiqhubekayo sokuthatha amayeza onyango.

Imbonakalo

Imbonakalo yabo bane-hyperpituitarism ilungile. Ezinye zeemeko ezinokubangela ziya kufuna amayeza aqhubekayo kulawulo olufanelekileyo lweempawu. Nangona kunjalo, inokulawulwa ngempumelelo ngononophelo olufanelekileyo, utyando xa kufuneka, kunye namayeza njengoko kuyalelwe. Ukufumana unyango olufanelekileyo kunye nolawulo, kuya kufuneka uqiniseke ngokubonisana neengcali zonyango ezinamava nge-hyperpituitarism.