Ngaba akulunganga ukuthatha i-Ibuprofen kwisisu esingenanto?

Umxholo

• Ngaba kukhuselekile kwisisu esingenanto?
• Okungakumbi malunga nebuprofen
• Imiphumela
• Kufuneka wenze ntoni ukuba sele uyithathile
• Yeyiphi indlela ebalaseleyo yokuthatha ibuprofen?
• Nini ukubona ugqirha
• Umgca wezantsi

I-Ibuprofen yenye yezona zinto zixhaphake kakhulu kwi-counter-the-counter (OTC) amayeza asetyenziselwa ukunyanga iintlungu, ukudumba kunye nomkhuhlane. Sekuyiminyaka engama-50.

I-Ibuprofen sisiyobisi esichasayo (i-NSAID), kwaye isebenza ngokuthintela umsebenzi we-cyclooxygenase (COX) enzyme. Umsebenzi we-COX ujongene nemveliso yeprostaglandin.

Nokuba ibuprofen ikhuselekile ukuthatha isisu esingenalutho ixhomekeke ikakhulu emngciphekweni ngamnye kunye nomngcipheko othile.

Masiqwalasele ngokusondeleyo indlela efanelekileyo yokuthatha ibuprofen ukuphucula iimpawu ngelixa unciphisa umngcipheko.

Ngaba kukhuselekile kwisisu esingenanto?

I-Ibuprofen inokubangela iziphumo ezibi zesisu esiswini (GI) ngokubanzi. Nangona kunjalo, ingozi ikhona kwaye ixhomekeke kubudala bomntu, ubude bokusetyenziswa, idosi, kunye nazo naziphi na iingxaki zempilo ezikhoyo.

I-Ibuprofen inokuchaphazela amanqanaba e-prostaglandin kwaye ibangele iziphumo ebezingalindelekanga ze-GI. Umsebenzi omnye we-prostaglandin kukukhusela isisu sayo. Iyanciphisa isisu esiswini kwaye inyuse imveliso ye-mucus.

Xa ibuprofen ithathwa ngeedosi ezinkulu okanye ixesha elide, iveliswa i-prostaglandin encinci. Oku kunokunyusa isisu esiswini kwaye kuyicaphukise ingaphakathi lesisu, kubangele iingxaki.

Iziphumo ebezingalindelekanga ze-GI zixhomekeka kwizinto ezininzi, kubandakanya:

• Ubude bokusetyenziswa. Xa uthatha ibuprofen ixesha elide, umngcipheko weengxaki ezinxulumene ne-GI, xa kuthelekiswa nokusetyenziswa kwexesha elifutshane kwiimfuno ezikhawulezileyo.
• Ithamo. Ukuthatha iidosi eziphezulu ixesha elide kunyusa umngcipheko weengxaki ezinxulumene ne-GI.
• Ezinye iimeko zempilo. Ukuba neemeko ezithile zempilo, ezinje ngezi zilandelayo, kunokunyusa umngcipheko weziphumo ebezingalindelekanga okanye iimpendulo ezibi:
  • Imbali yezikhalazo ze-GI
  • izilonda ezophayo
  • isifo sesisu esingapheliyo
• Imiba nganye. Abantu abadala banomngcipheko ophezulu we-GI kunye nezinye iziphumo ebezingalindelekanga ngokusetyenziswa kwe-ibuprofen.
  • Qiniseka ukuba uxoxa ngezibonelelo ze-ibuprofen xa uthelekisa nayiphi na ingozi nogqirha wakho ngaphambi kokuba uthathe eli yeza.
  • Ukuba unentliziyo, izintso, uxinzelelo lwegazi oluphezulu, okanye ezinye iimeko zonyango ezingapheliyo, buza ugqirha wakho malunga nokusetyenziswa kwe-ibuprofen.

Okungakumbi malunga nebuprofen

Zimbini iintlobo ezahlukileyo ze-COX, kwaye zinomzimba. I-COX-2, xa yenziwe yasebenza, iibhloko ze-prostaglandin zikhutshwa ekuphenduleni iintlungu, umkhuhlane kunye nokudumba. I-COX-1 inefuthe lokukhusela kwisisu esiswini kunye neeseli eziyingqongileyo

I-Ibuprofen ichaphazela zombini i-COX-1 kunye nomsebenzi we-COX-2, ukubonelela ngesiqabu seempawu kwaye kwangaxeshanye kwandisa umngcipheko weziphumo ebezingalindelekanga ezithile.

unokwenza umahluko ngokufunxa, ukusebenza kakuhle, kunye neziphumo ebezingalindelekanga. Oku kubandakanya ukuyithatha kunye nokutya okanye isisu esingenanto.

Omnye wemiceli mngeni nge-ibuprofen kukuba xa uyithatha ngomlomo, ayifunxi ngokukhawuleza. Kuthatha malunga nemizuzu engama-30 ukusebenza. Oku kubalulekile xa ufuna ukukhululeka kwentlungu kwangoko.

Imiphumela

I-Ibuprofen inokubangela iziphumo ebezingalindelekanga ezininzi ze-GI, kubandakanya:

• isilonda
• isilungulela
• isicaphucaphu nokugabha
• ukopha
• krazula isisu, ithumbu elincinci, okanye amathumbu amakhulu
• urhudo
• ukuqhina
• iicampu
• imvakalelo yokugcwala
• ukudumba
• irhasi

Ubungozi obuphezulu kunye nezantsi be-GI kufuneka buthathelwe ingqalelo ngaphambi kokusebenzisa ibuprofen. I-Ibuprofen ukuba kukho umngcipheko we-GI esezantsi, nokuba iiproton pump inhibitor iyeza njengeNexium njengokukhusela.

Iziphumo ebezingalindelekanga ze-GI ziphezulu nge:

• abantu abangaphezu kweminyaka engama-65, njengamacala amane
• Imbali yokuchasana okanye ukubetha kwentliziyo
• Ukusetyenziswa kwe-corticosteroids, ii-anticoagulants ezinjenge-warfarin (Coumadin), i-serotonin reuptake inhibitors (SSRIs) ekhethiweyo njenge-sertraline (Zoloft), ii-antiplatelets ezifana ne-aspirin okanye i-clopidogrel (Plavix)
• isilonda peptic okanye ulcer ezinxulumene ulcer
• Ukusetyenziswa kotywala, njengoko kunokucaphukisa isisu, kunye nokusebenzisa ibuprofen ngotywala kunokunyusa umngcipheko wokopha esiswini.

Kufuneka wenze ntoni ukuba sele uyithathile

Khumbula, amanye amayeza ayasebenzisana ne-ibuprofen kunye neemeko zempilo. Qiniseka ukuba uxoxa ngezona ndlela zintle zokunciphisa umngcipheko weengxaki ze-GI nogqirha wakho kuqala.

Ukuba ufumana iimpawu ezincinci zesisu, amayeza athile okukhusela anokunceda:

• I-antacid esekwe kwimagniziyam inokunceda ngeempawu ezibuthathaka zentliziyo okanye i-acid reflux. Gwema ukuthatha ii-antacids ezisekwe kwi-aluminium kunye ne-ibuprofen, njengoko ziphazamisa ukufunxwa kwe-ibuprofen.
• Iproton pump inhibitor efana ne-esomeprazole (Nexium) inokunceda nge-asidi ye-asidi. Qiniseka ukuba ujonga kwikhemesti yakho malunga naziphi na iziphumo ebezingalindelekanga okanye ukuhlangana kweziyobisi.

Isilumkiso: Musa ukuthatha iintlobo ezininzi zokunciphisa iasidi ngexesha elinye. Ukuba iimpawu zakho aziphucuki okanye ziba zimbi, thetha nogqirha wakho.

Yeyiphi indlela ebalaseleyo yokuthatha ibuprofen?

Eyona ndlela yokuthatha ibuprofen ixhomekeke kubudala bakho kunye nemingcipheko. bonisa ukuthatha ibuprofen ngesikhuseli esiswini esifana ne-PPI yindlela efanelekileyo yokuphepha izilonda zep peptic, ukuba uyithatha ngeedosi eziphezulu ixesha elide.

Ukuba uthatha ibuprofen yokuphelisa iintlungu okwexeshana kwaye awunabungozi, unokukwazi ukuyithatha kwisisu esingenalutho ukuze uphucule ngokukhawuleza. Umkhuseli oqukethe i-magnesium unokunceda ngokukhawuleza.

Nini ukubona ugqirha

Kubalulekile ukufuna unyango ngokukhawuleza ukuba:

• banezitulo zokulibala ezimnyama
• zihlanza igazi
• Unentlungu ebuhlungu esiswini
• ube nesicaphucaphu nokugabha okungapheliyo
• unegazi kumchamo wakho
• yintlungu esifubeni
• unengxaki ngokuphefumla

Tsalela umnxeba kwi-911 ngoko nangoko ukuba unamava:

• irhashalala
• ukudumba kobuso, ulwimi, umqala, okanye imilebe
• ubunzima bokuphefumla
• ukuvutha

Umgca wezantsi

Iziphumo ebezingalindelekanga zesisu zezona ngxaki zixhaphakileyo ezichazwe nge-ibuprofen. Kubalulekile ukuqonda iingxaki ezinzulu okanye ezinzima ze-GI, ezinjengokopha, kunokwenzeka ngaphandle kweempawu zesilumkiso.

Qiniseka ukuba uxoxa ngembali yakho yeengxaki ezinxulumene ne-GI kunye nomboneleli wakho wezempilo ngaphambi kokuba uthathe ibuprofen ngokwakho. Ukuba ukhulelwe, thetha nogqirha wakho ngaphambi kokuba uthathe ibuprofen.

Kwiimeko ezinqunyelweyo, ukukhawulezisa ukukhawuleza kweempawu zentlungu, ukuthatha ibuprofen kwisisu esingenanto kunokuba kulungile. I-antiacid ene-magnesium inokubonelela ngokhuseleko kunye nokunceda ukubonelela ngokukhawuleza.

Ukusetyenziswa kwexesha elide, kuyanceda ukuthatha umkhuseli ukunqanda iziphumo ebezingalindelekanga ze-GI. Ngamanye amaxesha, ugqirha wakho uya kukhetha unyango olwahlukileyo.