Ukuqonda iMetastatic Breast Cancer kwiColon

Umxholo

• Yintoni umhlaza webele wemastastatic?
• Iimpawu ze-metastasis kwi-colon
• Yintoni ebangela imastastasis?
• Ukuchonga i-metastasis kwikholoni
• Colonoscopy
• I-sigmoidoscopy eguqukayo
• I-CT colonoscopy
• Ukunyanga umhlaza webele we-metastatic
• Unyango ngamayeza
• Unyango lweHormone
• Unyango ekujoliswe kulo
• Ugqirha
• Unyango ngemitha
• Yintoni umbono wabantu abanesifo somhlaza webele?

Yintoni umhlaza webele wemastastatic?

Xa umhlaza wamabele usasazeka, okanye udibanisa umzimba, kwamanye amalungu omzimba, uhlala usiya kwenye okanye kwezi ndawo zilandelayo:

• amathambo
• imiphunga
• isibindi
• ingqondo

Kunqabile ukuba isasazeke kwikholoni.

Kancinci ngaphezulu kwe-12 kwabasetyhini abayi-100 baya kufumana umhlaza wamabele ebomini babo. Kwezi meko, uqikelelo lophando malunga neepesenti ezingama-20 ukuya kuma-30 ziya kuba yimastastatic.

Ukuba umhlaza usasazeka, unyango luya kugxila ekugcineni umgangatho wobomi kunye nokucothisa ukusasazeka kwesifo. Alukho unyango lomhlaza webele we-metastatic okwangoku, kodwa inkqubela phambili kwezonyango inceda abantu ukuba baphile ubomi obude.

Iimpawu ze-metastasis kwi-colon

Iimpawu ezinxulunyaniswa nomhlaza webele osasazeke kwikholoni kubandakanya:

• isicaphucaphu
• ukugabha
• ukuxinana
• intlungu
• urhudo
• utshintsho kwisitulo
• ukudumba
• ukudumba kwesisu
• Ukuphelelwa ngumdla wokutya

Ukuphononongwa kwamatyala anyangiweyo kwikliniki yaseMayo kwafumanisa ukuba iipesenti ezingama-26 zabasetyhini ababene-colon metastases bafumana ukuvaleka kwamathumbu.

Kubalulekile ukuba uqaphele ukuba kuphononongo, i-colon metastases yaphukile ukugquma ezinye iisayithi ezisibhozo, kubandakanya:

• isisu
• umqala
• amathumbu amancinci
• ingcambu

Ngamanye amagama, le pesenti igubungela ngaphezulu kunabafazi abane-metastasis kwikholoni.

Yintoni ebangela imastastasis?

Umhlaza wamabele uhlala uqala kwiiseli zobuhle, eziyidlala ezivelisa ubisi. Inokuqala kwakhona kwimibhobho ehambisa ubisi kwingono. Ukuba umhlaza uhlala kwezi ndawo, uthathwa ngokuba awungeni.

Ukuba iiseli zomhlaza webele ziyaqhekeka kwisisu sokuqala kwaye zihambe ngegazi okanye ngenkqubo ye-lymphatic ziye kwelinye ilungu lomzimba wakho, kubhekiswa kuwo njengomhlaza webele we-metastatic.

Xa iiseli zomhlaza wamabele zihamba ziye emiphungeni okanye emathanjeni kwaye zenze amathumba apho, ezi tumors zintsha zisenziwa ziiseli zomhlaza wamabele.

Ezi tumors okanye amaqela eeseli athathelwa ingqalelo njengomhlaza wamabele kwaye awuyena umhlaza wemiphunga okanye umhlaza wamathambo.

Phantse zonke iintlobo zomhlaza zinakho ukusasazeka naphi na emzimbeni. Okwangoku, uninzi lulandela iindlela ezithile kumalungu athile. Akuqondwa ngokupheleleyo ukuba kutheni le nto isenzeka.

Umhlaza webele ungasasazeka kwikholoni, kodwa akunakwenzeka njalo. Kuqhelekile nokuba isasazeke kwindlela yokwetyisa.

Xa oku kusenzeka, umhlaza ufumaneka rhoqo kwithishu ye-peritoneal ebeka isisu esiswini, isisu, okanye amathumbu amancinci endaweni yamathumbu amakhulu, kubandakanya ikholoni.

Uluhlu lwabantu abanomhlaza webele we-metastases lubonisa uluhlu lweendawo ezinomhlaza webele ezinokuthi zisasazeke kuqala.

Olu pho nonongo lubonisa uluhlu lweendawo ezine eziphezulu zomhlaza wesifuba ukusasazeka:

• kwithambo iipesenti ezingama-41.1 zexesha
• ukuya kwimiphunga ngama-22.4 epesenti yexesha
• kwisibindi iipesenti ezingama-7.3 zexesha
• kwingqondo 7.3 yeepesenti yexesha

Iicolast metastases ziqhelekile kangangokuba azenzi uluhlu.

Xa umhlaza webele usasazeka kwikholoni, uhlala usenza njenge-lobular carcinoma. Olu luhlobo lomhlaza oluvela kwi-lobes evelisa ubisi lwebele.

Ukuchonga i-metastasis kwikholoni

Ukuba ufumana naziphi na kwezi mpawu, ngakumbi ukuba ukhe wafumana isifo somhlaza wamabele, thetha nogqirha wakho.

Ugqirha wakho unoku-odola uvavanyo olunye okanye nangaphezulu ukumisela ukuba umhlaza usasazekile na kwikholoni yakho.

Xa uvavanya ikholoni yakho, ugqirha wakho uya kujonga iipolyps. Iipolyps ukukhula okuncinci kwezihlunu ezingaqhelekanga ezinokuthi zenze ikholoni. Nangona uninzi lwazo lungenabungozi, iipolyps zinokuba ngumhlaza.

Xa une-colonoscopy okanye i-sigmoidoscopy, ugqirha wakho uya kususa naziphi na iipolyps abazifumanayo. Ezi polyps ziya kuthi emva koko kuvavanyelwe umhlaza.

Ukuba kufunyenwe umhlaza, olu vavanyo luya kubonisa ukuba ngaba umhlaza ngumhlaza webele osasazeke kwikholon okanye ukuba ngumhlaza omtsha ovela kwikholoni.

Colonoscopy

I-colonoscopy luvavanyo oluvumela ugqirha wakho ukuba ajonge ngaphakathi kwithumbu lakho elikhulu, elibandakanya i-rectum kunye nekholoni.

Basebenzisa ityhubhu ecekeceke, eguqukayo enekhamera encinci ekugqibeleni ebizwa ngokuba yi-colonoscope. Le ityhubhu ifakwe kwi-anus yakho kwaye inyuke ngekholoni yakho. I-colonoscopy inceda ugqirha wakho ukuba afumane:

• izilonda
• iipolyps
• amathumba
• ukudumba
• iindawo ezophayo

Ikhamera emva koko ithumela imifanekiso kwiscreen sevidiyo, esiya kuthi senze ukuba ugqirha wakho enze uxilongo. Ngokwesiqhelo, uya kunikwa amayeza okukunceda ulale uviwo.

I-sigmoidoscopy eguqukayo

I-sigmoidoscopy eguqukayo iyafana ne-colonoscopy, kodwa ityhubhu yesigmoidoscopy imfutshane kune-colonoscope. Kuphela zii-rectum kunye nenxalenye esezantsi yekholoni evavanyiweyo.

Amayeza ahlala engafuneki koluviwo.

I-CT colonoscopy

Ngamanye amaxesha ibizwa ngokuba yi-colonoscopy ebonakalayo, i-CT colonoscopy isebenzisa itekhnoloji ye-X-ray ephucukileyo ukuthatha imifanekiso emi-mbini yekolon yakho. Le yinkqubo engenazintlungu, engangenisiyo.

Ukunyanga umhlaza webele we-metastatic

Ukuba ufumana ukuxilongwa komhlaza webele osasazeke kwikholoni yakho, ugqirha wakho uya kuthi aodole iimvavanyo ezongezelelweyo ukuze abone ukuba umhlaza usasazekile na kwamanye amalungu omzimba wakho.

Nje ukuba wazi kakuhle ukuba kuqhubeka ntoni, wena nogqirha wakho ninokuthetha ngezona ndlela zonyango zilungileyo. Oku kunokubandakanya enye okanye ezingaphezulu kwezi zonyango zilandelayo.

Unyango ngamayeza

Amachiza e-Chemotherapy abulala iiseli, ngakumbi iiseli zomhlaza, ezahlulayo zivelise ngokukhawuleza. Iziphumo eziqhelekileyo zechemotherapy zibandakanya:

• ukulahleka kweenwele
• izilonda emlonyeni
• ukudinwa
• isicaphucaphu
• ukugabha
• ukwanda kwengozi yosulelo

Wonke umntu uphendula ngokwahlukileyo kwi-chemotherapy. Kwabaninzi, iziphumo ebezingalindelekanga zekhemotherapy zinokulawulwa kakhulu.

Unyango lweHormone

Uninzi lomhlaza webele osele kwi-colon yi-estrogen receptor-positive. Oku kuthetha ukuba ukukhula kweeseli zomhlaza wamabele kubangelwa ubuncinci kwinxalenye yihomoni estrogen.

Unyango lweHormone lunciphisa inani le-estrogen emzimbeni okanye luthintele i-estrogen ekubambeni kwiiseli zomhlaza wamabele kunye nokukhuthaza ukukhula kwazo.

Unyango lweHormone luhlala lusetyenziselwa ukunciphisa ukusasazeka ngakumbi kweeseli zomhlaza emva konyango lokuqala kunye nechemotherapy, utyando, okanye imitha.

Iziphumo ebezingalindelekanga ezibi kakhulu ezinokubakho ngabantu kunye nekhemotherapy kunqabile ukuba zenzeke ngonyango lwehomoni. Iziphumo zonyango lwehomoni zinokubandakanya:

• ukudinwa
• ukuphuthelwa
• kushushu
• ukoma kwilungu lobufazi
• utshintsho lweemvakalelo
• amahlwili egazi
• ukuncipha kwethambo kwabasetyhini abangaphambi kokuyeka ukuya exesheni
• ukwanda komngcipheko wesifo somhlaza wesibeleko kubafazi abasemva kwemini

Unyango ekujoliswe kulo

Unyango ekujoliswe kulo, oluhlala lubizwa ngokuba lonyango lweemolekyuli, lusebenzisa iziyobisi ezithintela ukukhula kweeseli zomhlaza.

Ngokwesiqhelo kuneziphumo ebezingalindelekanga ezimbalwa kunechemotherapy, kodwa iziphumo ebezingalindelekanga zinokubandakanya:

• irhashalala kunye nezinye iingxaki zolusu
• igazi elonyukayo
• ukugruzuka
• ukopha

Amanye amachiza asetyenziselwa unyango ekujoliswe kulo angonakalisa intliziyo, aphazamise amajoni omzimba, okanye enze umonakalo omkhulu kumalungu omzimba. Ugqirha wakho uya kukujonga ukuze uphephe naziphi na iingxaki.

Ugqirha

Ugqirha lunokwenziwa ukuze kususwe isithintelo samathumbu okanye iinxalenye zekolon ezinomhlaza.

Unyango ngemitha

Ukuba ukopha emathunjini, unyango lwemitha lunokuyinyanga. Unyango lwe-radiation lusebenzisa i-X-ray, imitha ye-gamma, okanye amasuntswana ahlawulisiweyo ukunciphisa amathumba kunye nokubulala iiseli zomhlaza. Iziphumo ezinokubandakanya:

• utshintsho lolusu kwindawo yemitha
• isicaphucaphu
• urhudo
• ukwanda komchamo
• ukudinwa

Yintoni umbono wabantu abanesifo somhlaza webele?

Nangona umhlaza osasazwayo ungenakuphiliswa, ukuqhubela phambili kunyango kunceda abantu abanomhlaza webele we-metastatic bakhokele ubomi obude.

Le nkqubela phambili ikwaphucula umgangatho wobomi kubantu abaphila nesi sifo.

Ngokwe-American Cancer Society, abantu abanomdlavuza webele we-metastatic banamathuba angama-27 okuphila ubuncinane iminyaka emihlanu emva kokuxilongwa.

Kubalulekile ukukhumbula ukuba lo ngumfanekiso oqhelekileyo. Ayiphenduli ngeemeko zakho ezizodwa.

Ugqirha wakho unokukunika eyona mbono ichanekileyo esekwe kwisifo sakho, imbali yezonyango, kunye nesicwangciso sonyango.