Umbhali: Virginia Floyd
Umhla Wokudalwa: 6 Eyethupha 2021
Hlaziya Umhla: 17 Eyenkanga 2024
Anonim
Terbinafine - An allyl amine antifungal agent | Mechanism and uses
Ividiyo: Terbinafine - An allyl amine antifungal agent | Mechanism and uses

Umxholo

Iigranules ze-Terbinafine zisetyenziselwa ukunyanga usulelo lomngundo entlonzeni. Amacwecwe e-Terbinafine asetyenziselwa ukunyanga usulelo lokungunda lweenzwane neenzipho. I-Terbinafine ikudidi lwamayeza abizwa ngokuba zii-antifungals. Isebenza ngokumisa ukukhula kokungunda.

I-Terbinafine iza njengama-granules nanjengecwecwe lokuthatha ngomlomo. Iigranule ze-Terbinafine zihlala zithathwa kunye nokutya okuthambileyo kube kanye ngemini kangangeeveki ezi-6. Iipilisi zeTerbinafine zihlala zithathwa kunye okanye ngaphandle kokutya kanye ngemini iiveki ezi-6 zosulelo lweenzipho kwaye kube kanye ngemini iiveki ezili-12 zosulelo lwezinzipho. Landela izikhokelo kwileyibhile yakho yonyango ngononophelo, kwaye ubuze ugqirha wakho okanye usokhemesti ukuba achaze nayiphi na indawo ongayiqondiyo. Thatha i-terbinafine ngokuchanekileyo njengoko kuyalelwe. Musa ukuthatha ngaphezulu okanye ngaphantsi kwayo okanye uthathe rhoqo kunokuba umiselwe ngugqirha wakho.

Ukulungiselela idosi yegrableine ye-terbinafine, tshiza yonke ipakethi yegranu kwicephe lokutya okuthambileyo okufana nepudding okanye iitapile ezicujiweyo. Musa ukufefa iigrensi kukutya okuthambileyo okusekwe kwiziqhamo, njengeapilesauce. Ukuba ugqirha ukuxelele ukuba uthathe iipakethi ezi-2 ze-terbinafine granules, ungafafaza imixholo yeepakethi ezimbini ngecephe elinye, okanye ungafafaza ipakethi nganye kwityuwa elinokutya okuthambileyo.


Gwinya icephe le granules kunye nokutya okuthambileyo ngaphandle kokuhlafuna.

I-fungus yakho ayinakunyangeka kwaphela kude kube ziinyanga ezimbalwa emva kokuba ugqibile ukuthatha i-terbinafine. Kungenxa yokuba kuthatha ixesha ukuba isikhonkwane esisempilweni sikhule kuso.

Ugqirha wakho okanye usokhemesti uya kukunika uxwebhu lolwazi lwesigulana lomenzi (Isikhokelo seyeza) xa uqala unyango nge-terbinafine kwaye ngalo lonke ixesha ugcwalisa amayeza akho. Funda ulwazi ngononophelo kwaye ubuze ugqirha okanye usokhemesti ukuba unayo nayiphi na imibuzo. Ungandwendwela noLawulo lwezoKutya noLawulo lweziyobisi (FDA) iwebhusayithi (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukufumana isiKhokelo seyeza.

I-Terbinafine ngamanye amaxesha isetyenziselwa ukunyanga umqala (usulelo lokungunda kolusu olwenza irhashalala elibomvu kwiindawo ezahlukeneyo zomzimba) kunye ne-jock itch (usulelo lokungunda kolusu emqolo okanye ezimpundu). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Ngaphambi kokuthatha i-terbinafine,

  • xelela ugqirha wakho kunye nosokhemesti ukuba ngaba uxabana ne-terbinafine, nawaphi na amanye amayeza, okanye nasiphi na isithako esikwigrabile okanye iipilisi ze-terbinafine. Buza usokhemesti wakho okanye ujonge isiKhokelo seyeza ukuze ufumane uluhlu lwezithako.
  • xelela ugqirha wakho kunye nosokhemesti ukuba yeyiphi na amayeza kagqirha kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye neemveliso zamayeza owathathayo. Qiniseka ukuba ukhankanya nayiphi na kwezi zilandelayo: amiodarone (Cordarone, Nexterone, Pacerone); ii-beta blockers ezinje nge-atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), kunye nepropranolol (Hemangeol, Inderal LA, Innopran XL); i-caffeine (kwi-Excedrin, i-Fioricet, i-Fiorinal, nabanye); cimetidine (iTagamet); icyclosporine (Gengraf, Neoral, Sandimmune); dextromethorphan (Delsym, kwiMucinex DM, Promethazine DM, abanye); flecainide; i-fluconazole (iDiflucan); ketoconazole (Nizoral); uhlobo lwe-monoamine oxidase yohlobo B (MAO-B) inhibitors ezifana ne-rasagiline (Azilect), kunye ne-selegiline (Eldepryl, Emsam, Zelapar); ipropafenone (Rythmol); irifampin (Rifadin, Rimactane, eRifamate, Rifater); i-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo njenge citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), kunye ne-sertraline (Zoloft); I-tricyclic antidepressants (TCAs) ezinje nge-amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), kunye neTrimipiline). Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
  • xelela ugqirha wakho ukuba ukhe unesifo sesibindi. Ugqirha wakho uya kukuxelela ukuba ungathathi i-terbinafine.
  • xelela ugqirha wakho ukuba unayo okanye wakha wanayo intsholongwane ye-immunodeficiency virus (HIV), ufumene i-immunodeficiency syndrome (i-AIDS), amajoni omzimba abuthathaka, i-lupus (imeko apho amajoni omzimba ahlasela izicwili kunye namalungu amaninzi kubandakanya ulusu, amalungu, igazi, nezintso), okanye isifo sezintso.
  • xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa, okanye uncancisa. Ukuba ukhulelwe ngelixa uthatha i-terbinafine, tsalela ugqirha wakho. Musa ukuncancisa ngelixa uthatha i-terbinafine.
  • cwangcisa ukuthintela ukukhanya kwelanga ngokungeyomfuneko okanye ixesha elide kunye nelanga elingelolokwenyani (iibhedi zokususa okanye unyango lwe-UVA / B) kwaye unxibe iimpahla zokuzikhusela, iiglasi zelanga kunye nescreen selanga. I-Terbinafine inokwenza ulusu lwakho lubuthathaka kwilanga.

Ngaphandle kokuba ugqirha wakho akuxelele ngenye indlela, qhubeka nokutya okuqhelekileyo.


Ukuba uthatha iigranules ze-terbinafine kwaye uyaphoswa yidosi, thatha idosi ephosiweyo kwakamsinya nje emva kokuba uyikhumbule. Nangona kunjalo, ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yethamo eqhelekileyo. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

Ukuba uthatha iipilisi ze-terbinafine kwaye uyaphoswa yidosi, thatha idosi ephosiweyo ngokukhawuleza nje ukuba uyikhumbule. Nangona kunjalo, ukuba idosi yakho elandelayo ingaphantsi kweeyure ezingama-4, tsiba idosi ephosiweyo kwaye uqhubeke neshedyuli yakho yesiqhelo yedosi. Sukuthatha idosi ephindwe kabini ukwenza eyilahlekileyo.

I-Terbinafine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

  • urhudo
  • ukuqunjelwa
  • ukurhawuzelela
  • intloko ebuhlungu
  • Ndiziva ndibuhlungu, ndingaxabisekanga, ndingenasiphelo, okanye ezinye iinguqu kwiimvakalelo
  • Ukuphelelwa ngamandla okanye umdla kwimisebenzi yemihla ngemihla
  • utshintsho kwindlela olala ngayo

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ezi mpawu zilandelayo aziqhelekanga; Nangona kunjalo, ukuba ufumana elinye lazo, tsalela ugqirha ngokukhawuleza okanye ufumane unyango olungxamisekileyo:

  • isicaphucaphu
  • Ukuphelelwa ngumdla wokutya
  • ukudinwa kakhulu
  • ukugabha
  • iintlungu kwindawo ephezulu yesisu
  • umchamo omnyama
  • izitulo ezimhlophe
  • mthubi ulusu okanye amehlo
  • irhashalala enkulu yolusu eqhubeka isiba mandundu
  • umkhuhlane, umqala obuhlungu, kunye neminye imiqondiso yosulelo
  • ukudumba kobuso, umqala, ulwimi, imilebe namehlo
  • ubunzima bokuginya okanye ukuphefumla
  • ukudinwa
  • amadlala e-lymph adumbileyo
  • ukuxobuka, ukudubula, okanye ukuchitha ulusu
  • urhwebo
  • ukurhawuzelela
  • irhashalala ebomvu okanye enamaxolo enokuthi ithande ukukhanya kwelanga
  • ukulahleka kwebala lolusu
  • izilonda zomlomo
  • umqala obuhlungu, umkhuhlane, ukubanda, kunye neminye imiqondiso yosulelo
  • iintlungu zesifuba
  • ukopha okungachazwanga okanye ukugruzuka
  • igazi kumchamo
  • ukukhawuleza kwentliziyo okanye okungaqhelekanga

Kuya kufuneka uyazi ukuba i-terbinafine inokubangela ilahleko okanye utshintsho kwindlela ongcamla ngayo okanye yevumba. Ukuphulukana nokungcamla kunokubangela ukuncipha kokutya, ukunciphisa umzimba, kunye noxinzelelo okanye iimvakalelo zokudakumba. Olu tshintsho lunokuphuculwa kungekudala emva kokuyeka unyango nge-terbinafine inokuhlala ixesha elide, okanye inokuba sisisigxina. Ukuba uqaphela ilahleko okanye umahluko kwindlela ongcamla okanye yevumba ngayo, tsalela ugqirha wakho.


I-Terbinafine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Gcina eli yeza kwisikhongozeli lifikile, livalekile, kwaye alifumaneki ebantwaneni. Yigcine kubushushu begumbi kwaye kude nobushushu obuninzi kunye nokufuma (hayi kwigumbi lokuhlambela). Gcina iipilisi ze-terbinafine kude nokukhanya.

Kubalulekile ukugcina onke amayeza ngaphandle kwamehlo kunye nokufikelela kwabantwana njengezikhongozeli ezininzi (ezinje ngeeveki zeepilisi zeveki kunye nezo zamehlo, iikhrim, iipatches, kunye ne-inhalers) azinyangeki kwaye abantwana abancinci banokuzivula ngokulula. Ukukhusela abantwana abancinci kwiityhefu, soloko ukhiya iminqwazi yokhuseleko kwaye ubeke amayeza kwindawo ekhuselekileyo-leyo iphakame kwaye iphakame kwaye ingabonakali kubo kwaye ifikelele kuyo. http://www.upandaway.org

Amayeza angafunekiyo kufuneka achithwe ngeendlela ezizodwa zokuqinisekisa ukuba izilwanyana zasekhaya, abantwana kunye nabanye abantu abanakuzisebenzisa. Nangona kunjalo, akufuneki uligungxule eli yeza kwindlu yangasese. Endaweni yoko, eyona ndlela yokulahla amayeza akho yinkqubo yokubuyisa amayeza. Thetha kumayeza wakho okanye unxibelelane nesebe lakho lenkunkuma / lokurisayikilisha ukuze ufunde malunga neenkqubo zokubuyisa kwindawo ohlala kuyo. Jonga i-FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) ngolwazi oluthe kratya ukuba awunakho ukufikelela kwinkqubo yokubuyisa.

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu libanda kungaquka oku kulandelayo:

  • isicaphucaphu
  • ukugabha
  • isisu esibuhlungu
  • isiyezi
  • irhashalala
  • ukuchama rhoqo
  • intloko ebuhlungu

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuku-odola iimvavanyo ezithile zelebhu ngaphambi kokuba uqale unyango kunye nonyango lwakho.

Musa ukuvumela nabani na ukuba athathe amayeza akho. Buza usokhemesti wakho nayiphi na imibuzo onayo malunga nokuzalisa amayeza akho.

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

  • ILamisil®
Ukuhlaziywa kokugqibela-01/15/2018

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