IPyrimethamine (iDaraprim)

Umxholo

• Ixabiso
• Iimpawu
• Kusetyenziswa kwanjani
• Imiphumela
• Ukungqinelana

I-Daraprim liyeza elisebenzisa i-antimalarial elisebenzisa i-pyrimethamine njengesithako esisebenzayo, esikwaziyo ukuthintela ukuveliswa kwee-enzymes yi-protozoan ejongene nesifo seengcongconi, ngaloo ndlela inyanga isifo.

I-Daraprim inokuthengwa kwiikhemesti eziqhelekileyo ngugqirha ngohlobo lweebhokisi ezineepilisi ezili-100 ze-25 mg.

Ixabiso

Ixabiso leDaraprim limalunga ne-7 reais, nangona kunjalo inani linokwahluka ngokwendawo ethengwe kuyo ichiza.

Iimpawu

I-Daraprim ibonakalisiwe kuthintelo kunye nonyango lwe-malaria, kunye namanye amayeza. Ukongeza, iDaraprim inokusetyenziselwa ukunyanga iToxoplasmosis, ngokokubonisa kukagqirha.

Kusetyenziswa kwanjani

Indlela yokusebenzisa iDaraprim iyahluka ngokwenjongo yonyango kunye nobudala besigulana, kunye nezikhokelo ngokubanzi kubandakanya:

Uthintelo lweMalariya

• Abantu abadala nabantwana ngaphezulu kweminyaka eli-10: 1 icwecwe ngeveki;
• Abantwana abaneminyaka emi-5 ukuya kweli-10 ubudala: ½ Ithebhulethi ngeveki;
• Abantwana abangaphantsi kweminyaka emi-5: Ithebhulethi ngeveki.

Unyango lwe-Malaria

• Abantu abadala nabantwana ngaphezulu kweminyaka eli-14: Iipilisi ezi-2 ukuya kwezi-3 kunye ne-1000 mg ukuya kwi-1500 mg ye-sulfadiazine kwidosi enye;
• Abantwana abaneminyaka eli-9 ukuya kweli-14 ubudala: Amacwecwe ama-2 kunye ne-1000 mg ye-sulfadiazine kwidosi enye;
• Abantwana abaneminyaka emi-4 ukuya kweli-8 ubudala: Ithebhulethi enye kunye ne-1000 mg ye-sulfadiazine kwidosi enye;
• Abantwana abangaphantsi kweminyaka emi-4: Ithebhulethi kunye ne-1000 mg yesulfadiazine kwidosi enye.

Imiphumela

Iziphumo ebezingalindelekanga eziphambili zeDaraprim zibandakanya ukwaliwa sisikhumba, ukubetha kwentliziyo, isicaphucaphu, iicramps, urhudo, ukungabi namdla wokutya, igazi kumchamo kunye notshintsho kuvavanyo lwegazi.

Ukungqinelana

I-Daraprim iyaphikiswa kwizigulana ezine-anemia ye-megaloblastic yesibini ngenxa yokusilela kwe-folate okanye i-hypersensitivity to pyrimethamine okanye naliphi na icandelo lefomula.