I-Prednisolone: ​​yeyantoni, iziphumo ebezingalindelekanga kunye nendlela yokuthatha

Umxholo

• Yenzelwe ntoni
• Indlela yokuthatha
• 1. 5 okanye 20 mg iipilisi
• 2. 3 mg / ml okanye isiraphu eyi-1 mg / ml
• 3. 11 mg / mL isisombululo sokulahla
• Imiphumela
• Ukungqinelana
• Yintoni umahluko phakathi kwe-prednisolone kunye ne-prednisone?

I-Prednisolone yi-steroidal anti-inflammatory, eboniswe kunyango lweengxaki ezinje nge-rheumatism, utshintsho kwihomoni, i-collagen, i-allergies kunye neengxaki zolusu kunye neliso, ukudumba ngokubanzi, ukuphazamiseka kwegazi kunye neengxaki, ukuphefumla, isisu kunye neengxaki zemithambo-luvo kunye nosulelo. Ukongeza, esi sixhobo singasetyenziswa kunyango lomhlaza.

Eli yeza lifumaneka ngohlobo lweepilisi, ukunqunyanyiswa ngomlomo okanye ukuhla kwaye zingathengwa ezikhemesti xa kuboniswa amayeza.

Yenzelwe ntoni

I-Prednisolone sisiyobisi esisebenza njenge-anti-inflammatory kunye ne-immunosuppressant, eboniswa kunyango lwezifo apho iinkqubo zokuvuvukala kunye nokuzimela, unyango lweengxaki ze-endocrine kunye nokunxulunyaniswa namanye amayeza onyango lomhlaza. Yiyo loo nto i-prednisolone iboniswa kwezi meko zilandelayo:

• Iingxaki ze-Endocrine, njengokusilela kwe-adrenocortical, i-hyperplasia ye-adrenal ye-congenital, i-thyroiditis enganyangekiyo kunye ne-hypercalcemia ehambelana nomhlaza;
• Rheumatism, ezifana ne-psoriatic okanye i-rheumatoid arthritis, i-ankylosing spondylitis, i-bursitis, i-tenosynovitis engacacanga, isifo se-arthritis esibuhlungu, i-post-traumatic osteoarthritis, i-osteoarthritic synovitis kunye ne-epicondylitis;
• Collagenoses, ngakumbi iimeko zenkqubo ye-lupus erythematosus kunye ne-rheumatic carditis ebukhali;
• Izifo zolusuNjengoko pemphigus, ezinye dermatitis, mycosis kunye ukhwekhwe kakhulu;
• Umzimba, ezifana ne-rhinitis ye-allergen, unxibelelwano kunye ne-atopic dermatitis, izifo ze-serum kunye nokusabela kwe-hypersensitivity kwiziyobisi;
• Izifo zamehlo, ezinjengezilonda ze-corneal marginal marginal, i-ophthalmic herpes zoster, ukudumba kwecandelo elingaphandle, ukusasazeka kwe-choroiditis kunye ne-posterior uveitis, u-ophthalmia onovelwano, isifo se-conjunctivitis, i-keratitis, i-chorioretinitis, i-optic neuritis, i-iritis kunye ne-iridocyclitis;
• Izifo zokuphefumla, ezinje ngeempawu zesarcoidosis, iLöefler's syndrome, i-berylliosis, ezinye iimeko zesifo sephepha, i-aspiration pneumonitis kunye ne-asthma ye-bronchial;
• Ukuphazamiseka kwegazi, ezinjenge-idiopathic thrombocytopenic purpura kunye ne-thrombocytopenia yesibini kubantu abadala, bafumana i-hemolytic anemia, erythrocytic anemia kunye ne-erythroid anemia;
• Umhlaza, kunyango lwe-leukemias kunye ne-lymphomas.

Ukongeza, i-prednisolone inokusetyenziselwa ukunyanga ukuqaqamba kwesifo sokuqina kwamathambo, ukunciphisa ukudumba kwimeko ye-idiopathic nephrotic syndrome kunye ne-lupus erythematosus kunye nokugcina isigulana esine-ulcerative colitis okanye i-enteritis yommandla.

Indlela yokuthatha

Idosi ye-prednisolone yahluka kakhulu ngokobunzima, ubudala, isifo esiza kunyangwa kunye nefom yamayeza kwaye kufuneka ihlale imiselwe ngugqirha.

1. 5 okanye 20 mg iipilisi

• Abantu abadala: idosi yokuqala yahluka ukusuka kwi-5 ukuya kwi-60 mg ngosuku, elingana ne-1 5 mg yecwecwe okanye iipilisi ze-3 20 mg.
• Abantwana: idosi yokuqala yahluka ukusuka kwi-5 ukuya kwi-20 mg ngosuku, elingana ne-1 5 mg yecwecwe okanye ithebhulethi ye-1 20 mg.

Umthamo kufuneka uncitshiswe kancinci xa ichiza lilawulwa ngaphezulu kweentsuku ezimbalwa. Iipilisi kufuneka ziginywe ziphele, kunye neglasi yamanzi, ngaphandle kokophula okanye ukuhlafuna.

2. 3 mg / ml okanye isiraphu eyi-1 mg / ml

• Abantu abadalaImilinganiselo yethamo elicetyiswayo ukusuka kwi-5 ukuya kwi-60 mg ngosuku;
• Iintsana naBantwana: idosi ekhuthazwayo iyahluka ukusuka kwi-0.14 ukuya kwi-2 mg nganye kwi-1 kg yesisindo somntwana ngosuku, yahlulwe yaya ku-3 ukuya ku-4 kulawulo lwemihla ngemihla;

Umthamo oza kulinganiswa uxhomekeke kuxinzelelo lwesisombululo somlomo, njengoko kukho iingcaciso ezimbini ezahlukeneyo. Umthamo kufuneka uncitshiswe kancinci xa ichiza lilawulwa ngaphezulu kweentsuku ezimbalwa.

3. 11 mg / mL isisombululo sokulahla

• Abantu abadalaImilinganiselo yethamo elicetyiswayo ukusuka kwi-5 ukuya kwi-60 mg ngosuku, elingana namaconsi e-9 okanye i-109 yehla ngemini.
• Abantwana: idosi ekhuthazwayo iyahluka ukusuka kwi-0.14 ukuya kwi-2 mg nganye kwi-1 kg yesisindo somntwana, ilawulwa amaxesha ama-1 ukuya kwezi-4 ngosuku.

Ithontsi ngalinye lilingana ne-0.55 mg ye-prednisolone. Umthamo kufuneka uncitshiswe kancinci xa ichiza lilawulwa ngaphezulu kweentsuku ezimbalwa.

Idosi ekhuthazwayo kunye nexesha lokunyanga nge-Prednisolone kufuneka iboniswe ngugqirha, kuba ezi zixhomekeke kwingxaki eza kunyangwa, ubudala kunye nempendulo yesigulana kunyango.

Imiphumela

Iziphumo eziqhelekileyo ezinokuthi zenzeke ngexesha lonyango kunye ne-prednisolone yonyusa umdla wokutya, ukugaya ukutya okungalunganga, i-peptic ulcer, i-pancreatitis kunye ne-ulcerative esophagitis, uvalo, ukudinwa kunye nokungalali.

Ukongeza, ukungahambelani komzimba, ukuphazamiseka kwamehlo, njenge-cataract, i-glaucoma, i-exophthalmos kunye nokuqina kosulelo lwesibini ziifungi okanye intsholongwane yamehlo, ukunciphisa ukunyamezelana kwee-carbohydrate, ukubonakaliswa kwesifo seswekile esifihlakeleyo kunye nesidingo esonyukayo se-insulin okanye iiarhente zomlomo ze-hypoglycemic. abaneswekile.

Unyango olunedosi eziphezulu ze-corticosteroids lunokubangela ukonyuka okuphawuleka kwi-triglycerides egazini.

Bona ngakumbi malunga neziphumo ebezingalindelekanga zecorticosteroids.

Ukungqinelana

I-Prednisolone iyaphikiswa kubantu abane-fungic system okanye izifo ezingalawulwayo kunye nezigulana ezinesifo se-prednisolone okanye naliphi na icandelo lefomula.

Ukongeza, eli yeza akufuneki lisetyenziswe ngabafazi abakhulelweyo okanye abancancisayo, ngaphandle kokuba kucetyiswa ngugqirha.

Yintoni umahluko phakathi kwe-prednisolone kunye ne-prednisone?

I-Prednisone yiprodrug ye-prednisolone, oko kukuthi, i-prednisone yinto engasebenziyo, ukuze isebenze kufuneka iguqulwe esibindini ibe yi-prednisolone, ukuze isebenze.

Ke, ukuba umntu uginya i-prednisone okanye i-prednisolone, isenzo esenziwe sisiyobisi siya kuba sinye, kuba i-prednisone iguqulwa yasebenza, esibindini, yaba yi-prednisolone. Ngesi sizathu, i-prednisolone inezibonelelo ezininzi kubantu abaneengxaki zesibindi, njengoko ingadingi kuguqulwa esibindini ukuze basebenzise umzimba.