Iipurura

Umxholo

• Imifanekiso yepurura
• Yintoni ebangela ipurura?
• I-purpura ichongwa njani?
• Iphathwa njani ipurura?
• ICorticosteroids
• I-immunoglobulin efakwa ngaphakathi
• Olunye unyango lweziyobisi
• Splenectomy
• Yintoni umbono we-purpura?
• Ukuhlala ne-purpura
• Q:
• A:

Yintoni ipurura?

I-Purpura, ekwabizwa ngokuba ngamabala egazi okanye ukopha kolusu, kubhekisa kumabala anombala omfusa aziwa kakhulu kulusu. Amabala anokuvela nakwizitho okanye inwebu yangaphakathi, kubandakanya inwebu engaphakathi emlonyeni.

I-Purpura yenzeka xa imithambo yegazi encinci iqhuma, ibangela igazi ukuba lidade phantsi kolusu. Oku kunokwenza amabala amfusa kulusu oluhluka ngokobungakanani ukusuka kumachaphaza amancinci ukuya kwiimpawu ezinkulu. Amabala e-Purpura ahlala enobungozi, kodwa anokubonisa imeko enzulu yonyango, njengokuphazamiseka kwegazi.

Ngamanye amaxesha, amanqanaba asezantsi eplatelet kunokubangela ukutyumka okugqithisileyo kunye nokopha. Iiplatelets ziiseli ezikunceda kwigazi lakho. Amanqanaba asezantsi eplatelet angazuzwa njengelifa okanye ufuzo, kodwa zinokunxulumana nezangoku:

• Ukunyuka komongo wethambo
• umhlaza
• ichemotherapy
• Ukutshintsha kweseli
• Usulelo lwe-HIV
• ukutshintshwa kwehomoni
• Unyango lwe-estrogen
• ukusetyenziswa kwamayeza athile

Kuya kufuneka usoloko uqhagamshelana nogqirha wakho ukuba uthe waphawula nakuphi na ukukhula kunye notshintsho kulusu lwakho.

Imifanekiso yepurura

Yintoni ebangela ipurura?

Zimbini iintlobo zepurura: i-nonthrombocytopenic kunye ne-thrombocytopenic. I-nonthrombocytopenic kuthetha ukuba unamanqanaba esiqhelo egazi egazini lakho. I-Thrombocytopenic ithetha ukuba unexabiso eliphantsi kuneplatelet.

Oku kulandelayo kunokubangela i-nonthrombocytopenic purpura:

• ukuphazamiseka okuchaphazela ukujiya kwegazi
• iingxaki ezithile zokuzalwa, ezikhoyo okanye ngaphambi kokuzalwa, ezinje nge-telangiectasia (ulusu olubuthathaka kunye nezicubu ezinxibelelanayo) okanye i-Ehlers-Danlos syndrome
• amayeza athile, kubandakanya i-steroids kunye nezo zichaphazela ukusebenza kweplatelet
• imithambo yegazi ebuthathaka
• ukudumba kwimithambo yegazi
• iscurvy, okanye ukuswela kakhulu ivithamin C

Oku kulandelayo kunokubangela i-thrombocytopenic purpura:

• amayeza athintela iiplatelets ekubeni zenze okanye ziphazamise ucoceko oluqhelekileyo
• iziyobisi ezibangela ukuba umzimba uqalise ukungaziphenduli komzimba ngokuchasene neeplatelets
• utofelo-gazi kutshanje
• ukuphazamiseka komzimba njenge-idiopathic thrombocytopenic purpura
• usulelo egazini
• Usulelo lwe-HIV okanye i-Hepatitis C, okanye ezinye izifo zentsholongwane (Epstein-Barr, rubella, cytomegalovirus)
• Umkhuhlane obonwe yiNtaba yeRocky (ukusuka kulunywe likhalane)
• Inkqubo ye lupus erythematous

I-purpura ichongwa njani?

Ugqirha wakho uya kuvavanya ulusu lwakho ukufumanisa i-purpura. Banokubuza malunga nosapho kunye nembali yempilo yakho, njengaxa kwaqala ukuvela amabala. Ugqirha wakho unokwenza i-biopsy yolusu ukongeza kuvavanyo lwegazi kunye neplatelet.

Ezi mvavanyo ziya kunceda ukuvavanya ukuba ingaba i-purpura yakho sisiphumo seemeko ezibi kakhulu, njengeplatelet okanye ukuphazamiseka kwegazi. Amanqanaba eeplatelet anokunceda ekuchongeni unobangela wepurura kwaye uya kunceda ugqirha wakho amisele eyona ndlela ilungileyo yonyango.

I-Purpura inokuchaphazela abantwana kunye nabantu abadala. Abantwana banokuyiphuhlisa emva kokosuleleka yintsholongwane kwaye banokuchacha ngokupheleleyo ngaphandle kongenelelo. Uninzi lwabantwana abane-thrombocytopenic purpura bachacha ngokupheleleyo kwiinyanga ezimbalwa zokuqala kwesi sifo. Nangona kunjalo, kubantu abadala, oonobangela be-purpura bahlala benganyangeki kwaye bafuna unyango ukunceda ukulawula iimpawu kunye nokugcina ukubalwa kweplatelet ngaphakathi kuluhlu olusempilweni.

Iphathwa njani ipurura?

Uhlobo lonyango oza kukuyalela ugqirha luxhomekeka kwisizathu se-purpura yakho. Abantu abadala abafunyaniswa benesifo se-thrombocytopenic purpura sinokuphola ngaphandle kongenelelo.

Uya kudinga unyango ukuba ukuphazamiseka okubangela i-purpura kungahambi ngokwakho. Unyango lubandakanya amayeza kwaye ngamanye amaxesha i-splenectomy, okanye utyando lokususa udakada. Unokucelwa ukuba uyeke ukuthatha amayeza aphazamisa ukusebenza kweplatelet, njenge-aspirin, i-blood thinner kunye ne-ibuprofen.

ICorticosteroids

Ugqirha wakho unokukuqala ngamayeza e-corticosteroid, anokunceda ekunyuseni inani leplatelet yakho ngokunciphisa ukusebenza kwamajoni akho omzimba. Ihlala ithatha malunga neeveki ezimbini ukuya kwezintandathu ukubala kweplatelet yakho ukubuyela kwinqanaba elikhuselekileyo. Xa kunjalo, ugqirha wakho uya kuyeka iyeza.

Kubalulekile ukuba uthethe nogqirha wakho malunga nemingcipheko yokuthatha i-corticosteroids ixesha elide. Ukwenza njalo kunokubangela iziphumo ebezingalindelekanga ezimandundu, ezinje ngokufumana ubunzima, ukungaboni ngamehlo, kunye nethambo.

I-immunoglobulin efakwa ngaphakathi

Ukuba uhlobo lwakho lwe-purpura lubangela ukopha kakhulu, ugqirha wakho angakunika iyeza elifakwa ngaphakathi elibizwa ngokuba yi-intravenous immunoglobulin (IVIG). Banokukunika i-IVIG ukuba ufuna ukwandisa ukubala kweplatelet yakho ngokukhawuleza ngaphambi kotyando. Olu nyango luhlala lusebenza ekonyuseni ubalo lweplatelet yakho, kodwa isiphumo sihlala sisebenza kwixesha elifutshane kuphela. Inokubangela iziphumo ebezingalindelekanga ezinje ngentloko, isicaphucaphu, kunye nefiva.

Olunye unyango lweziyobisi

Amachiza amatsha asetyenziselwa ukunyanga inani eliphantsi leplatelet kubantu abane-immune engapheliyo (idiopathic) thrombocytopenic purpura (ITP) yi-romiplostim (Nplate) kunye ne-eltrombopag (Promacta). La mayeza abangela ukuba umongo wethambo uvelise iiplatelet ezingaphezulu, ezinciphisa umngcipheko wokugruzuka nokopha. Iziphumo ezinokubakho zibandakanya:

• intloko ebuhlungu
• isiyezi
• isicaphucaphu
• intlungu edibeneyo okanye yemisipha
• ukugabha
• umngcipheko okhulayo wamahlwili egazi
• isifo esimandundu soxinzelelo lwamalungu okuphefumla
• ukukhulelwa

Unyango lwe-Biologic, olunje ngeziyobisi rituximad (Rituxan), lunokunceda ukunciphisa ukuphendula kwamajoni omzimba. Isetyenziselwa ukunyanga abaguli abane-thrombocytopenic purpura ebukhali kunye nezigulana unyango lwe-corticosteroid olungasebenzi. Iziphumo ezinokubandakanya:

• uxinzelelo lwegazi oluphantsi
• umqala obuhkungu
• irhashalala
• ifiva

Splenectomy

Ukuba amayeza awasebenzi kunyango lwe-thrombocytopenic purpura, ugqirha wakho. Ukususa udakada yindlela ekhawulezayo yokwandisa ubalo lweplatelet yakho. Kungenxa yokuba udakada yeyona ndawo iphambili inoxanduva lokususa iiplatelets.

Nangona kunjalo, i-splenectomies ayisebenzi kuwo wonke umntu. Olu tyando luza nemingcipheko, njengokunyuka komngcipheko wosulelo. Kwixesha likaxakeka, xa i-purpura ibangela ukopha kakhulu, izibhedlele ziya kutofelwa iiplatelet concentrate, i-corticosteroids kunye ne-immunoglobulin.

Nje ukuba unyango luqaliswe, ugqirha wakho uya kubeka esweni ukubalwa kweplatelet yakho ukunceda ukufumanisa ukuba ayisebenzi okanye ayisebenzi. Banokutshintsha unyango lwakho ngokuxhomekeke ekusebenzeni kwayo.

Yintoni umbono we-purpura?

Imbonakalo ye-purpura ixhomekeke kwimeko ebangela oko. Xa ugqirha wakho eqinisekisa ukuxilongwa, baya kuxoxa ngeendlela zokonyango kunye nembono yexesha elide ngemeko yakho.

Kwiimeko ezinqabileyo, i-thrombocytopenic purpura eshiywe inganyangwa inokubangela umntu ukuba aphume ukopha kakhulu kwinxalenye ethile yomzimba wakhe. Ukopha ngokugqithileyo kwingqondo kunokukhokelela ekubulaweni kwengqondo ebulalayo.

Abantu abaqala unyango kwangoko okanye abanesimo esibuhlungu bahlala befumana kwakhona. Nangona kunjalo, i-purpura inokuba sisifo esinganyangekiyo kwiimeko ezinzima okanye xa unyango lulibazisekile. Kuya kufuneka ubone ugqirha wakho ngokukhawuleza ukuba uyakrokrela ukuba une-purpura.

Ukuhlala ne-purpura

Ngamanye amaxesha amabala avela kwi-purpura awayi kuhamba ngokupheleleyo. Amayeza athile kunye nemisebenzi inokwenza la mabala abe mandundu. Ukunciphisa umngcipheko wokwenza amabala amatsha okanye ukwenza amabala abe mandundu, kuya kufuneka uphephe amayeza anciphisa ukubalwa kweplatelet. La mayeza aquka i-aspirin kunye ne-ibuprofen. Kuya kufuneka uphinde ukhethe imisebenzi enefuthe eliphantsi kwimisebenzi eneempembelelo eziphezulu. Izinto ezinempembelelo ephezulu zinokunyusa umngcipheko wokulimala, ukugruzuka kunye nokopha.

Kunokuba nzima ukumelana nemeko engapheliyo. Ukufikelela kunye nokuthetha nabanye abanesifo kunokunceda. Jonga kwi-intanethi ngamaqela enkxaso anokunxibelelana nabanye abane-purpura.

Q:

Ngaba lukhona unyango lwendalo okanye lweengcambu olusebenzayo kwi-purpura?

Isigulana esingaziwayo

A:

Ngenxa yokuba i-purpura ikhula kwizizathu ezahlukeneyo, akukho nyango "ilingana nayo yonke into". Kubalulekile ukufumanisa unobangela wengxaki. Okwangoku, akukho lunyango lwendalo okanye amayeza esintu anokuthenjwa ukulawula le meko.

Ukuba unomdla wokuphonononga unyango lwendalo okanye olunye unyango lokhathalelo lwempilo, kuhlala kulunge kakhulu ukudibana nogqirha ohlanganisayo. Aba ngoogqirha abaqeqeshwe ngokukodwa kumayeza esintu kunye nawokuncedisa. Ujoliso lwabo kwindlela yengqondo-yomzimba yokunyanga. Unokufumana iingcali ezifanelekileyo zokudibanisa impilo: http://integrativemedicine.arizona.edu/alumni.html

UJudi Marcin, iimpendulo ze-MDA zimele izimvo zeengcali zethu zonyango. Yonke imixholo inolwazi ngokungqongqo kwaye akufuneki ukuba ithathelwe ingqalelo njengengcebiso yezonyango.