IHemolytic Uremic Syndrome: yintoni, izizathu kunye nonyango

Umxholo

• Izizathu eziphambili
• Iimpawu zeHemolytic Uremic Syndrome
• Ukuchongwa kwe-HUS
• Unyango lwenziwa njani

I-Hemolytic Uremic Syndrome, okanye i-HUS, sisifo esibonakaliswa ziimpawu ezintathu eziphambili: i-hemolytic anemia, ukusilela kwezintso kunye ne-thrombocytopenia, ehambelana nokuhla kwenani leeplatelets egazini.

Esi sifo senzeka ngokulula ebantwaneni ngenxa yokutya okungcoliswe ziibhaktheriya ezinje nge-Escherichia coli, kodwa inokwenzeka nakubantu abadala ngenxa yosulelo kunye nangenxa yezinye iimeko, ezinje ngoxinzelelo lwegazi kunye nescleroderma, umzekelo.

Izizathu eziphambili

Oyena nobangela we-HUS, ngakumbi ebantwaneni, lusulelo ngu Escherichia coli, ISalmonella sp., okanye Shigella sp., Ezineentsholongwane ezinako ukukhupha ityhefu egazini kwaye zikhokelele ekwakhiweni kwetrombi encinci kwimithambo, ekhokelela ekutshatyalalisweni kweeseli ezibomvu zegazi kunye nokonakala kwezintso. Olu hlobo losulelo luhlala lusenzeka ngokusetyenziswa kokutya okungcoliswe zezi ntsholongwane, ke ngoko, kubalulekile ukuthathela ingqalelo ucoceko lomntu kunye nokutya. Qonda ukuba kunjani ucoceko lokutya.

Ngaphandle kokuxhaphaka kakhulu ebantwaneni, iHemolytic Uremic Syndrome nayo inokwenzeka kubantu abadala, enokubangelwa kukutya ukutya okungcoliswe ziibhaktiriya, kunye nokuba sisiphumo sezinye iimeko, ezinje ngokusilela kwezintso nasemva kokubeleka, iscleroderma, usulelo lwentsholongwane iHIV kunye i-antiphospholipid syndrome, umzekelo.

Iimpawu zeHemolytic Uremic Syndrome

Iimpawu zokuqala ze-HUS ziyafana nesisu, ifiva, ukugodola, urhudo, ukudinwa kakhulu, ukugabha nokuba buthathaka. Ngexesha lesi sifo, ezinye iimpawu zingavela, ezinje:

• Ukungaphumeleli kakuhle kwezintso;
• Umchamo omncinci;
• IJaundice;
• Ubukho begazi kumchamo kunye nelindle;
• IPallor;
• Inkangeleko yamabala amfusa eluswini;
• I-jaundice.

Nangona ingaqhelekanga, kusenokubakho ukubonakala kweempawu zemithambo-luvo, ezinjengokuxhuzula, ukuba nochuku, ukungabikho zingqondweni kunye nesiqa, umzekelo. Ukongeza, kubalulekile ukuba uqaphele ukuba ayizizo zonke iimeko ze-HUS ezandulelwa lurhudo, kwaye kubalulekile ukuba xa kukho naluphi na uphawu olucebisa isifo, umntu lowo uya kugqirha ayokwenza isifo kwaye aqale unyango, ukuthintela iingxaki ezifana nokusilela kwentliziyo, ukusilela okungapheliyo kwezintso.

Ukuchongwa kwe-HUS

Ukuchongwa kwe-HUS kwenziwa ngokuvavanywa kweempawu kunye neziphumo zovavanyo lwelabhoratri olucelwe ngugqirha, olujolise ekuchongeni ezona mpawu zintathu ziphambili zesi sifo, eziyi-hemolytic anemia, ukunciphisa ukubala kweplatelet kunye notshintsho ekusebenzeni kwezintso .

Ngenxa yoko, ugqirha uhlala ecela ukusebenza kokubalwa kwegazi, apho ukwanda kwenani leukocyte kungqinisisiwe, ukwehla kwenani leeplatelets, iiseli ezibomvu zegazi kunye nehemoglobin, kunye nobukho be-schizocytes, eziziingceba iiseli ezibomvu zegazi ezibonisa ukuba ezi seli zigqabhukile ngenxa yemeko ethile, edla ngokubakho kwe-thrombi. Funda indlela yokutolika ubalo lwegazi.

Iimvavanyo ezivavanya ukusebenza kwezintso, ezinje ngomlinganiso we-urea kunye ne-creatinine egazini, ziyacelwa, ezonyuswe kule meko. Ukongeza, kukho ukwanda kokuxinana kwe-bilirubin engathanga ngqo egazini kunye ne-LDH, edla ngokubonisa i-microangiopathic hemolysis, okt ukuba iiseli ezibomvu zegazi ziyatshatyalaliswa ngenxa yobukho be-thrombi encinci emithanjeni.

Ukongeza kwezi mvavanyo, ugqirha unokucela inkcubeko, ejolise ekuchongeni ibhaktiriya ejongene nosulelo, ukuba kunjalo, kwaye ke ichaze ukuba loluphi olona nyango lulungileyo lokunyanga i-HUS.

Unyango lwenziwa njani

Unyango lwe-Hemolytic Uremic Syndrome lwenziwa ukunciphisa iimpawu kunye nokukhuthaza ukupheliswa kwebhaktheriya, kwimeko apho isifo senzeka ngenxa yosulelo. Ke, kubalulekile ukuba usele ulwelo oluninzi ukuthintela ukomisa, ukongeza ekunciphiseni ukusetyenziswa kweeproteni ukunqanda umonakalo omkhulu kwizintso.

Ngamanye amaxesha, ugqirha unokucebisa ukuba kusetyenziswe ii-antibiotics ukulwa usulelo okanye utofelo-gazi, oluhlala lubonakaliswa kubantwana abanesifo sorhudo olunegazi njengophawu. Kwiimeko ezinzima kakhulu, oko kukuthi, xa ukwenzakala kwezintso sele kuhambile kwaye umntu uneempawu zesifo sezintso ezinganyangekiyo, i-dialysis kunye nokufakelwa kwezintso kunokuba yimfuneko, apho izintso ezichaphazelekayo zithathelwe indawo yenye impilo. Jonga ukuba ukufakelwa kwezintso kwenziwa njani kwaye ukuba post-operative injani.

Ukuthintela i-SHU kubalulekile ukunqanda ukutya inyama ekrwada okanye engaphekwanga kakuhle, kuba zinokungcoliseka, kunye nokuthintela ukutya okuvela kubisi olungagalelwanga nzulu, kunye nokuhlamba izandla zakho kakuhle phambi kokulungiselela ukutya nasemva kokusebenzisa igumbi lokuhlambela.