Inaliti yeVinorelbine

Umxholo

• Ngaphambi kokufumana i-vinorelbine,
• IVinorelbine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:
• Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:
• Iimpawu zokudlula ngaphezulu zinokubandakanya:

I-Vinorelbine kufuneka inikwe kuphela phantsi kweliso likagqirha onamava ekusebenziseni amayeza e-chemotherapy.

IVinorelbine inokubangela ukwehla okukhulu kwenani leeseli zegazi kumongo wethambo lakho. Oku kunokubangela iimpawu ezithile kwaye kunokunyusa umngcipheko wokuba ube nosulelo olubi. Ugqirha wakho uya kuyalela iimvavanyo zaselebhu ngaphambi kwaye ngexesha lonyango lwakho ukujonga inani leeseli ezimhlophe egazini lakho. Ugqirha wakho unokunciphisa idosi yakho, okanye ukulibaziseka, ukuphazamisa, okanye uyeke unyango lwakho ukuba inani leeseli ezimhlophe zegazi liphantsi kakhulu. Ukuba ufumana naziphi na kwezi mpawu zilandelayo, tsalela umnxeba kwangoko: umkhuhlane, umqala obuhlungu, ukukhohlela okuqhubekayo kunye nokudibana, okanye ezinye iimpawu zosulelo.

Gcina lonke ixesha lokudibana nogqirha wakho kunye nelabhoratri. Ugqirha wakho uya kuyalela iimvavanyo ezithile zebhu ukujonga impendulo yomzimba wakho kwi vinorelbine.

IVinorelbine isetyenziswa yodwa kwaye idityaniswe namanye amayeza ukunyanga umhlaza wamaphaphu ongekho mncinci (NSCLC) osasazeke kwizicwili ezikufutshane okanye kwamanye amalungu omzimba. I-Vinorelbine ikudidi lwamayeza abizwa ngokuba yi-vinca alkaloids. Isebenza ngokunciphisa okanye ukumisa ukukhula kweeseli zomhlaza emzimbeni wakho.

IVinorelbine iza njengesisombululo (ulwelo) ukuze ifakwe ngaphakathi ngaphakathi (emthanjeni) ngugqirha okanye ngumongikazi kwiziko lonyango. Ihlala inikwa kube kanye ngeveki. Ubude bonyango buxhomekeke kwindlela ophendula ngayo umzimba wakho kunyango lwe-vinorelbine.

Kuya kufuneka uyazi ukuba i-vinorelbine kufuneka ilawulwe kuphela emthanjeni. Nangona kunjalo, inokuvuza kwizicubu ezijikelezileyo kubangele ukucaphuka okukhulu okanye ukonakala. Ugqirha wakho okanye umongikazi uya kubeka esweni indawo ekufuphi nalapho kufakwe iyeza. Ukuba unazo naziphi na kwezi mpawu zilandelayo, xelela ugqirha ngoko nangoko: iintlungu, ukurhawuzelela, ukuba bomvu, ukudumba, iblisters, okanye izilonda kufutshane nalapho lalifakwe khona iyeza.

I-Vinorelbine ngamanye amaxesha isetyenziselwa ukunyanga umhlaza wamabele, umhlaza we-esophagus (ityhubhu edibanisa umlomo nesisu), kunye ne-sarcomas yethishu ethambileyo (umhlaza owenza izihlunu). Thetha nogqirha wakho malunga neengozi zokusebenzisa eli yeza kwimeko yakho.

Eli yeza linokumiselwa ezinye izinto; buza ugqirha wakho okanye usokhemesti ngolwazi oluthe kratya.

Ngaphambi kokufumana i-vinorelbine,

• xelela ugqirha wakho kunye nosokhemisti ukuba ngaba uxabisa i-vinorelbine, nawaphi na amanye amayeza, okanye naziphi na izithako kwi-vinorelbine injection. Buza usokhemesti wakho uluhlu lwezithako.
• xelela ugqirha wakho kunye nosokhemesti ukuba loluphi olunye amayeza amiselweyo kunye nalawo angabhalwanga, iivithamini, izongezo zesondlo, kunye nemveliso yamayeza owathathayo okanye oceba ukuyithatha. Qiniseka ukuba ukhankanya nayiphi na kwezi zinto zilandelayo: ii-antifungals ezithile ezinje nge-itraconazole (Onmel, Sporanox, Tolsura) kunye ne ketoconazole; I-clarithromycin; I-HIV protease inhibitors kubandakanya indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, eKaletra, Technivie, Viekira), kunye ne-saquinavir (i-Invirase); okanye nefazodone. Ugqirha wakho unokufuna ukutshintsha amayeza akho okanye akubeke esweni ngononophelo kwiziphumo ebezingalindelekanga.
• xelela ugqirha wakho ukuba ukhe unesifo sesibindi.
• Xelela ugqirha wakho ukuba ukhulelwe, cwangcisa ukukhulelwa ,, okanye ucwangcise ukuba ngutata womntwana. Wena okanye iqabane lakho akufuneki ukuba ukhulelwe ngelixa ufumana inaliti ye-vinorelbine. Kufuneka uthathe uvavanyo lokukhulelwa ngaphambi kokuba uqale unyango ukuze uqiniseke ukuba awukhulelwe. Ukuba ungumfazi, sebenzisa ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-6 emva kwedosi yakho yokugqibela. Ukuba uyindoda, sebenzisa ulawulo lokuzalwa olusebenzayo ngexesha lonyango lwakho kunye neenyanga ezi-3 emva kwedosi yakho yokugqibela. Ukuba wena okanye iqabane lakho ukhulelwe ngelixa ufumana inaliti ye-vinorelbine, tsalela ugqirha wakho. IVinorelbine inokwenzakalisa umntwana ongekazalwa.
• xelela ugqirha wakho ukuba uncelisa. Ugqirha wakho uya kukuxelela ukuba ungancancisi ngexesha lonyango lwakho kunye neentsuku ezili-9 emva kwedosi yakho yokugqibela.
• Kuya kufuneka uyazi ukuba i-vinorelbine inokubangela ukuqhina. Thetha nogqirha wakho malunga nokutshintsha indlela otya ngayo kunye nokusebenzisa amanye amayeza ukuthintela okanye ukunyanga ukuqhina ngelixa uthatha i-vinorelbine.

Ugqirha wakho angakuxelela ukuba uqiniseke ukuba usele ngokwaneleyo amanzi, kwaye utye ukutya okunefayibha ephezulu njengeletisi, isipinatshi, ibroccoli, isikwashi, iimbotyi, amandongomane, iimbewu, iziqhamo, isonka sengqolowa, ipasta yengqolowa, okanye irayisi emdaka. Qiniseka ukuba ulandela imiyalelo ngononophelo.

IVinorelbine inokubangela iziphumo ebezingalindelekanga. Tshela ugqirha wakho ukuba ngaba ezinye zeempawu zinzima okanye azihambi:

• isicaphucaphu
• ukugabha
• urhudo
• Ukuphelelwa ngumdla wokutya
• ukuhla ukusinda
• utshintsho kwisakhono sokungcamla ukutya
• izilonda emlonyeni nasemqaleni
• ukulahlekelwa kwindlebe
• izihlunu, okanye iintlungu ezidibeneyo
• ukulahleka kweenwele
• ukunqongophala kwamandla, ukungaziva kakuhle, ukudinwa

Ezinye iziphumo ebezingalindelekanga zinokuba nzulu. Ukuba ufumana naziphi na kwezi mpawu okanye ezo zidweliswe kwicandelo LESILUMKISO ELIBALULEKILEYO, tsalela umnxeba kwangoko okanye ufumane unyango olungxamisekileyo:

• ukuphefumla kancinci okanye ukuphefumla nzima, ukukhohlela
• ukuqhina, isisu esibuhlungu, isicaphucaphu, ukugabha
• ukopha okungaqhelekanga okanye ukugruzuka
• urticaria, urhawuzelele, irhashalala, ukuphefumla nzima okanye ukuginya
• ukudumba kobuso, umqala, ulwimi, imilebe namehlo
• ukudumba okanye ukuxobuka kolusu
• tyheli kolusu okanye lamehlo, umchamo omnyama, isitulo esikhanyayo
• ukuba ndindisholo, ukurhawuzelela imvakalelo kulusu, ulusu olubuthathaka, ukuncipha kwendlela yokubamba, okanye ubuthathaka bemisipha
• ifiva, ingqele, umqala obuhlungu okanye ezinye iimpawu zosulelo
• iintlungu esifubeni, umphefumlo omfutshane, ukhohlela igazi
• bomvu, idumbile, ithenda, okanye ingalo efudumeleyo okanye umlenze

Thetha nogqirha wakho malunga nemingcipheko yokufumana inaliti yevinorelbine.

IVinorelbine inokubangela ezinye iziphumo ebezingalindelekanga. Biza ugqirha wakho ukuba unengxaki engaqhelekanga ngelixa uthatha eli yeza.

Ukuba uhlangabezana neziphumo ebezingalindelekanga ezimandundu, wena okanye ugqirha wakho ungathumela ingxelo kwiNkqubo yoKutya kunye nezoLawulo (i-FDA) yeMedWatch yeNkqubo yokuNgxelo ngezeMeko eziGwenxa kwi-Intanethi (http://www.fda.gov/Safety/MedWatch) okanye ngomnxeba ( 1-800-332-1088).

Kwimeko yokugqithisa, fowunela umnxeba wolawulo lwetyhefu kwi-1-800-222-1222. Ulwazi lukwafumaneka kwi-Intanethi kwi-https: //www.poisonhelp.org/help. Ukuba ixhoba liye lawa, laxhuzula, linengxaki yokuphefumla, okanye alikwazi ukuvuswa, ngoko nangoko lifowunele iinkonzo zongxamiseko ngo-911.

Iimpawu zokudlula ngaphezulu zinokubandakanya:

• izilonda emlonyeni nasemqaleni
• isisu esibuhlungu
• ukuqhina
• umkhuhlane, umqala obuhlungu, ingqele, okanye ezinye iimpawu zosulelo
• ukulahleka kwamandla okuhambisa izihlunu kunye nokuziva ulilungu lomzimba

Kubalulekile ukuba ugcine uluhlu olubhaliweyo lwawo onke amayeza owasebenzisayo amayeza owasebenzisayo, kunye nezinye iimveliso ezinjengeevithamini, iiminerali, okanye ezinye izongezo zokutya. Kuya kufuneka uze nolu luhlu qho xa undwendwela ugqirha okanye ungeniswe esibhedlele. Kukwabalulekile ulwazi ukuba uphathe nawe xa kukho imeko kaxakeka.

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• Didehydrodeoxynorvincaleukoblastine

^¶ Le mveliso inophawu akusekho kwimarike. Ezinye iindlela ezinokubakho zinokubakho.