Somatropin: yintoni, yintoni iziphumo kunye neziphumo ebezingalindelekanga

Umxholo

• Yenzelwe ntoni
• Kusetyenziswa kwanjani
• Iziphumo ebezingalindelekanga ezinokwenzeka
• Ngubani ongafanele asebenzise

I-Somatropin liyeza eliqukethe ukukhula kwehomoni yabantu, kubalulekile ekukhuleni kwamathambo kunye nezihlunu, ezisebenza ngokukhuthaza ukukhula kwamathambo, ukwandisa ubungakanani kunye nenani leeseli zemisipha kunye nokunciphisa ukuxinana kwamafutha emzimbeni.

Eli yeza inokufumaneka ezikhemesti nakwiivenkile ezinamagama orhwebo iGenotropin, iBiomatrop, iHormotrop, iHumatrope, iNorditropin, iSaizen okanye iSomatrop, kwaye ithengiswa kuphela ngommiselo.

I-Somatropin liyeza elitofwayo kwaye kufuneka lisetyenziswe ngokwemiyalelo kagqirha.

Yenzelwe ntoni

I-Somatropin isetyenziselwa ukunyanga ukusilela kokukhula ebantwaneni nakubantu abadala abanesifo sokukhula kwendalo. Oku kubandakanya abantu abanesiqu esifutshane ngenxa yesifo i-Noonan syndrome, Turner syndrome, Prader-Willi syndrome okanye ubude obufutshane xa kuzalwa kungabikho kuphucula ukukhula.

Kusetyenziswa kwanjani

I-Somatropin kufuneka isetyenziswe ngengcebiso kagqirha kwaye ifakwe kwisisipha okanye phantsi kolusu, kwaye idosi kufuneka ihlale ibalwa ngugqirha, kwimeko nganye. Nangona kunjalo, ngokubanzi idosi ekhuthazwayo yile:

• Abantu abadala ukuya kwiminyaka engama-35: Amanqanaba okuqala edosi ukusuka kwi-0.004 mg ukuya kwi-0.006 mg ye-somatropin kwi-kg nganye yesisindo somzimba esisetyenziswa yonke imihla phantsi kolusu ngokungaphantsi. Le dosi inokunyuswa iye kuthi ga kwi-0.025 mg ngeekhilogram ubunzima bomzimba ngosuku olusetyenziswe ngaphantsi;
• Abantu abadala abaneminyaka engama-35 nangaphezulu: idosi yokuqala isusela kwi-0.004 mg ukuya kwi-0.006 mg ye-somatropin nge-kg yesisindo somzimba yonke imihla esetyenziswa phantsi kolusu ngokungaphantsi, kwaye inokunyuswa iye kwi-0.0125 mg ngekg yesisindo somzimba ngosuku ngalunye;
• Abantwana: iidosi zokuqala ukusuka ku-0,024 mg ukuya ku-0,067 mg we-somatropin nge-kg yesisindo somzimba esisetyenziswe yonke imihla phantsi kolusu ngokungxama Kuxhomekeka kwimeko, ugqirha usenokubonisa i-0.3 mg ukuya kwi-0.375 mg nge-kg yesisindo somzimba ngeveki, yahlulwe yangamanani ama-6 ukuya kwayi-7, yafakwa usuku ngalunye ngaphantsi kwesikhumba.

Kubalulekile ukutshintsha iindawo phakathi kwenaliti nganye engaphantsi kwesikhumba, ukunqanda ukubakho kwempendulo kwindawo yenaliti njengokubomvu okanye ukudumba.

Iziphumo ebezingalindelekanga ezinokwenzeka

Ezinye zeziphumo ebezingalindelekanga ezinokubakho ngexesha lonyango lwe-somatropin yintloko ebuhlungu, iintlungu zemisipha, iintlungu kwindawo yenaliti, ubuthathaka, ukuqina kwesandla okanye iinyawo okanye ukugcinwa kwamanzi.

Ukongeza, kunokubakho ukwanda kwe-insulin ukuxhathisa, kubangela isifo seswekile ngokunyuka kweglucose egazini kunye nobukho beswekile kumchamo.

Ngubani ongafanele asebenzise

I-Somatropin akufuneki isetyenziswe ngabafazi abakhulelweyo okanye abancancisayo, abantu abanesifo esibuhlungu okanye isifutshane esifutshane esibangelwa sisisu sobuchopho kunye nabantu abaphikisayo kwi-somatropin okanye naliphi na icandelo lefomula.

Ukongeza, kubantu abane-2 yeswekile, i-hypothyroidism okanye i-psoriasis enganyangekiyo, i-somatropin kufuneka isetyenziswe ngononophelo kwaye kufuneka ihlolwe ngugqirha ngaphambi kokuyisebenzisa.