Unyango lwe-Eosinophilic Asthma

Umxholo

• Inhaled kunye ne-corticosteroids yomlomo
• Iinguqu zeLeukotriene
• Ibhayoloji
• Inhalers zokuhlangula
• I-Anticholinergics
• Ukuthatha

I-asthma ye-eosinophilic sisifo sombefu esihlala sikhula kamva ebomini. Umndilili weminyaka yokuqalisa uphakathi kweminyaka engama-35 ukuya kwengama-50 ubudala. Ingakhula kubantu abangazange bafunyaniswe ngaphambili benesifuba.

Olu hlobo lwe-asthma lubangelwa kukungena kweeseli zegazi ze-eosinophil. Ngelixa esona sizathu singaziwayo, ii-eosinophil zinokuba negalelo ekuvukeleni komoya kunye nokuxinana okubonwe kwiifom zesifuba.

I-asthma ye-eosinophilic inokubonisa iimpawu ezinzima kuneendlela ezinobunzima be-asthma. Unokuba ne-flare-ups rhoqo. Ukhetho kunyango luyafana nesifuba esinamandla, kodwa iindlela zonyango ezizezakho zihlala zinoburharha.

Thetha nogqirha wakho ngezi ndlela zilandelayo zisetyenziswayo ukunyanga olu hlobo lwesifuba.

Inhaled kunye ne-corticosteroids yomlomo

I-inhalled corticosteroids zihlala zililayini lokuqala lonyango lweendlela ezingapheliyo, kubandakanya i-eosinophilic, asthma. Basebenza ngokunciphisa ukudumba kwomoya okufaka isandla kwingxinano, ekuvumela ukuba uphefumle lula.

Unokufuna ezinye iinguqulelo ze-corticosteroids zesifo se-asthma ngomlomo ukuba iimpawu zakho zinzima kakhulu.

Nangona kunjalo, i-steroids yomlomo ibeka umngcipheko wexesha elide, kubandakanya:

• osteoporosis
• ukutyeba kwakho
• iswekile yemellitus

Iinguqu zeLeukotriene

La mayeza omlomo ahlala emiselwe abantu abane-asthma kunye ne-allergies. Basebenza ngokunciphisa ii-leukotrienes emzimbeni, ezinegalelo kukudumba.

Ugqirha wakho unokukunika enye yezi zinto zilandelayo:

• imontelukast sodium (Singulair)
• zafirlukast (Ukuchaneka)
• zileuton (Zyflo)

Ibhayoloji

I-Biologics yindlela ekhulayo yonyango lwe-asthma. La mayeza ahanjiswa ngenaliti, ngesiqhelo ngugqirha wakho. Banciphisa ukuvuvukala ngokujolisa kwiimolekyuli ezivuthayo, iiseli, kunye neentsholongwane.

Ngesi sizathu, i-biologics ithathwa njenge inika unyango "olwenziwe" ngakumbi xa kuthelekiswa namanye amayeza esifuba.

Unokuba ngumgqatswa we-biologics ukuba uyaqhubeka nokufumana ii-flare-ups rhoqo ngaphandle kokuthatha amayeza olawulo kunye nokuphepha izinto ezinokubangela.

I-Biologics inokunciphisa isifuba sasebusuku, kunye nokunciphisa inani lotyelelo esibhedlele kuhlaselo lwesifuba.

Okwangoku kukho iintlobo ezintlanu zebhayoloji ezikhoyo kunyango lwesifo sombefu:

• ibenralizumab (Fasenra)
• dupilumab (Iphindwe kabini)
• mepolizumab (iNucala)
• i-omalizumab (iXolair)
• I-reslizumab (iCinqair)

Kwezi biologics, iFasenra, iNucala, kunye neCinqair zonke zijolise kwii-eosinophil ngokukodwa. Uninzi lwe-biologics luphuhliso lonyango olujolise ngakumbi.

Ukuba ugqirha wakho ucebisa i-biologics kwi-asthma yakho ye-eosinophilic, unokulindela ukufumana ezi zitofu rhoqo kwiiveki ezi-2 ukuya kwezi-8 ngaphezulu kweenyanga ezi-4.

Inhalers zokuhlangula

Ngelixa ingelohlobo lonyango lwexesha elide, isengumbono olungileyo ukuba ube ne-inhaler yokuhlangula ngesandla ukuba une-asthma eosinophilic.

Ikwabizwa ngokuba yi-inhaler yokunceda ngokukhawuleza, la mayeza asebenza ngokunciphisa iimpawu zokutsha kunye nokuvula iindlela zakho zomoya ukunceda ukuthintela uhlaselo lwesifuba.

Ingxaki ngabahlanguli be-inhalers kukuba abayi kuthintela iimpawu zesifuba njengabalawuli bexesha elide. Ukuthembela kwezi ntlobo ze-inhalers rhoqo kunokubenza bangasebenzi kakuhle kuba imiphunga yakho iya kubaqhela.

Biza ugqirha wakho ukuba usebenzisa i-inhaler yakho yokuhlangula ngaphezulu kwamaxesha ambalwa ngeveki.

I-Anticholinergics

I-Anticholinergics ngamayeza athintela i-neurotransmitter ebizwa ngokuba yi-acetylcholine. La machiza ngokwesiko anyanga ukungasebenzi kakuhle kunye nesinyithi esisebenzayo, kunye nesifo esinganyangekiyo semiphunga (COPD).

Ezi ntlobo zamayeza zinokukunceda ukunyanga isifo sombefu. Anticholinergics phumla izihlunu zomoya kwaye zikuncede uphefumle lula.

Ukuthatha la mayeza kungenza kungabi lula ukuba uzakufuna i-steroids yomlomo ngaphezulu kwexesha elide.

Ukuthatha

I-asthma ye-eosinophilic yenye yezona zinto zinzima kakhulu ukunyanga i-asthma. Kuya kufuneka ukuba uzame iindlela ezahlukeneyo ukuze ubone ukuba zeziphi ezisebenza kakuhle.

Isifuba sakho somzimba sithathwa ngokuba "silawulwa kakuhle" ukuba unempawu zeentsuku ezi-2 ngeveki okanye ezimbalwa.

Thetha nogqirha wakho ukuba ufumana iimpawu zesifuba rhoqo kwaye ukuba imeko yakho iphazamisa imisebenzi yemihla ngemihla. Banokumisela amayeza exesha elide okanye i-biologics ukunceda ukuphucula iimpawu zakho kunye nomgangatho wobomi.

Ukulawula iimpawu ze-asthma ye-eosinophilic kunokunceda ukunciphisa umngcipheko wokuqhekeka kwemiphunga kunye nezinye iingxaki zexesha elide.

Unako ukuphucula iziphumo zakho zonyango ngokunyamekela impilo yakho yonke ngokusemandleni akho, kuquka:

• ukutya okusempilweni
• ukulala ngokwaneleyo
• ulawulo loxinzelelo

Ukuphepha izinto ezinokubangela, ezinje ngoxinzelelo, i-allergies, kunye neekhemikhali ezicaphukisayo, kunokunciphisa umngcipheko wokuqhambuka.