Iimpawu zesifo sikaCushing, oonobangela kunye nonyango

Umxholo

• Iimpawu eziphambili
• Unobangela wesifo sikaCushing
• Uxilongo lwenziwa njani
• Unyango lwenziwa njani
• Iingxaki ezinokwenzeka

Isifo sikaCushing's syndrome, ekwabizwa ngokuba sisifo sikaCushing okanye i-hypercortisolism, lutshintsho lwehomoni olubonakaliswa ngokwanda kwehomoni cortisol egazini, ekhokelela ekubonakaleni kweempawu ezithile zesifo njengokufumana ubunzima ngokukhawuleza kunye nokuqokelelana kwamafutha emzimbeni. ummandla wesisu kunye nobuso, ukongeza kuphuhliso lwemizila ebomvu emzimbeni kunye nolusu olunamafutha oluqhelene namabala, umzekelo.

Ke ngoko, kubukho beempawu kunye neempawu, kuyacetyiswa ukuba ubonane ne-endocrinologist ukuze kuvavanywe igazi kunye nokucinga, kwaye ke, olona nyango lufanelekileyo lunokuboniswa, olunokwenziwa ngokusetyenziswa kwamayeza okanye uqhaqho, umzekelo.

Iimpawu eziphambili

Olona phawu luphawu lweCushing's syndrome kukuqokelelwa kwamafutha kuphela kummandla wesisu nasebusweni, okwaziwa ngokuba bubuso benyanga. Ukongeza, ezinye iimpawu kunye neempawu ezinokuthi zihambelane nesi sifo zi:

• Ukutyeba ngokukhawuleza, kodwa iingalo kunye nemilenze ebhityileyo;
• Ukubonakala kwemibala ebomvu, ebomvu esiswini;
• Ukubonakala kweenwele ebusweni, ngakumbi kwimeko yabasetyhini;
• Ukwanda koxinzelelo;
• Isifo seswekile, kuba kuqhelekile ukuba kwinqanaba eliphezulu leswekile egazini;
• Ukunciphisa i-libido kunye nokuzala;
• Umjikelo wokuya esikhathini ngokungaqhelekanga;
• Buthathaka kwezihlunu;
• Ulusu olunamafutha kunye namaqhakuva;
• Ubunzima bokupholisa amanxeba;
• Ukuvela kwamabala amfusa.

Ihlala iqaphela ukubonakala kweempawu ezininzi ngaxeshanye kwaye zixhaphake kakhulu kwizigulana ezinezifo ezifana nesifo samathambo, isifuba, ilupus okanye emva kokufakelwa kwamalungu kwaye zithatha iicorticosteroids kangangeenyanga ezininzi ngexabiso eliphezulu. Kwimeko yabantwana abane-Cushing's syndrome, ukukhula kancinci, ukuphakama okuphantsi, ukwanda kobuso kunye neenwele zomzimba kunye nenkqayi kunokuqatshelwa.

Unobangela wesifo sikaCushing

Isifo esenzeka ngenxa yokunyuka kwamanqanaba e-cortisol egazini, enokwenzeka ngenxa yeemeko ezininzi. Unobangela oqhelekileyo woku kunyuka kwaye uthanda ukuphuhliswa kwesi sifo kukusetyenziswa ixesha elide kunye needosi eziphezulu ze-corticosteroids, edla ngokubonakaliswa kunyango lwezifo ezifana ne-lupus, i-rheumatoid arthritis kunye ne-asthma, ukongeza ekubonakalisweni kwayo abantu esele benofakelo lwezitho.

Ukongeza, isifo sikaCushing sinokwenzeka ngenxa yobukho bexesha kwi-pituitary gland, efumaneka kwingqondo, ekhokelela ekuphelisweni kwemveliso kwimveliso ye-ACTH kwaye, ngenxa yoko, ukwanda kwemveliso yecortisol, enokufunyanwa. kwiindawo eziphezulu egazini. Yazi ukuba yeyiphi i-hormone ye-cortisol.

Uxilongo lwenziwa njani

Ukuchongwa kwesifo sikaCushing's kufuneka kwenziwe yi-endocrinologist esekwe kuvavanyo lweempawu kunye neempawu ezibonakaliswa ngumntu, imbali yezempilo kunye novavanyo lwelabhoratri okanye uvavanyo.

Ke, kunokucetyiswa ngugqirha ukuba enze iiyure ezingama-24 zegazi, amathe kunye novavanyo lomchamo ukujonga amanqanaba e-cortisol kunye ne-ACTH ejikelezayo emzimbeni. Ukongeza, uvavanyo lokukhuthaza nge-dexamethasone lunokucetyiswa, eliliyeza elonyusa ukusebenza kwe-pituitary gland kwaye, yiyo loo nto, inokunceda ukuxilongwa. Ngenxa yokusetyenziswa kwe-dexamethasone, kunokucetyiswa ukuba umntu angeniswe esibhedlele malunga neentsuku ezimbini.

Ukujonga ubukho be-tumor kwi-pituitary gland, ugqirha unokucela ukuba kusebenze i-computed tomography okanye i-imagination magnetic resonance, umzekelo. Kwiimeko ezininzi, kuye kufuneke ukuphinda uvavanyo lokuqinisekisa ukuxilongwa kunye nokuqala unyango oluchanekileyo, njengoko ezinye iimpawu ziqhelekile kwezinye izifo, ezinokwenza uxilongo lube nzima.

Unyango lwenziwa njani

Unyango lwe-Cushing's syndrome kufuneka ikhokelwe yi-endocrinologist kwaye iyahluka ngokuxhomekeka kwisizathu sesifo. Xa esi sifo sibangelwa kukusetyenziswa kwexesha elide kwe-corticosteroids, ukuhla kwethamo leyeza kubonisiwe, ngokwesikhokelo sikagqirha kwaye, ukuba kunokwenzeka, ukunqunyanyiswa.

Kwelinye icala, xa i-Cushing's syndrome ibangelwa lithumba, unyango luhlala lubandakanya utyando lokususa ithumba kwaye emva koko wenze i-radiotherapy okanye i-chemotherapy. Ukongeza, ngaphambi kotyando okanye xa ithumba lingenakususwa, ugqirha unokucebisa ukuba isigulana sithathe amayeza ukulawula imveliso ye-cortisol.

Ukunciphisa iimpawu zesi sifo kubalulekile ukugcina ukutya okungenayo ityuwa neswekile kwaye utye iziqhamo kunye nemifuno yonke imihla kuba kukutya okuneevithamini kunye neeminerals kwaye kunceda ukomeleza amajoni omzimba.

Iingxaki ezinokwenzeka

Xa unyango lwe-Cushing's syndrome lungakhange lwenziwe ngokuchanekileyo, kunokwenzeka ukuba kukho ukungabikho kolawulo lwehomoni olunokubeka ubomi bomntu engozini. Kungenxa yokuba amanqanaba e-hormone angalinganiyo anokubangela ukungasebenzi kakuhle kwezintso kunye nokusilela komzimba.