Isifo se-veno-occlusive isifo

I-Pulmonary veno-occlusive isifo (PVOD) sisifo esinqabileyo. Kukhokelela kuxinzelelo lwegazi oluphezulu kwimithambo yemiphunga (uxinzelelo lwegazi).

Kwiimeko ezininzi, unobangela wePVOD awaziwa. Uxinzelelo lwegazi oluphezulu lwenzeka kwimithambo yegazi yemiphunga. Le mithambo yemiphunga ixhunyaniswe ngqo kwicala lasekunene lentliziyo.

Le meko inokuthi ihambelane nosulelo lwentsholongwane. Inokwenzeka njengengxaki yezifo ezithile ezinje nge-lupus, okanye ukufakelwa komongo wethambo.

Esi sifo sixhaphake kakhulu ebantwaneni nakubantu abadala abancinci. Njengoko esi sifo siba sibi ngakumbi, sibangela:

• Imithambo emincinci yemiphunga
• Uxinzelelo lwegazi lwe-pulmonary artery
• Ukudibanisa nokudumba kwemiphunga

Izinto ezinokubangela umngcipheko kwi-PVOD zibandakanya:

• Imbali yosapho yale meko
• Ukutshaya
• Ukubonakaliswa kwezinto ezifana ne-trichlorethylene okanye amayeza e-chemotherapy
• Inkqubo ye-sclerosis (isifo se-autoimmune skin disorder)

Iimpawu zinokubandakanya nayiphi na kwezi zinto zilandelayo:

• Ukuqhawukelwa ngumphefumlo
• Ukukhohlela owomileyo
• Ukukhathala ekusebenzeni
• Ukufa isiqaqa
• Ukukhohlela igazi
• Ubunzima bokuphefumla ngelixa ulele tyaba

Umboneleli wezempilo uya kukuvavanya kwaye akubuze ngembali yakho yezonyango kunye neempawu.

Uviwo lunokutyhila:

• Ukwanda koxinzelelo kwimithambo yentamo
• Iiklabhu zeminwe
• Umbala oluhlaza okwesibhakabhaka ngenxa yokunqongophala kweoksijini (cyanosis)
• Ukudumba emilenzeni

Umboneleli wakho unokuva izandi zentliziyo engaqhelekanga xa umamele isifuba kunye nemiphunga ngestethoscope.

Olu vavanyo lulandelayo lunokwenziwa:

• Iigesi zegazi
• I-oximetry yegazi
• I-x-ray yesifuba
• Isifuba CT
• Ukucinywa kwentliziyo
• Uvavanyo lomsebenzi wemiphunga
• Echocardiogram
• I-biopsy yemiphunga

Okwangoku alukho unyango olusebenzayo. Nangona kunjalo, la mayeza alandelayo anokuba luncedo kwabanye abantu:

• Amayeza ayenza banzi imithambo yegazi (vasodilators)
• Amayeza alawula impendulo yomzimba (njenge-azathioprine okanye i-steroids)

Ukufakelwa kwemiphunga kunokufuneka.

Isiphumo sihlala sihlwempuzeke kakhulu kwiintsana, ngenqanaba lokusinda kwiiveki nje ezimbalwa. Ukusinda kubantu abadala kunokuba ziinyanga ukuya kwiminyaka embalwa.

Iingxaki ze-PVOD zinokubandakanya:

• Ubunzima bokuphefumla obuba mandundu, kubandakanya nasebusuku (i-apnea yokulala)
• Uxinzelelo lwegazi
• Ukusilela kwentliziyo esekunene (cor pulmonale)

Tsalela umnikezeli wakho ukuba unempawu zolu gulo.

Isifo esiqhelekileyo se-vaso-occlusive

• Inkqubo yokuphefumla

UChin K, uChannick RN. Uxinzelelo lwegazi. Ku: Broaddus VC, Mason RJ, Ernst JD, et al, ii-eds. Incwadi kaMurray kunye neNadel yeyeza lokuphefumla. Umhla wesi-6.IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 58.

UChurg A, uWight JL. Uxinzelelo lwegazi. Ku: Leslie KO, Wick MR, ii-eds. Ukusebenza kwePulmonary Pathology: Indlela yokuChonga. Ngomhla wesi-3. IPhiladelphia, PA: Elsevier; I-2018: isahluko 12.

UMclaughlin VV, uHumbert M.Uxinzelelo lwegazi lwePulmonary. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2019: isahluko 85.