Ukulimala kwesibindi

Ukulimala kwesibindi okubangelwa sisiyobisi kukwenzakala kwesibindi esinokwenzeka xa uthatha amayeza athile.

Ezinye iintlobo zokulimala kwesibindi zibandakanya:

• Intsholongwane yesibindi
• Utywala hepatitis
• Ngokuzimela hepatitis
• Ukugcwala kwentsimbi
• Isibindi esinamafutha

Isibindi sinceda umzimba ukuba uphule amayeza athile. Oku kubandakanya ezinye iziyobisi ozithenga ekhawuntareni okanye umboneleli wakho wezempilo ukumisela. Nangona kunjalo, le nkqubo ihamba kancinci kwabanye abantu. Oku kunokukwenza ukuba ufumane umonakalo wesibindi.

Amanye amachiza anokubangela i-hepatitis ngeedosi ezincinci, nokuba inkqubo yokonakala kwesibindi iqhelekile. Iidosi ezinkulu zamayeza amaninzi zinokonakalisa isibindi esiqhelekileyo.

Amachiza amaninzi ahlukeneyo anokubangela i-hepatitis ebangelwa ngamachiza.

Iipainkillers kunye nokunciphisa umkhuhlane oqukethe i-acetaminophen ngoyena nobangela wokulimala kwesibindi, ngakumbi xa kuthathwa iidosi ezinkulu kunezo zicetyiswayo. Abantu abasela utywala ngokugqithileyo kunokwenzeka ukuba babe nale ngxaki.

Izidakamizwa ezichasayo ezichasayo (i-NSAIDs), ezifana ne-ibuprofen, i-diclofenac kunye ne-naproxen, inokubangela ukuba i-hepatitis ibangelwa iziyobisi.

Ezinye iziyobisi ezinokubangela ukulimala kwesibindi zibandakanya:

• Amiodarone
• I-Anabolic steroids
• Iipilisi zokulawula inzala
• Chlorpromazine
• Erythromycin
• IHalothane (uhlobo lweanesthesia)
• IMethyldopa
• Isoniazid
• Imethotrexate
• Iingxelo
• Iziyobisi zeSulfa
• Iitetracyclines
• Amoxicillin-clavulanate
• Amanye amayeza okulwa ukuxhuzula

Iimpawu zinokubandakanya

• Intlungu zesisu
• Umchamo omnyama
• Urhudo
• Ukudinwa
• Ifiva
• Intloko ebuhlungu
• I-jaundice
• Ukuphelelwa ngumdla wokutya
• Isicaphucaphu nokugabha
• Irhashalala
• Izitulo ezimhlophe okanye ezimdaka

Uya kuvavanywa igazi ukujonga ukusebenza kwesibindi. Ii-enzyme zesibindi ziya kuba phezulu ukuba unemeko.

Umboneleli wakho uya kwenza uvavanyo lomzimba ukukhangela isibindi esandisiweyo kunye nokuthamba kwesisu kwindawo ephezulu yesisu. Irhashalala okanye umkhuhlane unokuba yinxalenye yezinye zeziyobisi ezichaphazela isibindi.

Olona nyango kuphela kwimeko ezininzi zomonakalo wesibindi obangelwe kukuthatha ichiza kukuyeka ichiza elibangele ingxaki.

Nangona kunjalo, ukuba uthathe iidosi eziphezulu ze-acetaminophen, kuya kufuneka unyangwe ukwenzakala kwesibindi kwisebe likaxakeka okanye olunye ulungiselelo lonyango ngokukhawuleza.

Ukuba iimpawu zinzima, kuya kufuneka uphumle kwaye uphephe ukuzilolonga kakhulu, utywala, i-acetaminophen, kunye nezinye izinto ezinokwenzakalisa isibindi. Kuya kufuneka ufumane ulwelo ngomthambo ukuba isicaphucaphu nokugabha zibi kakhulu.

Ukulimala kwesibindi okubangelwa ziziyobisi kuhlala kudlula kwiintsuku okanye iiveki emva kokuba uyekile ukuthatha ichiza elibangele oko.

Rhoqo, ukulimala kwesibindi okubangelwa sisiyobisi kungakhokelela ekusileleni kwesibindi.

Fowunela umnikezeli wakho ukuba:

• Uba neempawu zokulimala kwesibindi emva kokuba uqale ukuthatha iyeza elitsha.
• Ufumaniswe ukuba unobungozi besibindi obubangelwa ziziyobisi kwaye iimpawu zakho azibangcono emva kokuba uyekile ukuthatha iyeza.
• Uphuhlisa naziphi na iimpawu ezintsha.

Ungaze usebenzise ngaphezulu kwethamo elicetyiswayo lamayeza angaphaya kwekhawuntare ane-acetaminophen (iTylenol).

MUSA ukuwathatha la mayeza xa usela kakhulu okanye rhoqo; thetha nomboneleli wakho malunga namayeza akhuselekileyo.

Soloko uxelela umboneleli wakho ngawo onke amayeza owathathayo, kubandakanya amayeza angaphezulu kwekhawuntari kunye namalungiselelo okanye amalungiselelo ongezelelweyo. Oku kubaluleke kakhulu ukuba unesifo sesibindi.

Thetha nomboneleli wakho ngamanye amayeza onokufuna ukuwaphepha. Umboneleli wakho angakuxelela ukuba ngawaphi amayeza akhuselekileyo kuwe.

Hepatitis ityhefu; I-hepatitis ebangelwa ziziyobisi

• Inkqubo yokwetyisa
• I-hepatomegaly

IChalasani NP, iHayashi PH, iBonkovsky HL, et al. Isikhokelo seKlinikhi ye-ACG: ukufumanisa isifo kunye nokulawulwa kokulimala kwesibindi okubangelwa sisiyobisi. NdinguJ Gastroenterol. Ngo-2014; 109 (7): 950-966. IINKCUKACHA: 24935270 www.ncbi.nlm.nih.gov/pubmed/24935270.

IChitturi S, Teoh NC, Farrell GC kunye ne-GI. I-Hepatic drug metabolism kunye nesifo sesibindi esibangelwa ngamachiza. Ku: UFeldman M, uFriedman LS, uBrandt LJ, ii-eds. Sleisenger kunye neFordtran's Gastrointestinal and Liver Disease. Ngomhla we-10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahl 88.

UDevarbhavi H, uBonkovsky HL, uRusso M, uChalasani N.Ukulimala kwesibindi okubangelwa ziziyobisi. Ku: Sanyal AJ, Boyer TD, Lindor KD, Terrault NA, ii-eds. I-Zakim kunye neBoyer's Hepatology. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 56.

I-ND. Isibindi kunye nenyongo. Ku: Kumar V, Abbas AK, Aster JC, ii-eds. Robbins kunye neCotran Pathologic Isiseko seZifo. Umhla we-9. IPhiladelphia, PA: Elsevier Saunders; 2015: isahl 18.