Cholesterol - unyango lweziyobisi

Umzimba wakho ufuna icholesterol ukuze usebenze kakuhle. Kodwa icholesterol eyongezelelekileyo egazini lakho ibangela ukuba iidiphozithi zakheke kwiindonga zangaphakathi zemithambo yegazi lakho. Olu lwakhiwo lubizwa ngokuba lucwecwe. Iyacutha imithambo yakho kwaye inokunciphisa okanye iyeke ukuhamba kwegazi. Oku kunokukhokelela ekuhlaselweni yintliziyo, ukubetha, kunye nokunciphisa imithambo kwenye indawo emzimbeni wakho.

Iitatins kucingelwa ukuba zezona ziyobisi zisetyenziswayo kubantu abafuna amayeza ukwehlisa icholesterol yabo.

Hyperlipidemia - unyango lweziyobisi; Ukuqina kwemithambo-istin

Iitatins zinciphisa umngcipheko wesifo sentliziyo, ukubetha, kunye nezinye iingxaki ezinxulumene noko. Benza oku ngokunciphisa i-cholesterol yakho ye-LDL (embi).

Uninzi lwexesha uyakufuna ukuthatha eli yeza ubomi bakho bonke. Ngamanye amaxesha, ukutshintsha indlela ophila ngayo kunye nokulahla ubunzima obungaphezulu kunokukuvumela ukuba uyeke ukuthatha eli yeza.

Ukuba ne-LDL esezantsi kunye ne-cholesterol iyonke kunciphisa umngcipheko wesifo sentliziyo. Kodwa ayinguye wonke umntu ekufuneka ethathe i-statins ukunciphisa i-cholesterol.

Umboneleli wakho wezempilo uya kuthatha isigqibo ngonyango lwakho ngokusekwe:

• Iyonke, i-HDL (elungileyo), kunye ne-LDL (embi) amanqanaba e-cholesterol
• Iminyaka yakho
• Imbali yakho yeswekile, uxinzelelo lwegazi oluphezulu, okanye isifo sentliziyo
• Ezinye iingxaki zempilo ezinokubangelwa yi-cholesterol ephezulu
• Nokuba uyatshaya okanye awutshayi
• Umngcipheko wesifo sentliziyo
• Ubuhlanga bakho

Kuya kufuneka uthathe ii-statins ukuba unama-75 okanye ungaphantsi, kwaye unembali:

• Iingxaki zentliziyo ngenxa yokuxinana kwemithambo entliziyweni
• Stroke okanye i-TIA (ukubetha okuncinci)
• I-aortic aneurysm (i-bulge kwimithambo ephambili emzimbeni wakho)
• Ukunciphisa imithambo kwimilenze yakho

Ukuba uneminyaka engaphezu kwama-75, umboneleli wakho unokumisela idosi esezantsi yesistin. Oku kunokunceda ukunciphisa iziphumo ebezingalindelekanga ezinokubakho.

Kuya kufuneka uthathe ii-statins ukuba i-cholesterol yakho ye-LDL iyi-190 mg / dL okanye ngaphezulu. Kuya kufuneka uthathe ii-statins ukuba i-cholesterol yakho ye-LDL iphakathi kwama-70 no-189 mg / dL kunye:

• Unesifo seswekile kwaye uphakathi kweminyaka engama-40 ukuya kwengama-75
• Unesifo seswekile kunye nomngcipheko ophezulu wesifo sentliziyo
• Unomngcipheko omkhulu wesifo sentliziyo

Wena kunye nomboneleli wakho unokufuna ukuqaphela i-statins ukuba i-cholesterol yakho ye-LDL ingama-70 ukuya ku-189 mg / dL kwaye:

• Unesifo seswekile kunye nomngcipheko ophakathi wesifo sentliziyo
• Unomngcipheko ophakathi wesifo sentliziyo

Ukuba unomngcipheko ophezulu wesifo senhliziyo kwaye i-cholesterol yakho ye-LDL ihlala phezulu nangona unyango lwe-statin, umboneleli wakho unokuqwalasela la mayeza ngaphezu kweemimiselo:

• Ezetimibe
• Ii-PCSK9 inhibitors, ezinje nge-alirocumab kunye ne-evolocumab (Repatha)

Oogqirha basebenzise ukuseta inqanaba ekujoliswe kulo kwi-cholesterol yakho ye-LDL. Kodwa ngoku ukugxila kunciphisa umngcipheko weengxaki ezibangelwa kukucuthwa kwemithambo yakho. Umboneleli wakho unokujonga amanqanaba akho e-cholesterol. Kodwa ukuvavanywa rhoqo akufuneki.

Wena kunye nomnikezeli wakho niya kuthatha isigqibo sokuba yeyiphi idosi yestermin ekufuneka niyithathile. Ukuba unemingcipheko, unokufuna ukuthatha amanani aphezulu. okanye ukongeza ezinye iintlobo zamachiza. Izinto eziya kuqwalaselwa ngumboneleli wakho xa ukhetha unyango lwakho zibandakanya:

• Amanqaku akho e-HDL, kunye ne-LDL ye-cholesterol ngaphambi konyango
• Ingaba unesifo se-coronary disease (imbali ye-angina okanye ukuhlaselwa yintliziyo), imbali yokubetha, okanye imithambo encinci emilenzeni yakho
• Nokuba unesifo seswekile
• Nokuba uyatshaya okanye unoxinzelelo oluphezulu lwegazi

Iidosi eziphezulu zingakhokelela kwiziphumo ebezingalindelekanga ekuhambeni kwexesha. Ke umboneleli wakho uya kuqwalasela iminyaka yakho kunye nemingcipheko kwimiphumo emibi.

• Icholesterol
• Ukwakhiwa kweplaque kwimithambo

Umbutho weSwekile yaseMelika. Isifo sentliziyo kunye nolawulo lomngcipheko: imigangatho yokhathalelo lonyango kwisifo seswekile-2020. Unonophelo lweSwekile. 2018; 43 (iSuppl 1): S111-S134. IINKCUKACHA: 31862753.

UFox CS, uGold SH, noAnderson C, et al. Uhlaziyo kuthintelo lwesifo sentliziyo kubantu abadala abanesifo seswekile seswekile ekukhanyeni kobungqina bamva nje: ingxelo yezenzululwazi evela kwiAmerican Heart Association kunye neAmerican Diabetes Association. Ukujikeleza. 2015; 132 (8): 691-718. IINKCUKACHA: 26246173 pubmed.ncbi.nlm.nih.gov/26246173/.

UGenest J, uLibby P.Lipoprotein ukuphazamiseka kunye nesifo sentliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ii-eds. Isifo sentliziyo seBraunwald: Incwadi yesifundo seMpilo yeNtliziyo. Ngomhla we-11. IPhiladelphia, PA: Elsevier; I-2019: isahluko 48.

I-Grundy SM, iLitye NJ, iBaleyy AL, et al. 2018 AHA / ACC / AACVPR / AAPA / ABC / ACPM / ADA / AGS / APhA / ASPC / NLA / PCNA Isikhokelo kulawulo lwe-cholesterol yegazi: ingxelo ye-American College of Cardiology / American Heart Association Task Force kwi-Clinical Practice Guidelines . J NdinguColl Cardiol. Ngo-2019; 73 (24): e285-e350. IINKCUKACHA: 30423393 pubmed.ncbi.nlm.nih.gov/30423393/.

IiNkonzo zoThintelo ze-US. Isiteyitimenti sokugqibela sesindululo: ukusetyenziswa kwe-statin kuthintelo oluphambili lwesifo sentliziyo kubantu abadala: amayeza othintelo. www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/statin-use-in-adult-preventive-medication1. Ukuhlaziywa kweyeNkanga ngo-2016. Ifikeleleke ngo-Matshi 3, 2020.

Isishwankathelo seengcebiso ngeeNkonzo zoThintelo ze-US. Ukusetyenziswa kwe-Statin kuthintelo oluphambili lwesifo sentliziyo kubantu abadala: amayeza othintelo. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adult-preventive-medication. Ukuhlaziywa kweyeNkanga ngo-2016. Kufikeleleke ngoFebruwari 24, 2020.

• UAngina
• I-angioplasty kunye nokubekwa kwindawo entle-umthambo wecarotid
• I-angioplasty kunye nokubekwa ngokufanelekileyo - imithambo yendlela
• Isifo semithambo yeCarotid
• Utyando lweCarotid-luvulekile
• Isifo sentliziyo
• Ukuhlaselwa yintliziyo
• Utyando lwentliziyo ngokudlula
• Utyando lwentliziyo olugqithisileyo- olungenayo intsholongwane
• Isifo sentliziyo kunye nokutya
• Amanqanaba aphezulu e-cholesterol egazini
• Umda we-peripheral artery-umlenze

• Ukulungiswa kwesisu se-aortic aneurysm - ukukhutshwa okuvulekileyo
• Angina - ukubhobhoza
• UAngina-yintoni oza kuyibuza ugqirha wakho
• I-Angioplasty kunye nokubekwa kwindawo entle-umthambo we-carotid-ukukhutshwa
• I-angioplasty kunye nokubekwa ngokuqinileyo-imithambo yendlela-yokukhutshwa
• Ukulungiswa kwe-aortic aneurysm-endovascular-discharge
• I-Atrial fibrillation - ukukhutshwa
• Ibhotolo, imajarini neeoli zokupheka
• Utyando lweCarotid-ukukhutshwa
• Ikholesterol - yintoni ekufuneka uyibuze kugqirha wakho
• Ukulawula uxinzelelo lwegazi oluphezulu
• Kuchazwe amafutha ezempilo
• Iingcebiso zokutya okukhawulezayo
• Ukuhlaselwa yintliziyo - ukukhutshwa
• Ukuhlaselwa sisifo sentliziyo- ukubuza ugqirha
• Isifo sentliziyo - umngcipheko
• Ukungaphumeleli kwentliziyo-yintoni oza kuyibuza ugqirha wakho
• Uxinzelelo lwegazi oluphezulu- yintoni oza kuyibuza ugqirha wakho
• Ukutya kweMeditera
• Umda we-peripheral artery-umlenze-ukukhutshwa
• Stroke - ukubhobhoza

• Icholesterol
• Amayeza eCholesterol
• Cholesterol ephezulu kubantwana nakwishumi elivisayo
• I-LDL: I-cholesterol "engalunganga"
• Iingxelo