I-analphic nephropathy

I-analgesic nephropathy ibandakanya ukonakala kwenye okanye zombini izintso ezibangelwa kukuvezwa kakhulu kwimixube yamayeza, ngakumbi amayeza eentlungu zekhawuntareni.

I-analgesic nephropathy ibandakanya ukonakala ngaphakathi kwezintso. Kubangelwa kukusetyenziswa kwexesha elide kwe-analgesics (amayeza entlungu), ngakumbi amayeza e-counter-the-counter (OTC) aqukethe i-phenacetin okanye i-acetaminophen, kunye ne-nonsteroidal anti-inflammatory drug (NSAIDs), ezinje nge aspirin okanye ibuprofen.

Le meko ihlala isenzeka njengesiphumo sokuzinyanga, rhoqo kuhlobo oluthile lweentlungu ezingapheliyo.

Izinto zomngcipheko zibandakanya:

• Ukusetyenziswa kwee-analgesics ze-OTC ezinesithako esingaphezulu kwesinye
• Ukuthatha iipilisi ezi-6 nangaphezulu ngosuku kangangeminyaka emi-3
• Iintloko ezingapheliyo, iintlungu zokuya exesheni, umqolo obuhlungu, okanye iintlungu zemisipha
• Utshintsho lweemvakalelo okanye lokuziphatha
• Imbali yokuziphatha okuxhomekekileyo kubandakanya ukutshaya, ukusetyenziswa kotywala, kunye nokusetyenziswa gwenxa kwezixhobo zokuthomalalisa

Kungangabikho mpawu ekuqaleni. Ixesha elingaphezulu, njengoko izintso zonzakele liyeza, iimpawu zesifo sezintso ziya kukhula, kubandakanya:

• Ukudinwa, ubuthathaka
• Ukwanda kokuhamba rhoqo komchamo okanye ukungxamiseka
• Igazi kumchamo
• Intlungu yeflank okanye umqolo obuhlungu
• Ukuncipha kwemveliso yomchamo
• Ukuncipha kokuncipha, kubandakanya ukozela, ukudideka kunye nokudinwa
• Ukuhla kwemvakalelo, ukuba ndindisholo (ngakumbi kwimilenze)
• Isicaphucaphu, ukugabha
• Ukutyumza ngokulula okanye ukopha
• Ukudumba (ukudumba) emzimbeni wonke

Umboneleli wezempilo uyakukuvavanya akubuze malunga neempawu zakho. Ngexesha loviwo, umboneleli wakho unokufumana:

• Uxinzelelo lwegazi luphezulu.
• Xa umamele nge-stethoscope, intliziyo yakho kunye nemiphunga inezandi ezingaqhelekanga.
• Unokudumba, ngakumbi kwimilenze esezantsi.
• Ulusu lwakho lubonisa ukwaluphala ngaphambi kwexesha.

Uvavanyo olunokwenziwa lunokubandakanya:

• Gcwalisa ubalo lwegazi
• Ukuxilongwa kwe-CT kwezintso
• Ipyramogram efakwa ngaphakathi (IVP)
• Isikrini seToxicology
• Uhlalutyo lomchamo
• Isifo sezintso

Iinjongo eziphambili zonyango kukuthintela ukonakala ngakumbi kwezintso kunye nokunyanga ukusilela kwezintso. Umboneleli wakho unokukuxelela ukuba uyeke ukuthatha zonke iipilisi zeentlungu, ngakumbi iziyobisi ze-OTC.

Ukunyanga ukungaphumeleli kwezintso, umboneleli wakho unokucebisa utshintsho lokutya kunye nokuthintelwa kolwelo. Ekugqibeleni, ukuhanjiswa kwedialysis okanye ukufakelwa kwezintso kunokufuneka.

Ukucebisa kunokukunceda uphuhlise ezinye iindlela zokulawula iintlungu ezingapheliyo.

Umonakalo kwizintso unokuba buhlungu kwaye ube wethutyana, okanye ixesha elingapheliyo nelide.

Iingxaki ezinokubangelwa yi-analgesic nephropathy zibandakanya:

• Ukungaphumeleli kwezintso
• Ukusilela kwezintso okungapheliyo
• Ingxaki yezintso apho izithuba phakathi kweetubules zezintso zivutha (i-nephritis yangaphakathi)
• Ukufa kweethishu kwiindawo apho ukuvuleka kwemibhobho yokuqokelela kungena kwizintso nalapho umchamo ungena kwii-ureters (i-renal papillary necrosis)
• Usulelo lomchamo oqhubekayo okanye oqhubeka ubuya
• Igazi elonyukayo
• Umhlaza kwizintso okanye ureter

Fowunela umnikezeli wakho ukuba unazo ezi zinto zilandelayo:

• Iimpawu ze-analgesic nephropathy, ngakumbi ukuba kudala usebenzisa iipilisi zentlungu
• Igazi okanye izinto eziqinileyo kumchamo wakho
• Inani lomchamo wakho lehlile

Landela imiyalelo yomboneleli wakho xa usebenzisa amayeza, kubandakanya iziyobisi ze-OTC. Musa ukuthatha ngaphezulu kwethamo elicetyiswayo ngaphandle kokucela umboneleli wakho.

Phenacetin nephritis; Nephropathy - iintlungu

• I-anatomy yezintso

UAronons JK. Paracetamol (acetaminophen) kunye nendibaniselwano. Ku: Aronson JK, ii-eds. Iziphumo ebezingalindelekanga zikaMeyler zeziyobisi. Ngomhla we-16. I-Waltham, MA: Elsevier; Ngo-2016: 474-493.

IParazella MA, iRosner MH. Izifo ze-tubulointerstitial. Ku: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, ii-eds. Brenner kunye noMphathi weZintso. Ngomhla we-11. IPhiladelphia, PA: Elsevier; 2020: isahluko 35.

I-Segal MS, i-Yu X. Amayeza e-Herbal kunye ne-over-counter kunye nezintso. Ku: Feehally J, Floege J, Tonelli M, Johnson RJ, ii-eds. I-Clinical Nephrology epheleleyo. Umhla wesi-6. IPhiladelphia, PA: Elsevier; I-2019: isahluko 76.