Isiphene somsebenzi weplatelet

Iziphene zomsebenzi weplatelet yokuzalwa yimeko ethintela ukujija kwezinto egazini, ezibizwa ngokuba ziiplatelets, ekubeni zisebenze ngendlela ebekufanele ukuba zisebenza ngayo. Iiplatelets zinceda i-clot yegazi. Ukuzalwa kuthetha ukuba khona kwasekuzalweni.

Iziphene zomsebenzi weplatelet wokuzalwa kukuphazamiseka kwegazi okubangela ukunciphisa ukusebenza kweplatelet.

Uninzi lwexesha, abantu abanezi ngxaki baneembali zosapho zokuphazamiseka kwegazi, ezinje:

• Isifo sikaBernard-Soulier senzeka xa iiplatelets zingenanto inamathela kwiindonga zemithambo yegazi. Iiplatelets zihlala zikhulu kwaye zincitshisiwe inani. Esi sifo sinokubangela ukopha kakhulu.
• IGlanzmann thrombasthenia yimeko ebangelwa kukungabikho kweprotein efunekayo ukuze iiplatelets zidibane. Iiplatelet ziqhelekileyo ngobukhulu obuqhelekileyo kunye nenombolo. Esi sifo sinokubangela nokopha kakhulu.
• Ukuphazamiseka kweplatelet pool pool (ekwabizwa ngokuba yiplatelet secretion disorder) kwenzeka xa izinto ezibizwa ngokuba ziigranu ngaphakathi kweeplatelets azigcinwanga okanye zikhutshwe ngokufanelekileyo. Iigranules zinceda ukuba iiplatelets zisebenze ngokufanelekileyo. Esi sifo sibangela ukutyumka okanye ukopha ngokulula.

Iimpawu zinokubandakanya nayiphi na kwezi zinto zilandelayo:

• Ukopha kakhulu ngexesha nasemva kotyando
• Iintsini zokopha
• Ukutyumza okulula
• Amaxesha anzima okuya exesheni
• Iimpumlo
• Ukopha ixesha elide ukonzakala okuncinci

Ezi mvavanyo zilandelayo zinokusetyenziselwa ukufumanisa le meko:

• Gcwalisa ubalo lwegazi (CBC)
• Ixesha lecandelo le-thromboplastin (PTT)
• Uvavanyo lokuhlanganiswa kweplatelet
• Ixesha leprothrombin (PT)
• Uhlalutyo lomsebenzi wePlatelet
• Ukuhamba kwecytometry

Unokufuna olunye uvavanyo. Izalamane zakho zisenokufuna ukuvavanywa.

Akukho lunyango oluthile kwezi ngxaki. Nangona kunjalo, umboneleli wakho wezempilo uya kujonga imeko yakho.

Unokufuna kwakhona:

• Ukuthintela ukuthatha i-aspirin kunye nezinye iziyobisi ezichasayo (i-NSAIDs), ezinje nge-ibuprofen kunye ne-naproxen, kuba zinokuzenza mandundu iimpawu zokopha.
• Utofelo-gazi, njengexesha lotyando okanye iinkqubo zamazinyo.

Akukho lunyango lokuphazamiseka kokuzalwa kweplatelet. Uninzi lwexesha, unyango lunokulawula ukopha.

Iingxaki zinokubandakanya:

• Ukopha kakhulu
• Ukunqongophala kwe-Iron anemia kubafazi abasexesheni

Fowunela umnikezeli wakho ukuba:

• Ukopha okanye utyumke kwaye awazi unobangela.
• Ukopha akuphenduli kwindlela eqhelekileyo yolawulo.

Uvavanyo lwegazi lunokufumanisa isini esinoxanduva lweplatelet defect. Unokuba unqwenela ukufumana ingcebiso ngemfuzo ukuba unembali yosapho yale ngxaki kwaye ucinga ukuba nabantwana.

Ingxaki yokugcina iplatelet yokugcina; Thrombasthenia kaGlanzmann; Isifo sikaBernard-Soulier; Iziphene zomsebenzi wePlatelet - ukuzalwa

• Ukubumba kwegazi
• Amahlwili egazi

UArnold DM, uMphathiswa weZeller, uSmith JW, uNazy I. Izifo zenombolo yeplatelet: i-immune thrombocytopenia, neonatal alloimmune thrombocytopenia, kunye ne-posttransfusion purpura. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 131.

Iholo JE. I-Hemostasis kunye nokuqina kwegazi. Ku: Iholo JE, ed. Incwadi kaGuyton kunye neHolo yePhysical Physiology. Umhla we-13. IPhiladelphia, PA: Elsevier; 2016: isahluko 37.

I-Nichols WL. Isifo seVon Willebrand kunye nokungaqheleki kokopha kweplatelet kunye nokusebenza kweethambo. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Umhla wama-25. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 173.