Meningitis - cryptococcal

I-Cryptococcal meningitis sisifo sokungunda sezicubu ezigubungele ingqondo kunye nentambo yomqolo. Ezi zihlunu zibizwa ngokuba zii-meninges.

Kwiimeko ezininzi, i-cryptococcal meningitis ibangelwa ngundo I-Cryptococcus neoformans. Lo mngundo ufumaneka emhlabeni jikelele. I-Cryptococcus gattii inokubangela ne-meningitis, kodwa le fomu inokubangela isifo nakwizigulana ezinamajoni omzimba aqhelekileyo.

Olu hlobo lwe-meningitis alusasazeki kumntu kumntu. Ngokwesiqhelo, isasazeka ngokuhamba kwegazi liye kwingqondo lisuka kwenye indawo emzimbeni onosulelo.

I-Cryptococcus neoformans i-meningitis ihlala ichaphazela abantu abanamajoni omzimba abuthathaka, kubandakanya abantu abane:

• UGawulayo
• I-Cirrhosis (uhlobo lwesifo sesibindi)
• Seswekile
• Ileukemia
• KwiLymphoma
• I-Sarcoidosis
• Ukufakelwa komzimba

Esi sifo sinqabile kubantu abanamajoni omzimba aqhelekileyo kwaye abanangxaki zempilo zexesha elide.

Olu hlobo lwe-meningitis luqala kancinci, ngaphezulu kweentsuku ezimbalwa ukuya kwiiveki ezimbalwa. Iimpawu zingabandakanya:

• Ifiva
• Ukuba nemibono
• Intloko ebuhlungu
• Ukutshintsha kwemeko yengqondo (ukudideka)
• Isicaphucaphu nokugabha
• Ubuntununtunu ekukhanyeni
• Intamo elukhuni

Umboneleli wakho wezempilo uya kukuvavanya kwaye akubuze malunga neempawu zakho.

I-lumbar puncture (impompo yomqolo) isetyenziselwa ukufumanisa isifo se-meningitis. Kolu vavanyo, isampulu ye-cerebrospinal fluid (CSF) iyasuswa kumqolo wakho kwaye ivavanywe.

Olunye uvavanyo olunokwenziwa lunokubandakanya:

• Inkcubeko yegazi
• I-x-ray yesifuba
• I-antigen ye-Cryptococcal kwi-CSF okanye igazi, ukukhangela izilwa-buhlungu
• Uviwo lwe-CSF lokubala kweeseli, iswekile, kunye neeproteni
• Ukuvavanywa kwentloko kwe-CT
• Ibala legram, amanye amabala akhethekileyo kunye nenkcubeko ye-CSF

Amayeza okubola asetyenziswa ukunyanga olu hlobo lwe-meningitis. Unyango (IV, ngokusebenzisa umthambo) unyango olunonyango lwe-amphotericin B lolona luqhelekileyo unyango. Ihlala idityaniswa kunye neyeza lomlomo elibizwa ngokuba yi-5-flucytosine.

Elinye ichiza lomlomo, i-fluconazole, ngeedosi eziphezulu zinokusebenza. Ukuba iyafuneka, iya kumiselwa kamva kwisifundo sesifo.

Abantu abafumana i-cryptococcal meningitis badinga amayeza exesha elide ukuthintela usulelo ukuba lungabuyi. Abantu abanamajoni omzimba abuthathaka, anje ngala ane-HIV / AIDS, bayakufuna unyango lwexesha elide ukuphucula amajoni abo omzimba.

Ezi ngxaki zinokwenzeka kwesi sifo:

• Umonakalo wobuchopho
• Ukuva okanye ukulahleka kombono
• IHydrocephalus (i-CSF egqithileyo kwingqondo)
• Ukuxhuzula
• Ukufa

I-Amphotericin B inokuba neziphumo ebezingalindelekanga ezinje:

• Isicaphucaphu nokugabha
• Umkhuhlane kunye nokubanda
• Ukudibana kunye nezihlunu
• Umonakalo wezintso

Fowunela inombolo yongxamiseko yendawo yakho (enje nge-911) ukuba uvelisa naziphi na iimpawu ezinzulu ezibhalwe apha ngasentla. I-Meningitis inokuba sisifo esisongela ubomi ngokukhawuleza.

Tsalela umnxeba kwindawo yakho yongxamiseko okanye uye kwigumbi likaxakeka ukuba ukrokrela i-meningitis kumntwana omncinci onezi mpawu:

• Ubunzima bokutya
• Isikhalo esiphakamileyo
• Ukucaphuka
• Ukuqhubeka, umkhuhlane ongachazwanga

I-Cryptococcal meningitis

• Inkqubo ye-nervous central kunye ne-peripheral system

Amaziko oLawulo lweNtsholongwane kunye noThintelo lwewebhusayithi. I-meningitis yomngundo. www.cdc.gov/meningitis/fungal.html. Ukuhlaziywa kwe-Agasti 06, 2019. Ifikeleleke ngoFebruwari 18, 2021.

UKauffman CA, u-Chen S. Cryptococcosis. Ku: IGoldman L, iSchafer AI, ii-eds. Amayeza eGoldman-Cecil. Ngomhla wama-26. IPhiladelphia, PA: Elsevier; 2020: isahl 317.

I-JR egqibeleleyo. I-Cryptococcosis (I-Cryptococcus neoformans kwaye I-Cryptococcus gattii). Ku: Bennett JE, Dolin R, Blaser MJ, ii-eds. Mandell, Douglas, kunye neBennett's Principles and Practice of Infectious Diseases. Umhla we-9. IPhiladelphia, PA: Elsevier; 2020: isahluko 262.