Subacute ukonakala ngokudibeneyo

I-Subacute degeneration edibeneyo (i-SCD) kukuphazamiseka komqolo, ingqondo, kunye ne-nerves. Kubandakanya ubuthathaka, iimvakalelo ezingaqhelekanga, iingxaki zengqondo kunye nobunzima bokubona.

I-SCD ibangelwa kukusilela kwe-vitamin B12. Ichaphazela ikakhulu intambo yomqolo. Kodwa iimpembelelo zayo kwingqondo nakwipheripheral (yomzimba) kwimithambo-luvo sisizathu segama "elidibeneyo." Ekuqaleni, isigubungelo semithambo (i-myelin sheath) sonakele. Emva kwexesha, yonke intsholongwane iyachaphazeleka.

Oogqirha abazi ngqo ukuba ukungabikho kwe-vitamin B12 kuyonakalisa njani imithambo-luvo. Kuyenzeka ukuba ukunqongophala kwale vithamini kubangele ii-acid ezingaqhelekanga ukuba zibumbe zijikeleze iiseli kunye nemithambo-luvo.

Abantu basemngciphekweni omkhulu wale meko ukuba ivithamin B12 ayinakufakwa emathunjini abo okanye ukuba:

• I-anemia enobungozi, imeko apho umzimba ungenayo iiseli ezibomvu zegazi ezaneleyo
• Ukuphazamiseka kwamathumbu amancinci, kubandakanya isifo seCrohn
• Iingxaki zifunxa izondlo, ezinokubakho emva kotyando lwesisu

Iimpawu zibandakanya:

• Iimvakalelo ezingaqhelekanga (ukubetha kunye nokuqaqamba)
• Ubuthathaka bemilenze, iingalo, okanye ezinye iindawo

Ezi mpawu ziba kancinci kancinci kwaye zihlala zivakala kumacala omabini omzimba.

Njengoko esi sifo siya sisiba mandundu, iimpawu zinokubandakanya oku kulandelayo:

• Ukuqaqadeka, ukuqina okanye ukungahambi kakuhle
• Guqula kwimeko yengqondo, ezinje ngememori, ukungakhathali, ukungakhathali, ukudideka, okanye isifo sengqondo esixhalabisayo
• Ukwehla kombono
• Uxinzelelo
• Ukulala
• Ukuhamba okungazinzanga kunye nelahleko eseleyo
• Ukuwa ngenxa yokungalingani

Umboneleli wezempilo uya kwenza uvavanyo lomzimba. Uvavanyo luhlala lubonisa ubuthathaka bemisipha kunye neengxaki zovakalelo kumacala omabini omzimba, ngakumbi emilenzeni. I-Knee jerk reflexes zihlala zincipha okanye zilahlekile. Imisipha inokuba ne-spasticity. Kunokuncitshiswa izivamvo zokuchukumisa, iintlungu kunye nobushushu.

Utshintsho lwengqondo luqala ngokulibala kancinci ukuya kwisifo sengqondo esixhalabisayo okanye isifo sengqondo. Isifo sengqondo esixhalabisayo asiqhelekanga, kodwa kwezinye iimeko, luphawu lokuqala lwesifo.

Uvavanyo lwamehlo lunokubonisa ukonakala kwithambo le-optic, imeko ebizwa ngokuba yi-optic neuritis. Iimpawu zokuvuvukala kwemithambo-luvo zinokubonwa ngexesha lovavanyo lwe-retina. Kukho ukubakho kweempendulo zomfundi ezingaqhelekanga, ukulahleka kombono obukhali, kunye nolunye utshintsho.

Uvavanyo lwegazi olunoku-odolwa lubandakanya:

• Gcwalisa ubalo lwegazi (CBC)
• Inqanaba legazi leVitamin B12
• Inqanaba legazi leMethylmalonic acid

I-Vitamin B12 inikwa, ihlala itofwa kwimisipha. Inaliti zihlala zinikwa kanye ngemini kangangeveki, emva koko ngeveki malunga nenyanga enye, emva koko ngenyanga. Izongezo zeVitamin B12, nokuba ngenaliti okanye iipilisi zedosi ephezulu, kufuneka ziqhubeke ubomi bakho bonke ukuthintela ukubuya kweempawu.

Unyango lwakwangoko luphucula ithuba lesiphumo esihle.

Ukusebenza kakuhle komntu kuxhomekeke ekubeni wayeneempawu ezingakanani ngaphambi kokuba afumane unyango. Ukuba unyango lufunyenwe kwiiveki nje ezimbalwa, kunokulindelwa ukuchacha okupheleleyo. Ukuba unyango lulibazisekile ixesha elingaphezulu kweenyanga ezi-1 okanye ezi-2, ukubuyela ngokupheleleyo akunakwenzeka.

Ukunganyangwa, iziphumo ze-SCD kukuqhubeka kunye nomonakalo osisigxina kwinkqubo yeemvakalelo.

Fowunela umboneleli wakho ukuba iimvakalelo ezingaqhelekanga, ubuthathaka bemisipha, okanye ezinye iimpawu ze-SCD zikhula. Oku kubaluleke ngakumbi ukuba wena okanye ilungu losapho une-anemia eyingozi okanye ezinye izinto ezinobungozi.

Ezinye izidlo zemifuno, ngakumbi i-vegan, inokuba sezantsi kwi-vitamin B12. Ukuthatha isongezelelo kunokunceda ukukhusela i-SCD.

Subacute ukonakala ngokudibeneyo kwethambo lomqolo; I-SCD

• Inkqubo ye-nervous central kunye ne-peripheral system
• Inkqubo ye-nervous central

IPytel P, u-Anthony DC. Imithambo yoluvo kunye nezihlunu zamathambo. Ku: Kumar V, Abbas AK, Aster JC, ii-eds. Robbins kunye neCotran Pathologic Isiseko seZifo. Umhla we-9. IPhiladelphia, PA: Elsevier Saunders; 2015: isahluko 27.

Ke YT. Ukusilela kwezifo kwinkqubo yemithambo-luvo. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ii-eds. I-Neurology kaBradley kwiKlinikhi yokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 85.