Unyango lwe-Photodynamic kumhlaza

Unyango lwe-Photodynamic (PDT) lisebenzisa iyeza kunye nohlobo oluthile lokukhanya ukubulala iiseli zomhlaza.

Okokuqala, ugqirha utofa iyeza elifunxwa ziiseli kuwo wonke umzimba. Iyeza lihlala kwiiseli zomhlaza ixesha elide kunokuba lihlale kwiseli eqhelekileyo, esempilweni.

Emva kweentsuku ezi-1 ukuya kwezi-3, iyeza limkile kwiiseli ezinempilo, kodwa lihlala kwiiseli zomhlaza. Emva koko, ugqirha uyalela ukukhanya kwiiseli zomhlaza usebenzisa i-laser okanye omnye umthombo wokukhanya. Ukukhanya kudala amayeza ukuba avelise uhlobo lweoksijini ephatha umhlaza ngoku:

• Ukubulala iiseli zomhlaza
• Ukonakalisa iiseli zegazi kwi-tumor
• Ukunceda inkqubo yosulelo-yokulwa komzimba ukuba ihlasele ithumba

Ukukhanya kunokuvela kwilaser okanye komnye umthombo. Ukukhanya kuhlala kufakwa ngombhobho omncinci, okhanyisiweyo obekwa ngaphakathi emzimbeni. Iintsinga ezincinci ekupheleni kwetyhubhu ziqondisa ukukhanya kwiiseli zomhlaza. I-PDT inyanga umhlaza kwi:

• Amaphaphu, esebenzisa i-bronchoscope
• I-Esophagus, isebenzisa i-endoscopy ephezulu

Oogqirha basebenzisa ii-diode ezikhanyisa ukukhanya (ii-LED) ukunyanga umhlaza wolusu. Iyeza lifakwa kulusu, kwaye ukukhanya kuyakhanya kulusu.

Olunye uhlobo lwe-PDT lusebenzisa umatshini ukuqokelela igazi lomntu, elinyangwa ngeyeza lize libonakaliswe kukukhanya. Emva koko, igazi libuyiselwa emntwini. Oku kusetyenziselwa ukunyanga iimpawu zohlobo oluthile lwe-lymphoma.

I-PDT inezibonelelo ezininzi. Umzekelo,

• Iithagethi ziiseli zomhlaza kuphela, hayi iiseli eziqhelekileyo
• Unokuphindwaphindwa amaxesha amaninzi kwindawo enye, ngokungafaniyo nonyango lwemitha
• Ingaphantsi komngcipheko kunokuhlinzwa
• Kuthatha ixesha elincinci kunye neendleko ezingaphantsi kolunye unyango lomhlaza

Kodwa i-PDT ikwanazo neengxaki. Inokuphatha kuphela indawo apho ukukhanya kunokufikelela khona. Oko kuthetha ukuba inokusetyenziselwa kuphela ukunyanga umhlaza ngaphakathi okanye phantsi nje kolusu, okanye kwilayini yamanye amalungu. Kananjalo, ayinakusetyenziswa kubantu abanezifo ezithile zegazi.

Zimbini iziphumo ebezingalindelekanga eziphambili ze-PDT. Enye yempendulo ebangelwa kukukhanya okwenza ulusu ludumbe, lutshiswe lilanga, okanye luqatywe ngumhlana emva nje kwemizuzu embalwa elangeni okanye kufutshane nezibane eziqaqambileyo. Le mpendulo inokuhlala ixesha elide kwiinyanga ezi-3 emva konyango. Ukuyiphepha:

• Vala iisheyinti namakhethini kwiifestile nakwizibane esibhakabhakeni ekhayeni lakho ngaphambi kokuba ufumane unyango.
• Yiza nezibuko zelanga ezimnyama, iiglavu, umnqwazi obanzi, kwaye unxibe iimpahla ezigubungela isikhumba sakho kangangoko kunyango lwakho.
• Ubuncinci inyanga emva konyango, hlala ngaphakathi kangangoko, ngakumbi phakathi kwe-10 kusasa kunye ne-4 pm.
• Gubungela ulusu lwakho nanini na uphuma ngaphandle, nokuba kungamafu ashushu kwaye usemotweni. MUSA ukubala kwi-sunscreen, ayizukuthintela impendulo.
• MUSA ukusebenzisa izibane zokufunda kwaye uphephe izibane zoviwo, ezinje ngohlobo olusetyenziswa ngugqirha wamazinyo.
• MUSA ukusebenzisa izixhobo zokumisa iinwele ezinje ngezi zikwizaluni zeenwele. Sebenzisa kuphela ubushushu obuphantsi xa usomisa iinwele ngesandla.

Esinye isiphumo esiphambili kukudumba, okunokubangela iintlungu okanye ingxaki yokuphefumla okanye ukugwinya. Oku kuxhomekeke kummandla onyangiweyo. Iziphumo ebezingalindelekanga zezexeshana.

Unyango ngemifanekiso; Unyango ngemichiza; Unyango lwefotoradiation; Umhlaza womqala - iphotoodynamic; Umhlaza wokudumba - photodynamic; Umhlaza wemiphunga - photodynamic

Umbutho waseMelika woMhlaza. Ukufumana unyango lwe-photodynamic. www.cancer.org/treatment/treatment-and-side-effects/treatment-types/radiation/photodynamic-therapy.html. Ukuhlaziywa ngoDisemba 27, 2019. Ifikeleleke ngo-Matshi 20, 2020.

U-Lui H, u-Richer V. Unyango lwe-Photodynamic. Ku: I-Bolognia JL, uSchaffer JV, uCerroni L, ii-eds. Dermatology. Ngomhla we-4. IPhiladelphia, PA: Elsevier; I-2018: isahluko 135.

Kwiwebhusayithi yeZiko loMhlaza weSizwe. Unyango lwe-Photodynamic kumhlaza. www.cancer.gov/about-cancer/treatment/types/surgery/photodynamic-fact-sheet. Ukuhlaziywa kweSeptemba 6, 2011. Ifikeleleke ngoNovemba 11, 2019.

• Umhlaza