Uvavanyo lwegazi lwe-Alanine transaminase (ALT)

Uvavanyo lwegazi lwe-alanine transaminase (ALT) lulinganisa inqanaba le-enzyme ALT egazini.

Isampulu yegazi iyafuneka.

Akukho lungiselelo lukhethekileyo luyafuneka.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubetha okanye ukukrala kancinci. Oku kuya kuhamba kungekudala.

I-ALT yi-enzyme efumaneka kwinqanaba eliphezulu esibindini. I-enzyme yiprotein ebangela utshintsho oluthile lweekhemikhali emzimbeni.

Ukwenzakala kwisibindi kuphumela ekukhululweni kwe-ALT egazini.

Olu vavanyo lwenziwa ikakhulu kunye nolunye uvavanyo (njenge-AST, ALP, kunye ne-bilirubin) ukufumanisa nokujonga isifo sesibindi.

Uluhlu oluqhelekileyo ngu-4 ukuya ku-36 U / L.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye zinokuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Ukunyuka kwenqanaba le-ALT kuhlala kungumqondiso wesifo sesibindi. Isifo sesibindi sinokwenzeka ngakumbi xa amanqanaba ezinto ahlolwe lolunye uvavanyo lwegazi lesibindi nawo enyukile.

Inqanaba le-ALT elonyukayo linokubangelwa yiyo nayiphi na kwezi zinto zilandelayo:

• Ukuqhekeka kwesibindi (i-cirrhosis)
• Ukufa kwezihlunu zesibindi
• Ukudumba kunye nokutsha kwesibindi (hepatitis)
• Intsimbi eninzi emzimbeni (hemochromatosis)
• Amanqatha amaninzi esibindi (isibindi esinamafutha)
• Ukungabikho kokuhamba kwegazi kwisibindi (isibindi ischemia)
• Ithumba lesibindi okanye umhlaza
• Ukusetyenziswa kweziyobisi eziyityhefu kwisibindi
• Mononucleosis ("mono")
• I-pancreas edumbileyo kunye ne-inflamed (pancreatitis)

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye nakwelinye icala lomzimba liye kwelinye. Ukuthatha igazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (ukuqokelela kwegazi phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

I-SGPT; I-Serum glutamate pyruvate transaminase; UAlanine transaminase; UAlanine aminotransferase

IChernecky CC, iBerger BJ. UAlanine aminotransferase (ALT, alanine transaminase, SGPT) -iserum. Ku: IChernecky CC, iBerger BJ, ii-eds. Iimvavanyo zaselebhu kunye neenkqubo zokuqonda isifo. Umhla wesi-6. ISt Louis, MO: Elsevier Saunders; Ngo-2013: 109-110.

UPincus MR, u-Tierno PM, uGleeson E, uBowne WB, uBluth MH. Ukuvavanywa kokusebenza kwesibindi. Ku: McPherson RA, Pincus MR, ii-eds. Ukuchongwa kweKlinikhi kaHenry kunye noLawulo ngeendlela zeLebhu. Umhla we-23. ISt Louis, MO: Elsevier; I-2017: isahluko 21.

IPratt DS. I-chemistry yesibindi kunye novavanyo lomsebenzi. Ku: UFeldman M, uFriedman LS, uBrandt LJ, ii-eds. Sleisenger kunye neFordtran's Gastrointestinal and Liver Disease. Ngomhla we-10. IPhiladelphia, PA: Elsevier Saunders; Ngo-2016: isahluko 73.