Uvavanyo lweseli yokugula

Uvavanyo lweseli yesigulana lukhangela i-hemoglobin engaqhelekanga egazini ebangela isifo sesigulo sesigulo.

Isampulu yegazi iyafuneka.

Xa kufakwa inaliti ukutsala igazi, abanye abantu baziva iintlungu eziphakathi. Abanye baziva behlaba okanye behlaba kuphela. Emva koko, kunokubakho ukubethabethana okanye ukugruzuka. Oku kuya kuhamba kungekudala.

Olu vavanyo lwenziwa ukuxelela ukuba umntu une-hemoglobin engaqhelekanga ebangela isifo se-sickle cell kunye ne-sickle cell trait. IHemoglobin yiprotein ekwiiseli ezibomvu zegazi ezithwala ioksijini.

Kwisifo se-sickle cell, umntu uneempawu ezimbini ezingaqhelekanga ze-hemoglobin S. Umntu onesimilo seseli enerhengqa unenye kuphela yezi ntlobo zofuzo zingaqhelekanga kwaye akanazo iimpawu, okanye zincinci kuphela.

Olu vavanyo aluxeleli umahluko phakathi kwezi meko zimbini. Olunye uvavanyo, olubizwa ngokuba yihemoglobin electrophoresis, luyakwenziwa ukuxelela ukuba yeyiphi imeko umntu anayo.

Iziphumo zovavanyo eziqhelekileyo zibizwa ngokuba ziziphumo ezibi.

Amaxabiso esiqhelo ahluka kancinci phakathi kweelebhu ezahlukeneyo. Ezinye iilebhu zisebenzisa imilinganiselo eyahlukeneyo okanye ukuvavanya iisampulu ezahlukeneyo. Thetha nomboneleli wakho wezempilo malunga nentsingiselo yeziphumo zakho zovavanyo.

Iziphumo zovavanyo ezingaqhelekanga zibonisa ukuba umntu unokuba nenye yezi:

• Isifo seSickle cell
• Uphawu lweseli lokugula

Ukusilela kwentsimbi okanye utofelo-gazi kwiinyanga ezi-3 ezidlulileyo kunokubangela iziphumo ezibi ezingezizo. Oku kuthetha ukuba umntu unokuba ne-hemoglobin engaqhelekanga yeseli yesikela, kodwa ezinye izinto zenza ukuba iziphumo zabo zovavanyo zibonakale zibi (ziqhelekileyo).

Akukho mngcipheko ubandakanyekileyo ekuthatheni igazi lakho. Imithambo kunye nemithambo iyahluka ngobukhulu ukusuka komnye umntu ukuya komnye, kwaye ukusuka kwelinye icala lomzimba ukuya kwelinye. Ukufumana isampulu yegazi kwabanye abantu kunokuba nzima ngakumbi kunabanye.

Eminye imingcipheko enxulumene nokutsalwa kwegazi incinci, kodwa inokubandakanya:

• Ukopha kakhulu
• Ukufa isiqaqa okanye ukuziva ungenantloko
• Ukugqobhoza okuninzi ukufumana imithambo
• I-Hematoma (igazi elakhiweyo phantsi kolusu)
• Usulelo (umngcipheko omncinci nangaliphi na ixesha ulusu lwaphukile)

Sickledex; Uvavanyo lwe-Hgb S

• Iiseli ezibomvu zegazi, iiseli zerhengqa
• Iiseli ezibomvu zegazi-iiseli ezininzi zeerheng
• Iiseli ezibomvu zegazi - iiseli zerhengqa
• Iiseli ezibomvu zegazi - irhengqa kunye nePappenheimer

USaunthararajah Y, Vichinsky EP. Isifo seSickle cell: Iimpawu zeklinikhi kunye nolawulo. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ii-eds. I-Hematology: Imigaqo esisiseko kunye nokuziqhelanisa. Umhla wesi-7. IPhiladelphia, PA: Elsevier; I-2018: isahluko 42.